Slowly Delivered Icariin/Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells to Promote the Healing of Calvarial Critical-Size Bone Defects

Icariin induces osteogenic differentiation of bone mesenchymal stem cells in a MAPK-dependent manner

(2015) Yuqiong Wu et al.   CELL PROLIFERATION

Systemic and Local Administration of Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells Promotes Fracture Healing in Rats

(2015) Shuo Huang et al.   CELL TRANSPLANTATION

Icariin recovers the osteogenic differentiation and bone formation of bone marrow stromal cells from a rat model of estrogen deficiency-induced osteoporosis

(2015) ZHIQIANG LUO et al.   Molecular Medicine Reports

Icariin stimulates the osteogenic differentiation of rat bone marrow stromal cells via activating the PI3K–AKT–eNOS–NO–cGMP–PKG

(2014) Yuan-Kun Zhai et al.   BONE

BMP-Functionalised Coatings to Promote Osteogenesis for Orthopaedic Implants

(2014) Jianfeng Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Siliceous mesostructured cellular foams/ poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) composite biomaterials for bone regeneration

(2014) Shengbing Yang et al.   International Journal of Nanomedicine

Icariin may benefit the mesenchymal stem cells of patients with steroid-associated osteonecrosis by ABCB1-promoter demethylation: a preliminary study

(2014) Z.-B. Sun et al.   OSTEOPOROSIS INTERNATIONAL

From isolation to implantation: a concise review of mesenchymal stem cell therapy in bone fracture repair

(2014) Luke Watson et al.   Stem Cell Research & Therapy

Autologous vs. allogenic mesenchymal progenitor cells for the reconstruction of critical sized segmental tibial bone defects in aged sheep

(2013) A. Berner et al.   Acta Biomaterialia

Icariin Augments Bone Formation and Reverses the Phenotypes of Osteoprotegerin-Deficient Mice through the Activation of Wnt/β-Catenin-BMP Signaling

(2013) Xiao-Feng Li et al.   Evidence-based Complementary and Alternative Medicine

Icariin: Does It Have An Osteoinductive Potential for Bone Tissue Engineering?

(2013) Xin Zhang et al.   PHYTOTHERAPY RESEARCH

The signaling and functions of heterodimeric bone morphogenetic proteins

(2012) Jing Guo et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Icariin promotes bone formation via the BMP-2/Smad4 signal transduction pathway in the hFOB 1.19 human osteoblastic cell line

(2012) WENNA LIANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Icariin enhances the healing of rapid palatal expansion induced root resorption in rats

(2012) Feng Wang et al.   PHYTOMEDICINE

Icariin stimulates MC3T3-E1 cell proliferation and differentiation through up-regulation of bone morphogenetic protein-2

(2011) Ying Zhang   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Sol–gel silica-based biomaterials and bone tissue regeneration

(2010) Daniel Arcos et al.   Acta Biomaterialia

Icariin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro

(2010) Hui-Ping Ma et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Icariin inhibits osteoclast differentiation and bone resorption by suppression of MAPKs/NF-κB regulated HIF-1α and PGE2 synthesis

(2010) Tsai-Pei Hsieh et al.   PHYTOMEDICINE

Mesenchymal Stem Cells for Bone Repair and Metabolic Bone Diseases

(2009) Anita H. Undale et al.   MAYO CLINIC PROCEEDINGS

Icariin isolated from Epimedium pubescens regulates osteoblasts anabolism through BMP-2, SMAD4, and Cbfa1 expression

(2009) Tsai-Pei Hsieh et al.   PHYTOMEDICINE

Short-term Osteoclastic Activity Induced by Locally High Concentrations of Recombinant Human Bone Morphogenetic Protein–2 in a Cancellous Bone Environment

(2009) Jeffrey M. Toth et al.   SPINE

Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells

(2008) Byung-Hee Chung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Calvarial bone regeneration by a combination of natural anorganic bovine-derived hydroxyapatite matrix coupled with a synthetic cell-binding peptide (PepGen™): an experimental study in rats

(2008) Nikos Mardas et al.   CLINICAL ORAL IMPLANTS RESEARCH

Nonunions and the Potential of Stem Cells in Fracture-Healing

(2008) Susan S. Tseng et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME