Downregulation of TRAF2 Mediates NIK-Induced Pancreatic Cancer Cell Proliferation and Tumorigenicity

Protein Kinase D1 Maintains the Epithelial Phenotype by Inducing a DNA-Bound, Inactive SNAI1 Transcriptional Repressor Complex

(2012) Ligia I. Bastea et al.   PLoS One

TNFR1-induced activation of the classical NF-κB pathway

(2011) Harald Wajant et al.   FEBS Journal

Constitutive noncanonical NFκB signaling in pancreatic cancer cells

(2010) Catherine E. Wharry et al.   CANCER BIOLOGY & THERAPY

NF-κB inducing kinase: A key regulator in the immune system and in cancer

(2010) Yee Mon Thu et al.   CYTOKINE & GROWTH FACTOR REVIEWS

NIK is involved in constitutive activation of the alternative NF-κB pathway and proliferation of pancreatic cancer cells

(2009) Takashi Nishina et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of cell-cell contacts induces NF-κB via RhoA-mediated activation of protein kinase D1

(2009) Catherine F. Cowell et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Nuclear Factor- B p65/relA Silencing Induces Apoptosis and Increases Gemcitabine Effectiveness in a Subset of Pancreatic Cancer Cells

(2008) X. Pan et al.   CLINICAL CANCER RESEARCH

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling

(2008) Sivakumar Vallabhapurapu et al.   NATURE IMMUNOLOGY

Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK

(2008) Brian J Zarnegar et al.   NATURE IMMUNOLOGY

Is NF-κB a good target for cancer therapy? Hopes and pitfalls

(2008) Véronique Baud et al.   NATURE REVIEWS DRUG DISCOVERY