Limbal Stem Cell Deficiency: Current Treatment Options and Emerging Therapies
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Title
Limbal Stem Cell Deficiency: Current Treatment Options and Emerging Therapies
Authors
Keywords
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Journal
Stem Cells International
Volume 2016, Issue -, Pages 1-22
Publisher
Hindawi Limited
Online
2015-12-15
DOI
10.1155/2016/9798374
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- (2014) Thomas A Hogerheyde et al. Biomedical Materials
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- (2014) GeetaK Vemuganti et al. INDIAN JOURNAL OF OPHTHALMOLOGY
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- (2014) Jui-Yang Lai et al. International Journal of Nanomedicine
- Human Limbal Mesenchymal Cells Support the Growth of Human Corneal Epithelial Stem/Progenitor Cells
- (2014) M. N. Nakatsu et al. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
- Results of a phase I/II clinical trial: standardized, non-xenogenic, cultivated limbal stem cell transplantation
- (2014) Nadia Zakaria et al. Journal of Translational Medicine
- ABCB5 is a limbal stem cell gene required for corneal development and repair
- (2014) Bruce R. Ksander et al. NATURE
- Reconstruction of Auto-Tissue-Engineered Lamellar Cornea by Dynamic Culture for Transplantation: A Rabbit Model
- (2014) Zheng Wu et al. PLoS One
- Localisation of Epithelial Cells Capable of Holoclone Formation In Vitro and Direct Interaction with Stromal Cells in the Native Human Limbal Crypt
- (2014) Marc A. Dziasko et al. PLoS One
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- (2014) Sai Kolli et al. STEM CELLS
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- (2014) Qing Zhou et al. Human Cell
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- Small-Molecule Induction Promotes Corneal Epithelial Cell Differentiation from Human Induced Pluripotent Stem Cells
- (2014) Alexandra Mikhailova et al. Stem Cell Reports
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- (2013) Berkay Ozcelik et al. Acta Biomaterialia
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- Use of a Silk Fibroin-Chitosan Scaffold to Construct a Tissue-Engineered Corneal Stroma
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- (2013) Jui-Yang Lai et al. Journal of Biomedical Nanotechnology
- In vivo biocompatibility of two PEG/PAA interpenetrating polymer networks as corneal inlays following deep stromal pocket implantation
- (2013) Xiao Wei Tan et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- Chitosan–gelatin biopolymers as carrier substrata for limbal epithelial stem cells
- (2013) Ana de la Mata et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
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- (2013) Linan Guan et al. JOURNAL OF MOLECULAR HISTOLOGY
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- (2013) Chris Bath et al. PLoS One
- A novel cross-linked human amniotic membrane for corneal implantations
- (2013) S Sekar et al. PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE
- Rapidly constructed scaffold-free embryonic stem cell sheets for ocular surface reconstruction
- (2013) Wei Zhang et al. SCANNING
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- (2013) P. Ordonez et al. Stem Cell Research
- Mesenchymal Stem Cells, Nanofiber Scaffolds and Ocular Surface Reconstruction
- (2013) Vladimir Holan et al. Stem Cell Reviews and Reports
- Reconstruction of Functional Ocular Surface by Acellular Porcine Cornea Matrix Scaffold and Limbal Stem Cells Derived from Human Embryonic Stem Cells
- (2013) Jing Zhu et al. TISSUE ENGINEERING PART A
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- Fish Scale Collagen-A Novel Material for Corneal Tissue Engineering
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- (2012) Iker Garcia et al. OPHTHALMOLOGY
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- Cultivation and Characterization of Cornea Limbal Epithelial Stem Cells on Lens Capsule in Animal Material-Free Medium
- (2012) Réka Albert et al. PLoS One
- Plastic Compressed Collagen as a Novel Carrier for Expanded Human Corneal Endothelial Cells for Transplantation
- (2012) Hannah J. Levis et al. PLoS One
- Concise Review: Limbal Stem Cell Deficiency, Dysfunction, and Distress
- (2012) Sajjad Ahmad Stem Cells Translational Medicine
- Corneal changes in ectrodactyly–ectodermal dysplasia–cleft lip and palate syndrome: case series and literature review
- (2012) Anthony F. Felipe et al. INTERNATIONAL OPHTHALMOLOGY
- Limbal stem cell deficiency in patients with inherited stem cell disorder of dyskeratosis congenita
- (2012) Deniz Aslan et al. INTERNATIONAL OPHTHALMOLOGY
- Human corneal epithelial equivalents constructed on Bombyx mori silk fibroin membranes
- (2011) Laura J. Bray et al. BIOMATERIALS
- Keratin films for ocular surface reconstruction
- (2011) Stephan Reichl et al. BIOMATERIALS
- Clinical outcomes of xeno-free autologous cultivated limbal epithelial transplantation: a 10-year study
- (2011) V. S. Sangwan et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Limbal stem cell disease: management with scleral lenses
- (2011) Muriel M Schornack Clinical and Experimental Optometry
- Culture of Corneal Limbal Epithelial Stem Cells: Experience From Benchtop to Bedside in a Tertiary Care Hospital in India
- (2011) Shweta Sharma et al. CORNEA
- Synthesis, Characterization, and In Vitro Evaluation of a Hydrogel-Based Corneal Onlay
- (2011) Abigail M. Oelker et al. IEEE TRANSACTIONS ON NANOBIOSCIENCE
- Porous Silk Fibroin Film as a Transparent Carrier for Cultivated Corneal Epithelial Sheets
- (2011) Kazunari Higa et al. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
- Photochemical cross-linking of plastically compressed collagen gel produces an optimal scaffold for corneal tissue engineering
- (2011) Shengli Mi et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Toward the development of an artificial cornea: Improved stability of interpenetrating polymer networks
- (2011) Laura Hartmann et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
- 13 years of cultured limbal epithelial cell therapy: A review of the outcomes
- (2011) Oliver Baylis et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Corneal epithelialisation on surface-modified hydrogel implants
- (2011) Aihua Ma et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- Long-term Outcome of Cultivated Oral Mucosal Epithelial Sheet Transplantation in Treatment of Total Limbal Stem Cell Deficiency
- (2011) Yoshiyuki Satake et al. OPHTHALMOLOGY
- Changes in Culture Expanded Human Amniotic Epithelial Cells: Implications for Potential Therapeutic Applications
- (2011) Gita Pratama et al. PLoS One
- Umbilical Cord Lining Stem Cells as a Novel and Promising Source for Ocular Surface Regeneration
- (2011) Hasan Mahmud Reza et al. Stem Cell Reviews and Reports
- Comparative Analysis of Human-Derived Feeder Layers with 3T3 Fibroblasts for the Ex Vivo Expansion of Human Limbal and Oral Epithelium
- (2011) Sandhya M. Sharma et al. Stem Cell Reviews and Reports
- Rapidly Constructed Scaffold-Free Cornea Epithelial Sheets for Ocular Surface Reconstruction
- (2011) Wei Zhang et al. TISSUE ENGINEERING PART C-METHODS
- Carbodiimide cross-linked amniotic membranes for cultivation of limbal epithelial cells
- (2010) David Hui-Kang Ma et al. BIOMATERIALS
- Plastic compressed collagen as a biomimetic substrate for human limbal epithelial cell culture
- (2010) Hannah J. Levis et al. BIOMATERIALS
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- (2010) T. Nakamura et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- A novel method of culturing human oral mucosal epithelial cell sheet using post-mitotic human dermal fibroblast feeder cells and modified keratinocyte culture medium for ocular surface reconstruction
- (2010) Y. Oie et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Midterm Outcomes of Autologous Cultivated Limbal Stem Cell Transplantation With or Without Penetrating Keratoplasty
- (2010) Alireza Baradaran-Rafii et al. CORNEA
- Ocular Surface Reconstruction With Cultivated Limbal Epithelium in a Patient With Unilateral Stem Cell Deficiency Caused by Epidermolysis Bullosa Dystrophica Hallopeau-Siemens
- (2010) Melissa Thanos et al. CORNEA
- Evaluation of Molecular Markers in Corneal Regeneration by Means of Autologous Cultures of Limbal Cells and Keratoplasty
- (2010) Rossella Anna Maria Colabelli Gisoldi et al. CORNEA
- Value of human amniotic epithelial cells in tissue engineering for cornea
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- Plastic compression of a collagen gel forms a much improved scaffold for ocular surface tissue engineering over conventional collagen gels
- (2010) Shengli Mi et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
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- Supermacroprous chitosan-agarose-gelatin cryogels: in vitro characterization and in vivo assessment for cartilage tissue engineering
- (2010) S. Bhat et al. Journal of the Royal Society Interface
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- (2010) Qicheng Ke et al. Journal of Tissue Engineering and Regenerative Medicine
- Optimization of culture conditions for an efficient xeno-feeder free limbal cell culture system towards ocular surface regeneration
- (2010) Viji Mary Varghese et al. MICROSCOPY RESEARCH AND TECHNIQUE
- Epigenetic memory in induced pluripotent stem cells
- (2010) K. Kim et al. NATURE
- Limbal Stem-Cell Therapy and Long-Term Corneal Regeneration
- (2010) Paolo Rama et al. NEW ENGLAND JOURNAL OF MEDICINE
- Using poly(lactide-co-glycolide) electrospun scaffolds to deliver cultured epithelial cells to the cornea
- (2010) Pallavi Deshpande et al. Regenerative Medicine
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- (2009) Hanan Stein et al. BIOMACROMOLECULES
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- (2009) Christopher R. McLaughlin et al. BIOMATERIALS
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- (2009) V. Barbaro et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Impression cytology findings in bullous keratopathy
- (2009) F. d. S. Paris et al. BRITISH JOURNAL OF OPHTHALMOLOGY
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- (2009) J. Hong et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Serum eye drops, amniotic membrane and limbal epithelial stem cells—tools in the treatment of ocular surface disease
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- (2009) B. G. Monteiro et al. CELL PROLIFERATION
- In vivoconfocal microscopy of the bulbar conjunctiva
- (2009) Nathan Efron et al. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Ocular Surface Reconstruction in Graft-Versus-Host Disease With HLA-Identical Living-Related Allogeneic Cultivated Limbal Epithelium After Hematopoietic Stem Cell Transplantation From the Same Donor
- (2009) Daniel Meller et al. CORNEA
- Dyskeratosis congenita and limbal stem cell deficiency
- (2009) Deniz Aslan et al. EXPERIMENTAL EYE RESEARCH
- Artificial corneas: a regenerative medicine approach
- (2009) M Griffith et al. EYE
- Collagen vitrigel membranes for thein vitroreconstruction of separate corneal epithelial, stromal, and endothelial cell layers
- (2009) Winnette McIntosh Ambrose et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
- Successful Clinical Implementation of Corneal Epithelial Stem Cell Therapy for Treatment of Unilateral Limbal Stem Cell Deficiency
- (2009) Sai Kolli et al. STEM CELLS
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- (2009) Nick Di Girolamo et al. TRANSPLANTATION
- Contributions of Mouse Genetic Background and Age on Anterior Lens Capsule Thickness
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