Neuregulin-1 Regulates Cortical Inhibitory Neuron Dendrite and Synapse Growth through DISC1

Inhibition of parvalbumin-expressing interneurons results in complex behavioral changes

(2015) J A Brown et al.   MOLECULAR PSYCHIATRY

Gamma Rhythms Link Prefrontal Interneuron Dysfunction with Cognitive Inflexibility in Dlx5/6+/− Mice

(2015) Kathleen K.A. Cho et al.   NEURON

Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory–inhibitory synapse formation in the mature cortex

(2015) Saurav Seshadri et al.   Nature Communications

Genetic Labeling Reveals Novel Cellular Targets of Schizophrenia Susceptibility Gene: Distribution of GABA and Non-GABA ErbB4-Positive Cells in Adult Mouse Brain

(2014) J. C. Bean et al.   JOURNAL OF NEUROSCIENCE

Neuregulin-ERBB Signaling in the Nervous System and Neuropsychiatric Diseases

(2014) Lin Mei et al.   NEURON

DISC1 knockdown impairs the tangential migration of cortical interneurons by affecting the actin cytoskeleton

(2014) André Steinecke et al.   Frontiers in Cellular Neuroscience

Dysregulated Expression of Neuregulin-1 by Cortical Pyramidal Neurons Disrupts Synaptic Plasticity

(2014) Amit Agarwal et al.   Cell Reports

Neuregulin1 signaling promotes dendritic spine growth through kalirin

(2013) Michael E. Cahill et al.   JOURNAL OF NEUROCHEMISTRY

Regulation of Spine Formation by ErbB4 in PV-Positive Interneurons

(2013) D.-M. Yin et al.   JOURNAL OF NEUROSCIENCE

Altered parvalbumin basket cell inputs in the dorsolateral prefrontal cortex of schizophrenia subjects

(2013) J R Glausier et al.   MOLECULAR PSYCHIATRY

A Theory of the Transition to Critical Period Plasticity: Inhibition Selectively Suppresses Spontaneous Activity

(2013) Taro Toyoizumi et al.   NEURON

Erbb4 Deletion from Fast-Spiking Interneurons Causes Schizophrenia-like Phenotypes

(2013) Isabel del Pino et al.   NEURON

GABAergic Interneurons Shape the Functional Maturation of the Cortex

(2013) Corentin Le Magueresse et al.   NEURON

A neuregulin 1 transmembrane domain mutation causes imbalanced glutamatergic and dopaminergic receptor expression in mice

(2013) K.A. Newell et al.   NEUROSCIENCE

The ErbB/HER family of protein-tyrosine kinases and cancer

(2013) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Abnormal interneuron development in disrupted-in-schizophrenia-1 L100P mutant mice

(2013) Frankie HF Lee et al.   Molecular Brain

Mechanisms of Gamma Oscillations

(2012) György Buzsáki et al.   Annual Review of Neuroscience

A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins

(2012) Jennifer E. Eykelenboom et al.   HUMAN MOLECULAR GENETICS

Conserved Interneuron-Specific ErbB4 Expression in Frontal Cortex of Rodents, Monkeys, and Humans: Implications for Schizophrenia

(2011) Jörg Neddens et al.   BIOLOGICAL PSYCHIATRY

Neuregulin 1 Promotes Excitatory Synapse Development and Function in GABAergic Interneurons

(2011) A. K. Ting et al.   JOURNAL OF NEUROSCIENCE

Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition

(2011) M E Cahill et al.   MOLECULAR PSYCHIATRY

Neuronal activity is required for the development of specific cortical interneuron subtypes

(2011) Natalia V. De Marco García et al.   NATURE

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Linking neurodevelopmental and synaptic theories of mental illness through DISC1

(2011) Nicholas J. Brandon et al.   NATURE REVIEWS NEUROSCIENCE

Dlx5 and Dlx6 Regulate the Development of Parvalbumin-Expressing Cortical Interneurons

(2010) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling

(2010) Pietro Fazzari et al.   NATURE

Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

(2010) Akiko Hayashi-Takagi et al.   NATURE NEUROSCIENCE

Abnormal neural oscillations and synchrony in schizophrenia

(2010) Peter J. Uhlhaas et al.   NATURE REVIEWS NEUROSCIENCE

Disrupted-in-Schizophrenia-1 expression is regulated by  -site amyloid precursor protein cleaving enzyme-1-neuregulin cascade

(2010) S. Seshadri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resequencing and Association Analysis of the KALRN and EPHB1 Genes And Their Contribution to Schizophrenia Susceptibility

(2010) Itaru Kushima et al.   SCHIZOPHRENIA BULLETIN

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

(2009) Yingwei Mao et al.   CELL

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

(2009) Jessica A. Cardin et al.   NATURE

Identification of high risk DISC1 structural variants with a 2% attributable risk for schizophrenia

(2008) Wenjia Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain

(2008) Jonathan D. Wood et al.   HUMAN MOLECULAR GENETICS

ErbB4-Neuregulin Signaling Modulates Synapse Development and Dendritic Arborization through Distinct Mechanisms

(2008) Daria Krivosheya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

(2008) T. Walsh et al.   SCIENCE