ATP Induces Disruption of Tight Junction Proteins via IL-1 Beta-Dependent MMP-9 Activation of Human Blood-Brain BarrierIn Vitro

Physiopathological Roles of P2X Receptors in the Central Nervous System

(2015) G. Burnstock   CURRENT MEDICINAL CHEMISTRY

Neuroprotective effects of brilliant blue G on the brain following traumatic brain injury in rats

(2015) YONG-CHAO WANG et al.   Molecular Medicine Reports

Role of Matrix Metalloproteinases in the Pathogenesis of Traumatic Brain Injury

(2015) P. M. Abdul-Muneer et al.   MOLECULAR NEUROBIOLOGY

Inflammation and Neuroprotection in Traumatic Brain Injury

(2015) Kara N. Corps et al.   JAMA Neurology

NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes

(2015) Audrey Gustin et al.   PLoS One

3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) disrupts blood-brain barrier integrity through a mechanism involving P2X7 receptors

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The incidence of critical-illness-related-corticosteroid-insufficiency is associated with severity of traumatic brain injury in adult rats

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Ablation of matrix metalloproteinase-9 gene decreases cerebrovascular permeability and fibrinogen deposition post traumatic brain injury in mice

(2014) Nino Muradashvili et al.   METABOLIC BRAIN DISEASE

The two-hit hypothesis for neuroinflammation: role of exogenous ATP in modulating inflammation in the brain

(2014) Bernd L. Fiebich et al.   Frontiers in Cellular Neuroscience

Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast

(2013) P.M. Abdul-Muneer et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Review of Neuroprotection Pharmacology and Therapies in Patients with Acute Traumatic Brain Injury

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Activation of the P2X7receptor induces migration of glial cells by inducing cathepsin B degradation of tissue inhibitor of metalloproteinase 1

(2012) Niamh Murphy et al.   JOURNAL OF NEUROCHEMISTRY

The changing landscape of traumatic brain injury research

(2012) The Lancet Neurology   LANCET NEUROLOGY

Activation of P2X7 Promotes Cerebral Edema and Neurological Injury after Traumatic Brain Injury in Mice

(2012) Donald E. Kimbler et al.   PLoS One

The role of shear stress in Blood-Brain Barrier endothelial physiology

(2011) Luca Cucullo et al.   BMC NEUROSCIENCE

Development of a three-dimensional, all-human in vitro model of the blood–brain barrier using mono-, co-, and tri-cultivation Transwell models

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Mild Stretch-Induced Injury Increases Susceptibility to Interleukin-1β-Induced Release of Matrix Metalloproteinase-9 from Astrocytes

(2011) Hantamalala Ralay Ranaivo et al.   JOURNAL OF NEUROTRAUMA

Novel Treatment Targets for Cerebral Edema

(2011) Brian P. Walcott et al.   Neurotherapeutics

Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury

(2010) Dan Shlosberg et al.   Nature Reviews Neurology

IL-1β induces MMP-9 expression via a Ca2+-dependent CaMKII/JNK/c-JUN cascade in rat brain astrocytes

(2009) Cheng-Ying Wu et al.   GLIA

Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure

(2009) Feng Chen et al.   HEPATOLOGY

Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury

(2009) W. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Interleukin-1β in Early Brain Injury After Subarachnoid Hemorrhage in Mice

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