The Application of Human iPSCs in Neurological Diseases: From Bench to Bedside
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Title
The Application of Human iPSCs in Neurological Diseases: From Bench to Bedside
Authors
Keywords
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Journal
Stem Cells International
Volume 2016, Issue -, Pages 1-10
Publisher
Hindawi Limited
Online
2016-01-07
DOI
10.1155/2016/6484713
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Note: Only part of the references are listed.- Generating iPSCs: Translating Cell Reprogramming Science into Scalable and Robust Biomanufacturing Strategies
- (2015) Marli Silva et al. Cell Stem Cell
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- (2015) Penelope J. Hallett et al. Cell Stem Cell
- Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells
- (2015) Tongbiao Zhao et al. Cell Stem Cell
- How to make a midbrain dopaminergic neuron
- (2015) E. Arenas et al. DEVELOPMENT
- Cell-based therapies for Parkinson disease—past insights and future potential
- (2015) Roger A. Barker et al. Nature Reviews Neurology
- Induced pluripotent stem cells as a model for diabetes investigation
- (2015) J. Stepniewski et al. Scientific Reports
- Human-induced pluripotent stem cells generated from intervertebral disc cells improve neurologic functions in spinal cord injury
- (2015) Jinsoo Oh et al. Stem Cell Research & Therapy
- Autologous Hematopoietic Stem Cell Transplantation-10 Years of Data From a Developing Country
- (2015) Natasha Ali et al. Stem Cells Translational Medicine
- High-Throughput Screening to Identify Compounds That Increase Fragile X Mental Retardation Protein Expression in Neural Stem Cells Differentiated From Fragile X Syndrome Patient-Derived Induced Pluripotent Stem Cells
- (2015) Daman Kumari et al. Stem Cells Translational Medicine
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons
- (2014) Christina R. Muratore et al. HUMAN MOLECULAR GENETICS
- Fetal-cell revival for Parkinson’s
- (2014) Alison Abbott NATURE
- Pluripotent stem cells in regenerative medicine: challenges and recent progress
- (2014) Viviane Tabar et al. NATURE REVIEWS GENETICS
- Tumorigenicity Studies of Induced Pluripotent Stem Cell (iPSC)-Derived Retinal Pigment Epithelium (RPE) for the Treatment of Age-Related Macular Degeneration
- (2014) Hoshimi Kanemura et al. PLoS One
- Characterization and Molecular Profiling of PSEN1 Familial Alzheimer's Disease iPSC-Derived Neural Progenitors
- (2014) Andrew A. Sproul et al. PLoS One
- Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance
- (2014) Patricia .E de Almeida et al. Nature Communications
- iPSC-Derived Neural Stem Cells Act via Kinase Inhibition to Exert Neuroprotective Effects in Spinal Muscular Atrophy with Respiratory Distress Type 1
- (2014) Chiara Simone et al. Stem Cell Reports
- Coordination of Engineered Factors with TET1/2 Promotes Early-Stage Epigenetic Modification during Somatic Cell Reprogramming
- (2014) Gengzhen Zhu et al. Stem Cell Reports
- Cerebral Organoids in a Dish: Progress and Prospects
- (2013) Marina Bershteyn et al. CELL
- Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging
- (2013) Justine D. Miller et al. Cell Stem Cell
- Therapeutic Translation of iPSCs for Treating Neurological Disease
- (2013) Diana X. Yu et al. Cell Stem Cell
- Lack of Immune Response to Differentiated Cells Derived from Syngeneic Induced Pluripotent Stem Cells
- (2013) Prajna Guha et al. Cell Stem Cell
- Next-Generation Regenerative Medicine: Organogenesis from Stem Cells in 3D Culture
- (2013) Yoshiki Sasai Cell Stem Cell
- Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells
- (2013) Asif M. Maroof et al. Cell Stem Cell
- Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development
- (2013) Cory R. Nicholas et al. Cell Stem Cell
- Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness
- (2013) Takayuki Kondo et al. Cell Stem Cell
- Steps Toward Safe Cell Therapy Using Induced Pluripotent Stem Cells
- (2013) Hideyuki Okano et al. CIRCULATION RESEARCH
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- (2013) Monica Nizzardo et al. HUMAN MOLECULAR GENETICS
- Inhibition of mitochondrial fragmentation diminishes Huntington’s disease–associated neurodegeneration
- (2013) Xing Guo et al. JOURNAL OF CLINICAL INVESTIGATION
- Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells
- (2013) Ryoko Araki et al. NATURE
- Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs
- (2013) Changsung Kim et al. NATURE
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- (2013) Madeline A. Lancaster et al. NATURE
- Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo
- (2013) Ira Espuny-Camacho et al. NEURON
- Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
- (2013) A. Serio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2013) Maria Sundberg et al. STEM CELLS
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- (2013) Kohei Homma et al. STEM CELLS
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- (2012) Jung-Il Chae et al. ANIMAL REPRODUCTION SCIENCE
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- (2012) Mahru C. An et al. Cell Stem Cell
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- (2012) Adriana Sánchez-Danés et al. EMBO Molecular Medicine
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- (2012) Yosif M. Ganat et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2012) Mason A. Israel et al. NATURE
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- (2012) Yoshiomi Kobayashi et al. PLoS One
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- (2012) Y. Shi et al. Science Translational Medicine
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- (2012) O. Cooper et al. Science Translational Medicine
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- Modeling familial Alzheimer's disease with induced pluripotent stem cells
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- (2011) Yong-Hee Rhee et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2011) Erika Pedrosa et al. JOURNAL OF NEUROGENETICS
- Modelling schizophrenia using human induced pluripotent stem cells
- (2011) Kristen J. Brennand et al. NATURE
- Immunogenicity of induced pluripotent stem cells
- (2011) Tongbiao Zhao et al. NATURE
- Synergistic NGF/B27 Gradients Position Synapses Heterogeneously in 3D Micropatterned Neural Cultures
- (2011) Anja Kunze et al. PLoS One
- SNCA Triplication Parkinson's Patient's iPSC-derived DA Neurons Accumulate α-Synuclein and Are Susceptible to Oxidative Stress
- (2011) Blake Byers et al. PLoS One
- In Situ Genetic Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells Using Engineered Zinc Finger Nucleases
- (2011) Vittorio Sebastiano et al. STEM CELLS
- Micropatterning neural cell cultures in 3D with a multi-layered scaffold
- (2010) Anja Kunze et al. BIOMATERIALS
- A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells
- (2010) Maria C.N. Marchetto et al. CELL
- Differential Modeling of Fragile X Syndrome by Human Embryonic Stem Cells and Induced Pluripotent Stem Cells
- (2010) Achia Urbach et al. Cell Stem Cell
- Stem cell-based strategies for the treatment of type 1 diabetes mellitus
- (2010) Yujie Wen et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats
- (2010) G. Hargus et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
- (2009) Frank Soldner et al. CELL
- Human immature dental pulp stem cells’ contribution to developing mouse embryos: production of human/mouse preterm chimaeras
- (2009) S. A. Siqueira da Fonseca et al. CELL PROLIFERATION
- Genetic Control of Wayward Pluripotent Stem Cells and Their Progeny after Transplantation
- (2009) Maija Kiuru et al. Cell Stem Cell
- Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease
- (2009) Krishanu Saha et al. Cell Stem Cell
- A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog
- (2009) Justin K. Ichida et al. Cell Stem Cell
- Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins
- (2009) Dohoon Kim et al. Cell Stem Cell
- Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins
- (2009) Hongyan Zhou et al. Cell Stem Cell
- Virus-free induction of pluripotency and subsequent excision of reprogramming factors
- (2009) Keisuke Kaji et al. NATURE
- piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
- (2009) Knut Woltjen et al. NATURE
- Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
- (2009) Stuart M Chambers et al. NATURE BIOTECHNOLOGY
- Geron gets green light for human trial of ES cell–derived product
- (2009) Joe Alper NATURE BIOTECHNOLOGY
- Variation in the safety of induced pluripotent stem cell lines
- (2009) Kyoko Miura et al. NATURE BIOTECHNOLOGY
- Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
- (2009) Noemi FUSAKI et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases
- (2009) L. Ye et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector
- (2009) F. Gonzalez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
- (2009) J. Yu et al. SCIENCE
- In vitro differentiation of reprogrammed murine somatic cells into hepatic precursor cells
- (2008) Tobias Cantz et al. BIOLOGICAL CHEMISTRY
- Stem Cells and Drug Discovery: The Beginning of a New Era?
- (2008) Lee L. Rubin CELL
- A Combined Chemical and Genetic Approach for the Generation of Induced Pluripotent Stem Cells
- (2008) Yan Shi et al. Cell Stem Cell
- Induced pluripotent stem cells from a spinal muscular atrophy patient
- (2008) Allison D. Ebert et al. NATURE
- Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
- (2008) M. Wernig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induced Pluripotent Stem Cells Generated Without Viral Integration
- (2008) M. Stadtfeld et al. SCIENCE
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- (2008) J. T. Dimos et al. SCIENCE
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