Antioxidant Functions of the Aryl Hydrocarbon Receptor

The Brassica-derived phytochemical indolo[3,2-b]carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation

(2016) Dagmar Faust et al.   ARCHIVES OF TOXICOLOGY

Studies on oxidants and antioxidants with a brief glance at their relevance to the immune system

(2016) Banafsheh Amir Aslani et al.   LIFE SCIENCES

Simultaneous activation of Nrf2 and elevation of antioxidant compounds for reducing oxidative stress and chronic inflammation in human Alzheimer's disease

(2016) Kedar N. Prasad   MECHANISMS OF AGEING AND DEVELOPMENT

The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance

(2016) A. L. Furfaro et al.   Oxidative Medicine and Cellular Longevity

Frugal chemoprevention: targeting Nrf2 with foods rich in sulforaphane

(2016) Li Yang et al.   SEMINARS IN ONCOLOGY

Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention

(2015) Bryan Harder et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic

(2015) Maria A. O’Connell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Aryl Hydrocarbon Receptor Activation Down-Regulates IL-7 and Reduces Inflammation in a Mouse Model of DSS-Induced Colitis

(2015) Tao Ji et al.   DIGESTIVE DISEASES AND SCIENCES

Regulatory effects of dioxin-like and non-dioxin-like PCBs and other AhR ligands on the antioxidant enzymes paraoxonase 1/2/3

(2015) Hua Shen et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The aryl hydrocarbon receptor suppresses cigarette-smoke-induced oxidative stress in association with dioxin response element (DRE)-independent regulation of sulfiredoxin 1

(2015) Miles Sarill et al.   FREE RADICAL BIOLOGY AND MEDICINE

Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury

(2015) Lihua Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

AntioxidantOpuntia ficus-indicaExtract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes

(2015) Takeshi Nakahara et al.   JOURNAL OF MEDICINAL FOOD

Aryl hydrocarbon receptor is necessary to protect fetal human pulmonary microvascular endothelial cells against hyperoxic injury: Mechanistic roles of antioxidant enzymes and RelB

(2015) Shaojie Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cynaropicrin attenuates UVB-induced oxidative stress via the AhR–Nrf2–Nqo1 pathway

(2015) Kenjiro Takei et al.   TOXICOLOGY LETTERS

Role of the Aryl Hydrocarbon Receptor in Colon Neoplasia

(2015) Guofeng Xie et al.   Cancers

The Aryl Hydrocarbon Receptor: Multitasking in the Immune System

(2014) Brigitta Stockinger et al.   Annual Review of Immunology

Differential expression of the main polycyclic aromatic hydrocarbon responsive genes in the extrahepatic tissues of mice

(2014) Wenyu Miao et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Activation of the Aryl Hydrocarbon Receptor Dampens the Severity of Inflammatory Skin Conditions

(2014) Paola Di Meglio et al.   IMMUNITY

Mice Deficient in the Gene for Cytochrome P450 (CYP)1A1 Are More Susceptible Than Wild-Type to Hyperoxic Lung Injury: Evidence for Protective Role of CYP1A1 Against Oxidative Stress

(2014) Krithika Lingappan et al.   TOXICOLOGICAL SCIENCES

Aryl hydrocarbon receptor-dependent regulation of miR-196a expression controls lung fibroblast apoptosis but not proliferation

(2014) Emelia Hecht et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

ASC-associated inflammation promotes cecal tumorigenesis in aryl hydrocarbon receptor-deficient mice

(2013) Togo Ikuta et al.   CARCINOGENESIS

Acute exposure to 3-methylcholanthrene induces hepatic oxidative stress via activation of the Nrf2/ARE signaling pathway in mice

(2013) Yuanxiang Jin et al.   ENVIRONMENTAL TOXICOLOGY

Aryl hydrocarbon receptor and colitis

(2013) Ivan Monteleone et al.   Seminars in Immunopathology

Functional deficiency of aryl hydrocarbon receptor augments oxygen toxicity-induced alveolar simplification in newborn mice

(2013) Binoy Shivanna et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Role of sulfiredoxin as a regulator of peroxiredoxin function and regulation of its expression

(2012) Woojin Jeong et al.   FREE RADICAL BIOLOGY AND MEDICINE

High-Resolution Genome-wide Mapping of AHR and ARNT Binding Sites by ChIP-Seq

(2012) Raymond Lo et al.   TOXICOLOGICAL SCIENCES

Regulation of paraoxonase 1 (PON1) in PCB 126-exposed male Sprague Dawley rats

(2012) Hua Shen et al.   TOXICOLOGY LETTERS

From differential induction of UDP-glucuronosyltransferases in rat liver to characterization of responsible ligand-activated transcription factors, and their multilevel crosstalk in humans

(2011) Karl Walter Bock   BIOCHEMICAL PHARMACOLOGY

The Aryl Hydrocarbon Receptor Regulates Mouse Fshr Promoter Activity Through an E-Box Binding Site1

(2011) Indrek Teino et al.   BIOLOGY OF REPRODUCTION

Interactions of the Aryl Hydrocarbon Receptor with Inflammatory Mediators:Beyond CYP1A Regulation

(2011) Jan Vondracek et al.   CURRENT DRUG METABOLISM

Genetic Ablation of the Aryl Hydrocarbon Receptor Causes Cigarette Smoke-induced Mitochondrial Dysfunction and Apoptosis

(2011) Angela Rico de Souza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Ketoconazole as an AhR-Nrf2 Activator in Cultured Human Keratinocytes: The Basis of Its Anti-Inflammatory Effect

(2011) Gaku Tsuji et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Nrf2 protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitis

(2011) Hong Lu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The aryl hydrocarbon receptor (AhR) in the regulation of cell-cell contact and tumor growth

(2010) C. Dietrich et al.   CARCINOGENESIS

Toxic and Chemopreventive Ligands Preferentially Activate Distinct Aryl Hydrocarbon Receptor Pathways: Implications for Cancer Prevention

(2009) S. T. Okino et al.   Cancer Prevention Research

Aryl Hydrocarbon Receptor Facilitates DNA Strand Breaks and 8-Oxo-2′-deoxyguanosine Formation by the Aldo-Keto Reductase Product Benzo[a]pyrene-7,8-dione

(2009) Jong-Heum Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands

(2009) K. Kawajiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Introducing the “TCDD-Inducible AhR-Nrf2 Gene Battery”

(2009) Ronnie L. Yeager et al.   TOXICOLOGICAL SCIENCES

Ah receptor and NF-κB interplay on the stage of epigenome

(2008) Yanan Tian   BIOCHEMICAL PHARMACOLOGY

The Aryl Hydrocarbon Receptor Attenuates Tobacco Smoke-induced Cyclooxygenase-2 and Prostaglandin Production in Lung Fibroblasts through Regulation of the NF-κB Family Member RelB

(2008) Carolyn J. Baglole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phenotype of the Cyp1a1/1a2/1b1(-/-) Triple-Knockout Mouse

(2008) N. Dragin et al.   MOLECULAR PHARMACOLOGY

Abnormal Liver Development and Resistance to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Toxicity in Mice Carrying a Mutation in the DNA-Binding Domain of the Aryl Hydrocarbon Receptor

(2008) Maureen K. Bunger et al.   TOXICOLOGICAL SCIENCES

The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

(2007) Linh P. Nguyen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults

(2007) W OSBURN et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH