Article
Engineering, Chemical
Stanislava Ivanova, Velislava Todorova, Stanislav Dyankov, Kalin Ivanov
Summary: In this study, a simple and rapid HPTLC method was developed for the detection of meloxicam and piroxicam. The method showed high sensitivity and could detect the compounds at very low concentrations. It offers a simple, cost-effective, and eco-friendly approach for research or routine quality control purposes.
Article
Biochemistry & Molecular Biology
Marcus Daniel Brandbjerg Bohn Lorensen, Nanna Bjarnholt, Benoit St-Pierre, Sarah Heinicke, Vincent Courdavault, Sarah O'Connor, Christian Janfelt
Summary: This study used mass spectrometry imaging (MSI) techniques to explore the biosynthetic pathway of monoterpene indole alkaloids (MIAs). The results showed that ions corresponding to intermediates of reserpine were localized in different tissues of Rauvolfia tetraphylla. By feeding stable-isotope labeled precursors, it was confirmed that these intermediates were synthesized in planta. In addition, a potential novel dimeric MIA was discovered in leaf tissue of R. tetraphylla.
Article
Food Science & Technology
Yiming Zhang, Jinsheng Yu, Shuyu Lai, Jian Song, Xiaomei Wu, Dingnan Wang, Linjiang Pang, Tingting Chai
Summary: By preparing a self-visualization nanomaterial, rapid detection of histamine in foods can be achieved on the HPTLC platform, allowing for visual or semi-quantitative analysis.
Article
Environmental Sciences
Sonalkunwar Chouhan, Rinkal Mulani, Hafsa Ansari, Gaurang Sindhav, Priyashi Rao, Rakesh M. Rawal, Meenu Saraf, Dweipayan Goswami
Summary: This study proposed a HPTLC-based method to investigate the degradation of thiram by Pseudomonas. The results showed that Pseudomonas otitidis strain TD-8 and Pseudomonas stutzeri strain TD-18 exhibited degradation efficiencies of 81% and 99% respectively towards thiram.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Integrative & Complementary Medicine
Yao Shuai, Zhang Jian-Qing, Hou Jin-Jun, Hu Xiao-Su, Wang Ling, Da Juan, Rao Wei, Wang Dan-Dan, Huang Yong, Wu Wan-Ying, Guo De-An
Summary: A simple and practical HPTLC-QDa method was developed for the robust authentication of Ganoderma lucidum and its confused species, allowing for efficient identification based on characteristic mass spectra.
CHINESE JOURNAL OF NATURAL MEDICINES
(2021)
Article
Multidisciplinary Sciences
Himchan Oh, Ji-Young Oh, Chan Woo Park, Jae-Eun Pi, Jong-Heon Yang, Chi-Sun Hwang
Summary: The authors embed inorganic thin film transistors into stretchable serpentine strings to create highly stretchable and miniaturized electronic circuits. These transistors have superior performance and reliability compared to organic transistors.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Analytical
Syed Dilshad Alam, Mirza Adil Beg, Muralidhararao Bagadi, Marcello Locatelli, Zeid A. Alothman, Mohd Mustaqeem, Imran Ali
Summary: Berberine was extracted from Berberis vulgaris, Berberis aquifolium, and Hydrastis canadensis using ethanol and water (70:30, v/v). The extracted berberine was characterized using UV-visible and Fourier-transform infrared spectroscopy. Thin-layer chromatography and high-performance liquid chromatography (HPLC) methods were both employed for the separation and identification of berberine, and showed different applications. The extracted berberine exhibited better activity in treating Leishmaniosis compared to the standard drug Amphotericin B.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Physics, Applied
Haoqi Liang, Jiupeng Cui, Zhihao Yu, Huabin Sun, Heming Wei, Rozalina Zakaria, Binhong Li, Jie Wu, Yong Xu, Chee Leong Tan
Summary: The feasibility of a high-performance ultraviolet photodetector based on a thin layer DPPT-TT organic material is experimentally demonstrated. The device shows excellent performance in terms of absorption, external quantum efficiency, and spectral responsivity. The design of the hole-blocking layer and the stepped structure at the bottom contact is crucial for improving the device's responsivity.
APPLIED PHYSICS LETTERS
(2022)
Article
Environmental Sciences
Carolin Riegraf, Georg Reifferscheid, Liat Moscovici, Dror Shakibai, Henner Hollert, Shimshon Belkin, Sebastian Buchinger
Summary: Over the past two decades, effect-directed analysis (EDA) has become increasingly important as a screening tool for tracking the biological effects of environmental organic micro-pollutants. By combining high-performance thin-layer chromatography (HPTLC) with effect-based methods (EBMs), it is possible to detect various active components in environmental samples efficiently.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Materials Science, Ceramics
Chao Yin, Tiandong Zhang, Bowen Zhang, Changhai Zhang, Qingguo Chi
Summary: In this study, antiferroelectric PbZrO3 films with excellent energy storage properties were prepared and systematically studied on different substrates using the sol-gel process. The results showed that the prepared M-LNO-PZO thin film exhibited high energy storage density and charge-discharge efficiency, as well as good stability under a wide range of working temperatures.
CERAMICS INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Radoslaw Lukasz Gwarda, Tadeusz Henryk Dzido
Summary: High-performance layer electrochromatography (HPLEC) combines the advantages of overpressured-layer chromatography (OPLC) and pressurized planar electrochromatography (PPEC) while overcoming some of their limitations. HPLEC equipment can work in various modes and enable analysis with an electroosmotic effect directed against the hydrodynamic flow. Reversed-polarization HPLEC is advantageous for the analysis of anionic compounds, providing faster and more selective separation compared to OPLC.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Food Science & Technology
Gloria Dominguez-Rodriguez, Merichel Plaza, Maria Luisa Marina
Summary: Alkaline hydrolysis is the most efficient method to recover NEPs from fruit peels, and cherimoya peel extracts contain the richest antioxidant NEPs.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Biochemical Research Methods
Nicolai Baetz, Louisa Rothe, Vanessa Wirzberger, Bernd Sures, Torsten C. Schmidt, Jochen Tuerk
Summary: The study combines YMEES with HPTLC for simultaneous detection of estrogenic, androgenic, and gestagenic effects. The spraying approach showed higher sensitivity and precision compared to immersion for tested hormones.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Physics, Applied
Md Mehedi Hasan, Mohit, Jinbaek Bae, Eisuke Tokumitsu, Hye-Yong Chu, Sung Chul Kim, Jin Jang
Summary: This study presents a solution-processed ZnO thin-film transistor with improved ferroelectric performance in Hf0.5Zr0.5O2 using a triple layer of ZrOx/HZO/AlOx. Experimental results confirm the high performance of the ferroelectric ZnO TFT, opening opportunities for large area electronics on glass.
APPLIED PHYSICS LETTERS
(2021)
Article
Nanoscience & Nanotechnology
Min Seong Kim, Hyung Tae Kim, Hyukjoon Yoo, Dong Hyun Choi, Jeong Woo Park, Tae Sang Kim, Jun Hyung Lim, Hyun Jae Kim
Summary: This study suggests that introducing an oxygen scavenger layer (OSL) in a-IGZO TFT can significantly improve its electrical characteristics and stability, especially at low temperatures. The enhancement is mainly attributed to the presence of hafnium (Hf) in the OSL, which absorbs oxygen ions to address interface issues between the front channel and OSL.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Review
Chemistry, Multidisciplinary
Nirjhar Bhattacharyya, Uttpal Anand, Ravi Kumar, Mimosa Ghorai, Tariq Aftab, Niraj Kumar Jha, Anushka Upamali Rajapaksha, Jochen Bundschuh, Elza Bontempi, Abhijit Dey
Summary: The use of CRISPR technology allows for the modification of plants to better remediate soil contaminated with toxic metals. This technique has been successfully applied to various crops and has identified genes related to metal absorption and tolerance. However, the efficacy of CRISPR technology is influenced by multiple factors.
ENVIRONMENTAL CHEMISTRY LETTERS
(2023)
Article
Plant Sciences
Samapika Nandy, Saynati Mandal, Santosh Kumar Gupta, Uttpal Anand, Mimosa Ghorai, Avinash Mundhra, Md Habibur Rahman, Puja Ray, Sicon Mitra, Durga Ray, Milan Kumar Lal, Rahul Kumar Tiwari, Potshangbam Nongdam, Devendra Kumar Pandey, Mahipal S. Shekhawat, Niraj Kumar Jha, Saurabh Kumar Jha, Manoj Kumar, Radha, Javad Sharifi-Rad, Abhijit Dey
Summary: Global agricultural demand and fluctuating climatic conditions have severely impacted crop productivity and caused inflation in the agricultural market. Plants have their own molecular and signaling mechanisms to combat drought stress, with polyamine signaling playing a major role. Polyamine metabolism pathways are correlated with various plant responses, such as seed germination, plant growth, defense, hormonal regulation, stress tolerance, and crop yield. Recent transcriptomic and metabolomic studies have enhanced our understanding of stress-induced biochemical and molecular alterations in plants.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Review
Green & Sustainable Science & Technology
Anirban Goutam Mukherjee, Kaviyarasi Renu, Abilash Valsala Gopalakrishnan, Vishnu Priya Veeraraghavan, Sathishkumar Vinayagam, Soraya Paz-Montelongo, Abhijit Dey, Balachandar Vellingiri, Alex George, Harishkumar Madhyastha, Raja Ganesan
Summary: Heavy metal and metalloid poisoning in the environment and food, such as cadmium, lead, mercury, tin, manganese, aluminium, arsenic, antimony, and selenium, poses a severe threat to human health and ecological system. Accurate detection of even trace quantities of these toxic elements is of utmost importance to understand their risk. Several traditional and advanced technologies, including atomic absorption spectrometry (AAS), spectrofluorimetry, inductively coupled plasma spectrometry, e-tongues, electrochemical aptasensors, Raman spectroscopy, and fluorescence sensors, have proven highly beneficial in quantifying these elements in food and dietary supplements.
Review
Biotechnology & Applied Microbiology
Devendra Kumar Pandey, Kajal Katoch, Tuyelee Das, Madhumita Majumder, Kuldeep Dhama, Abhijit Bhagwan Mane, Abilash Valsala Gopalakrishnan, Abhijit Dey
Summary: The genus Plumbago, also known as leadwort, produces a secondary metabolite called plumbagin which has multiple pharmaceutical properties. This review explores the biotechnological innovations used to produce plumbagin and the benefits of modern biotechnological techniques in this process. Large-scale in vitro propagation is necessary to conserve natural populations and optimize plant and metabolite production.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Review
Immunology
Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Sandra Kannampuzha, Reshma Murali, Arunraj Namachivayam, Raja Ganesan, Kaviyarasi Renu, Abhijit Dey, Balachandar Vellingiri, D. S. Prabakaran
Summary: COVID-19 has potential detrimental effects on the male reproductive system, with evidence suggesting sexual transmission of the virus. Testicular cells express a high level of ACE2 receptor, facilitating viral entry. COVID-19 may lead to testicular dysfunction and oxidative stress. This study highlights the impact of COVID-19 on male reproductive system and raises unanswered questions about its link to men's health and fertility.
Review
Immunology
Sandra Kannampuzha, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Reshma Murali, Arunraj Namachivayam, Kaviyarasi Renu, Abhijit Dey, Balachandar Vellingiri, Harishkumar Madhyastha, Raja Ganesan
Summary: Lung cancer is a major cause of cancer-related deaths. The altered metabolism of cancer cells results in changes in metabolite concentrations, which can be used to identify distinct metabolic patterns for cancer detection. Understanding and analyzing the variations in metabolites can provide early biomarkers and insights into the progression and type of lung cancer.
Review
Microbiology
Sandra Kannampuzha, Abilash Valsala Gopalakrishnan, Hafiza Padinharayil, Reema Rose Alappat, Kavya V. V. Anilkumar, Alex George, Abhijit Dey, Balachandar Vellingiri, Harishkumar Madhyastha, Raja Ganesan, Thiyagarajan Ramesh, Rama Jayaraj, D. S. Prabakaran
Summary: Infection with viruses, bacteria, and parasites is responsible for about 8-17% of global cancer burden, with one in every five malignancies being caused by an infectious pathogen. Eleven major pathogens are believed to aid in oncogenesis. It is important to identify potential human carcinogens and understand the pathways they induce to effectively prevent and control pathogen-driven cancers. This review focuses on major onco-pathogens, the types of cancer they cause, and the altered pathways leading to cancer progression.
Review
Plant Sciences
Potshangbam Nongdam, David G. G. Beleski, Leimapokpam Tikendra, Abhijit Dey, Vanlalrinchhani Varte, Soumaya EL Merzougui, Vania M. M. Pereira, Patricia R. R. Barros, Wagner A. A. Vendrame
Summary: Orchids are highly valued in the floricultural industry for their stunning flowers and therapeutic properties. However, excessive commercial collection and habitat destruction have led to the depletion of orchid resources, making conservation measures crucial. Conventional propagation methods are unable to meet the demand for ornamental orchids, but in vitro orchid propagation using temporary immersion system (TIS) offers a promising solution with lower production costs and potential for automation.
Review
Biochemistry & Molecular Biology
Nilanjan Ghosh, Leena Chacko, Hiranmoy Bhattacharya, Jayalakshmi Vallamkondu, Sagnik Nag, Abhijit Dey, Tanushree Karmakar, P. Hemachandra Reddy, Ramesh Kandimalla, Saikat Dewanjee
Summary: Diabetes mellitus (DM) and cardiovascular complications often occur together, creating a challenging situation. The development of diabetic cardiomyopathy (DCM) involves complex pathophysiological pathways at the metabolic and molecular level, leading to structural and functional alterations of the heart. Glucagon-like peptide-1 (GLP-1) analogues and sodium-glucose cotransporter-2 (SGLT-2) inhibitors have shown promising results in improving cardiovascular outcomes in diabetes. This article highlights the pathways contributing to DCM and discusses potential future therapies.
Review
Biochemistry & Molecular Biology
Hafiza Padinharayil, Jinsu Varghese, Mithun Chacko John, Golgodu Krishnamurthy Rajanikant, Cornelia M. Wilson, Minnatallah Al-Yozbaki, Kaviyarasi Renu, Saikat Dewanjee, Rupa Sanyal, Abhijit Dey, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Alex George
Summary: Continuous revision of the histologic and stage-wise classification of lung cancer by the World Health Organization (WHO) supports therapeutic advances and accurate diagnosis. Cancer epidemiologic data provide helpful information for cancer prevention and management. Global cancer mortality projections indicate that cancer will become the leading cause of death, particularly non-small cell lung cancer (NSCLC) which accounts for a significant portion of lung cancers. Early diagnosis and proper management play crucial roles in NSCLC therapies. Advanced techniques, such as immune checkpoint inhibitors (ICIs) and targeted molecular therapies, have improved the treatment of late-stage NSCLC. However, the improvement of cancer biomarkers and the development of prospective studies are needed for better therapeutic outcomes.
Article
Environmental Sciences
Pracheta Pal, Uttpal Anand, Suchismita Chatterjee Saha, Suresh Sundaramurthy, Emmanuel Sunday Okeke, Manoj Kumar, Radha, Elza Bontempi, Emidio Albertini, Abhijit Dey, Francesco Di Maria
Summary: In conjunction with global climate change, progressive ocean warming, and acclivity in pollution and anthro-pogenic eutrophication, the incidence of harmful algal blooms (HABs) and cyanobacterial harmful algal blooms (CHABs) continue to expand in distribution, frequency, and magnitude. Algal bloom-related toxins have been implicated in human health disorders and ecological dysfunction and are detrimental to the national and global economy. Biomonitoring programs based on traditional monitoring protocols were characterised by some lim-itations that can be efficiently overdone using the CRISPR/Cas technology.
ENVIRONMENTAL RESEARCH
(2023)
Article
Agricultural Engineering
Mahesh Kumar Badhepuri, M. Manokari, M. Cokul Raj, Phanikanth Jogam, Abhijit Dey, Mohammad Faisal, Abdulrahman A. Alatar, Nirmal Joshee, Nageswara Rao Singisala, Mahipal S. Shekhawat
Summary: A novel and effective direct shoot regeneration technique was developed for the medicinal plant Coleus forskohlii. Meta-Topolin was found to be more efficient than BAP in promoting direct organogenesis. The regeneration process showed distinct phases of shoot formation. The developed protocol can be used for the commercial production of C. forskohlii.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Review
Biochemistry & Molecular Biology
Uttpal Anand, Abhijit Dey, Arvind K. Singh Chandel, Rupa Sanyal, Amarnath Mishra, Devendra Kumar Pandey, Valentina De Falco, Arun Upadhyay, Ramesh Kandimalla, Anupama Chaudhary, Jaspreet Kaur Dhanjal, Saikat Dewanjee, Jayalakshmi Vallamkondu, Jose M. Perez de la Lastra
Summary: Cancer is a deadly disease characterized by uncontrolled cell proliferation and the formation of aggressive malignancies. In recent years, advances in molecular understanding have led to the development of new therapeutic approaches such as targeted drug therapy and immunotherapy. Despite the potential of these treatments, chemotherapy remains a commonly used option due to its effectiveness in advanced-stage malignancies. This report reviews the current advancements in chemotherapy and discusses the emerging role of targeted therapies in improving clinical outcomes for cancer patients.
Article
Biochemistry & Molecular Biology
Manoj M. Gadewar, G. K. Prashanth, Prabhu Chandra Mishra, Ghulam Md Ashraf, Majed N. Almashjary, Steve Harakeh, Vijay Upadhye, Abhijit Dey, Pallavi Singh, Niraj Kumar Jha, Saurabh Kumar Jha
Summary: This study evaluated the antioxidant, antidiabetic, and anti-hyperlipidaemic activity of methanolic fruit extract of Solanum indicum in streptozotocin-induced diabetic rats. The results showed that the fruit extract significantly reduced blood glucose levels and inhibited the activity of α-amylase and α-glycosidase. It also decreased cholesterol and triglyceride levels in the blood and prevented oxidative stress associated with type II diabetes.
CURRENT ISSUES IN MOLECULAR BIOLOGY
(2023)
Article
Plant Sciences
Madhvi Parasher, Devendra Kumar Pandey, R. K. Manhas
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
