Intravenous adenovirus expressing a multi-specific, single-domain antibody neutralizing TcdA and TcdB protects mice fromClostridium difficileinfection

Burden of Clostridium difficile Infection in the United States

(2015) Fernanda C. Lessa et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of Toxemia in Patients with Clostridium difficile Infection

(2015) Hua Yu et al.   PLoS One

Adenovirus Vector Expressing Stx1/Stx2-Neutralizing Agent Protects Piglets Infected with Escherichia coli O157:H7 against Fatal Systemic Intoxication

(2014) Abhineet S. Sheoran et al.   INFECTION AND IMMUNITY

A Novel Multivalent, Single-Domain Antibody Targeting TcdA and TcdB Prevents Fulminant Clostridium difficile Infection in Mice

(2014) Zhiyong Yang et al.   JOURNAL OF INFECTIOUS DISEASES

Prolonged Prophylactic Protection from Botulism with a Single Adenovirus Treatment Promoting Serum Expression of a VHH-Based Antitoxin Protein

(2014) Jean Mukherjee et al.   PLoS One

A Single VHH-Based Toxin-Neutralizing Agent and an Effector Antibody Protect Mice against Challenge with Shiga Toxins 1 and 2

(2013) Jacqueline M. Tremblay et al.   INFECTION AND IMMUNITY

Long-Term Follow-Up of Colonoscopic Fecal Microbiota Transplant for Recurrent Clostridium difficile Infection

(2012) Lawrence J Brandt et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

MBX-500, a Hybrid Antibiotic withIn VitroandIn VivoEfficacy against Toxigenic Clostridium difficile

(2012) Michelle M. Butler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Chimeric Toxin Vaccine Protects against Primary and Recurrent Clostridium difficile Infection

(2012) Haiying Wang et al.   INFECTION AND IMMUNITY

Protection Against Clostridium difficile Infection With Broadly Neutralizing Antitoxin Monoclonal Antibodies

(2012) Andre J. Marozsan et al.   JOURNAL OF INFECTIOUS DISEASES

Systematic Review of Intestinal Microbiota Transplantation (Fecal Bacteriotherapy) for Recurrent Clostridium difficile Infection

(2011) Ethan Gough et al.   CLINICAL INFECTIOUS DISEASES

Development and Evaluation of an Ovine Antibody-Based Platform for Treatment of Clostridium difficile Infection

(2011) April Roberts et al.   INFECTION AND IMMUNITY

Mouse Relapse Model of Clostridium difficile Infection

(2011) Xingmin Sun et al.   INFECTION AND IMMUNITY

A randomized, double-blind, placebo-controlled pilot study to assess the ability of rifaximin to prevent recurrent diarrhoea in patients with Clostridium difficile infection

(2011) K. W. Garey et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Fidaxomicin versus Vancomycin forClostridium difficileInfection

(2011) Thomas J. Louie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adenovirus-based vaccination against Clostridium difficile toxin A allows for rapid humoral immunity and complete protection from toxin A lethal challenge in mice

(2011) Sergey S. Seregin et al.   VACCINE

Treatment with Monoclonal Antibodies againstClostridium difficileToxins

(2010) Israel Lowy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Specific immuno capturing of the Staphylococcal superantigen toxic-shock syndrome toxin-1 in plasma

(2009) Hendrik Adams et al.   BIOTECHNOLOGY AND BIOENGINEERING

Distinct ribotypes and rates of antimicrobial drug resistance in Clostridium difficile from Shanghai and Stockholm

(2009) H. Huang et al.   CLINICAL MICROBIOLOGY AND INFECTION

Antibody-Enhanced, Fc Gamma Receptor-Mediated Endocytosis of Clostridium difficile Toxin A

(2009) X. He et al.   INFECTION AND IMMUNITY

Adenovirus-Mediated Delivery of an Anti-V Antigen Monoclonal Antibody Protects Mice against a Lethal Yersinia pestis Challenge

(2009) C. Sofer-Podesta et al.   INFECTION AND IMMUNITY

Recurrent Clostridium difficile infection: A review of risk factors, treatments, and outcomes

(2009) Stuart Johnson   JOURNAL OF INFECTION

Single domain antibodies: promising experimental and therapeutic tools in infection and immunity

(2009) Janusz Wesolowski et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

A rapid protocol for construction and production of high-capacity adenoviral vectors

(2009) Lorenz Jager et al.   Nature Protocols

A DNA vaccine targeting the receptor-binding domain of Clostridium difficile toxin A

(2009) David F. Gardiner et al.   VACCINE

Serum anti-toxin B antibody correlates with protection from recurrent Clostridium difficile infection (CDI)

(2009) Brett A. Leav et al.   VACCINE

Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium

(2008) Guilin Yang et al.   BMC MICROBIOLOGY

Treatment ofClostridium difficileInfection

(2008) Dale N. Gerding et al.   CLINICAL INFECTIOUS DISEASES

Clostridium difficile— More Difficult Than Ever

(2008) Ciarán P. Kelly et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic delivery of an anti-RSV antibody to protect against pulmonary infection with RSV

(2008) Davor Skaricic et al.   VIROLOGY

Rapid/Sustained Anti-anthrax Passive Immunity Mediated by Co-administration of Ad/AAV

(2007) Bishnu P De et al.   MOLECULAR THERAPY