Development and Evaluation of an Ovine Antibody-Based Platform for Treatment of Clostridium difficile Infection

Clostridium difficile: from obscurity to superbug

(2016) J.S. Brazier   BRITISH JOURNAL OF BIOMEDICAL SCIENCE

Neutralization ofClostridium difficileToxin A with Single-domain Antibodies Targeting the Cell Receptor Binding Domain

(2011) Greg Hussack et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Management ofClostridium difficileInfection: Thinking Inside and Outside the Box

(2010) Dale N. Gerding et al.   CLINICAL INFECTIOUS DISEASES

The emergence of ‘hypervirulence’ in Clostridium difficile

(2010) Stephen T. Cartman et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Clostridium difficileToxin A Decreases Acetylation of Tubulin, Leading to Microtubule Depolymerization through Activation of Histone Deacetylase 6, and This Mediates Acute Inflammation

(2010) Hyo Jung Nam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of toxin A and toxin B in Clostridium difficile infection

(2010) Sarah A. Kuehne et al.   NATURE

Clostridium difficile infection: epidemiology, risk factors and management

(2010) Ashwin N. Ananthakrishnan   Nature Reviews Gastroenterology & Hepatology

Treatment with Monoclonal Antibodies againstClostridium difficileToxins

(2010) Israel Lowy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bivalent Recombinant Vaccine for Botulinum Neurotoxin Types A and B Based on a Polypeptide Comprising Their Effector and Translocation Domains That Is Protective against the Predominant A and B Subtypes

(2009) C. Shone et al.   INFECTION AND IMMUNITY

Cwp84, a Surface-associated Cysteine Protease, Plays a Role in the Maturation of the Surface Layer of Clostridium difficile

(2009) Jonathan M. Kirby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Clostridium difficile Toxin CDT Induces Formation of Microtubule-Based Protrusions and Increases Adherence of Bacteria

(2009) Carsten Schwan et al.   PLoS Pathogens

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

(2009) Richard A Stabler et al.   GENOME BIOLOGY

Toxin-binding treatment for Clostridium difficile: a review including reports of studies with tolevamer

(2008) Karl Weiss   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Structure and mode of action of clostridial glucosylating toxins: the ABCD model

(2008) Thomas Jank et al.   TRENDS IN MICROBIOLOGY