Role of Matrix Metalloproteinases in the Pathogenesis of Traumatic Brain Injury

Neuroprotective Effects of Angiotensin Receptor Blockers

(2014) Sonia Villapol et al.   AMERICAN JOURNAL OF HYPERTENSION

Increased CD147 (EMMPRIN) expression in the rat brain following traumatic brain injury

(2014) Ming Wei et al.   BRAIN RESEARCH

Inhibition of matrix metalloproteinases-2 and -9 prevents cognitive impairment induced by pneumococcal meningitis in Wistar rats

(2014) Tatiana Barichello et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Ablation of matrix metalloproteinase-9 gene decreases cerebrovascular permeability and fibrinogen deposition post traumatic brain injury in mice

(2014) Nino Muradashvili et al.   METABOLIC BRAIN DISEASE

Interactions of Oxidative Stress and Neurovascular Inflammation in the Pathogenesis of Traumatic Brain Injury

(2014) P. M. Abdul-Muneer et al.   MOLECULAR NEUROBIOLOGY

Is there new hope for therapeutic matrix metalloproteinase inhibition?

(2014) Roosmarijn E. Vandenbroucke et al.   NATURE REVIEWS DRUG DISCOVERY

Time dependent integration of matrix metalloproteinases and their targeted substrates directs axonal sprouting and synaptogenesis following central nervous system injury

(2014) LindaL Phillips et al.   Neural Regeneration Research

Blood Pressure–Lowering Treatment With Candesartan in Patients With Acute Hemorrhagic Stroke

(2014) Mirza Jusufovic et al.   STROKE

Regulation of chondrosarcoma invasion by MMP26

(2014) Xiaoshan Xu et al.   TUMOR BIOLOGY

Genetically encoded FRET-based biosensor for imaging MMP-9 activity

(2013) Michal Stawarski et al.   BIOMATERIALS

Increase ICAM-1 and LFA-1 expression by cerebrospinal fluid of subarachnoid hemorrhage patients: Involvement of TNF-α

(2013) Xin Xie et al.   BRAIN RESEARCH

Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking

(2013) Charles A. Galea et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Role of Microglia and Matrix Metalloproteinases Involvement in Neuroinflammation and Gliomas

(2013) Helen Könnecke et al.   Clinical & Developmental Immunology

Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast

(2013) P.M. Abdul-Muneer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Association between the Cerebral Inflammatory and Matrix Metalloproteinase Responses after Severe Traumatic Brain Injury in Humans

(2013) Derek J. Roberts et al.   JOURNAL OF NEUROTRAUMA

Matrix Metalloproteinase-2 and Metalloproteinase-9 Activities are Associated with Blood–Brain Barrier Dysfunction in an Animal Model of Severe Sepsis

(2013) Felipe Dal-Pizzol et al.   MOLECULAR NEUROBIOLOGY

Delayed Progression of Edema Formation Around a Hematoma Expressing High Levels of VEGF and MMP-9 in a Patient With Traumatic Brain Injury: Case Report

(2013) Tomoya HIROSE et al.   NEUROLOGIA MEDICO-CHIRURGICA

Selective Inhibition of Matrix Metalloproteinase-9 Attenuates Secondary Damage Resulting from Severe Traumatic Brain Injury

(2013) Orr Hadass et al.   PLoS One

Matrix metalloproteinase-2 and -9 as promising benefactors in development, plasticity and repair of the nervous system

(2013) Mieke Verslegers et al.   PROGRESS IN NEUROBIOLOGY

Matrilysin-2 expression in colorectal cancer is associated with overall survival of patients

(2013) Qinglin Hu et al.   TUMOR BIOLOGY

A monoclonal antibody interferes with TIMP-2 binding and incapacitates the MMP-2-activating function of multifunctional, pro-tumorigenic MMP-14/MT1–MMP

(2013) S A Shiryaev et al.   Oncogenesis

The Mechanisms of Cerebral Vascular Dysfunction and Neuroinflammation by MMP-Mediated Degradation of VEGFR-2 in Alcohol Ingestion

(2012) P. M. Abdul Muneer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

In Vivo Processing of CXCL5 (LIX) by Matrix Metalloproteinase (MMP)-2 and MMP-9 Promotes Early Neutrophil Recruitment in IL-1 -Induced Peritonitis

(2012) J. Song et al.   JOURNAL OF IMMUNOLOGY

Aquaporin 4: a player in cerebral edema and neuroinflammation

(2012) Andrew M Fukuda et al.   Journal of Neuroinflammation

MT5-MMP, ADAM-10, and N-Cadherin Act in Concert To Facilitate Synapse Reorganization after Traumatic Brain Injury

(2012) Kelly M. Warren et al.   JOURNAL OF NEUROTRAUMA

Angiotensin II Plays a Critical Role in Alcohol-Induced Cardiac Nitrative Damage, Cell Death, Remodeling, and Cardiomyopathy in a Protein Kinase C/Nicotinamide Adenine Dinucleotide Phosphate Oxidase–Dependent Manner

(2012) Yi Tan et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The inflammatory footprints of alcohol-induced oxidative damage in neurovascular components

(2011) Saleena Alikunju et al.   BRAIN BEHAVIOR AND IMMUNITY

Emerging techniques to treat corneal neovascularisation

(2011) J Menzel-Severing   EYE

Mild Stretch-Induced Injury Increases Susceptibility to Interleukin-1β-Induced Release of Matrix Metalloproteinase-9 from Astrocytes

(2011) Hantamalala Ralay Ranaivo et al.   JOURNAL OF NEUROTRAUMA

Tissue inhibitors of metalloproteinases

(2011) Gillian Murphy   GENOME BIOLOGY

Third generation of matrix metalloprotease inhibitors: Gain in selectivity by targeting the depth of the S1′ cavity

(2010) Laurent Devel et al.   BIOCHIMIE

Selective MMP-inhibition with Ro 28-2653 in acute experimental stroke – a magnetic resonance imaging efficacy study

(2010) S. Nagel et al.   BRAIN RESEARCH

Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments

(2010) James J Donkin et al.   CURRENT OPINION IN NEUROLOGY

TNF-α induces matrix metalloproteinase-9 expression in A549 cells: Role of TNFR1/TRAF2/PKCα-dependent signaling pathways

(2010) I-Ta Lee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways

(2010) Hsi-Lung Hsieh et al.   Journal of Neuroinflammation

Metzincin Proteases and Their Inhibitors: Foes or Friends in Nervous System Physiology?

(2010) S. Rivera et al.   JOURNAL OF NEUROSCIENCE

The role of hypoxia-inducible factor-1α, aquaporin-4, and matrix metalloproteinase-9 in blood-brain barrier disruption and brain edema after traumatic brain injury

(2010) Tetsuhiro Higashida et al.   JOURNAL OF NEUROSURGERY

Matrix Metalloproteinase-9 Expression and Protein Levels after Fluid Percussion Injury in Rats: The Effect of Injury Severity and Brain Temperature

(2010) Feng Jia et al.   JOURNAL OF NEUROTRAUMA

Enhanced Matrix Metalloproteinase Activity in the Spontaneously Hypertensive Rat: VEGFR-2 Cleavage, Endothelial Apoptosis, and Capillary Rarefaction

(2010) Edward D. Tran et al.   JOURNAL OF VASCULAR RESEARCH

Temporal Lobe Epilepsy and Matrix Metalloproteinase 9: A tempting relation but negative genetic association

(2010) Kjell Heuser et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Quantitative analyses of matrix metalloproteinase activity after traumatic brain injury in adult rats

(2009) Takuro Hayashi et al.   BRAIN RESEARCH

Minocycline effects on cerebral edema: Relations with inflammatory and oxidative stress markers following traumatic brain injury in mice

(2009) Shadi Homsi et al.   BRAIN RESEARCH

Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis

(2009) Laetitia Devy et al.   CANCER RESEARCH

Inhibition of VEGF receptor 2 increased cell death of dentate hilar neurons after traumatic brain injury

(2009) Cheol Lee et al.   EXPERIMENTAL NEUROLOGY

Involvement of ROS in BBB dysfunction

(2009) Pamela B. L. Pun et al.   FREE RADICAL RESEARCH

The protective effect of alpha lipoic acid against traumatic brain injury in rats

(2009) Hale Z. Toklu et al.   FREE RADICAL RESEARCH

Cytokines and signaling pathways regulating matrix metalloproteinase-9 (MMP-9) expression in corneal epithelial cells

(2009) Gabriel M. Gordon et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neuroprotective Effects of Overexpressing Tissue Inhibitor of Metalloproteinase TIMP-1

(2009) Emiri Tejima et al.   JOURNAL OF NEUROTRAUMA

Alterations in Blood-Brain Barrier Permeability to Large and Small Molecules and Leukocyte Accumulation after Traumatic Brain Injury: Effects of Post-Traumatic Hypothermia

(2009) George Lotocki et al.   JOURNAL OF NEUROTRAUMA

The Protein Kinase C Activator Phorbol Myristate Acetate Decreases Brain Edema by Aquaporin 4 Downregulation after Middle Cerebral Artery Occlusion in the Rat

(2009) Giovanna Fazzina et al.   JOURNAL OF NEUROTRAUMA

Serum matrix metalloproteinase levels correlate with brain injury in human immunodeficiency virus infection

(2009) Ann B Ragin et al.   JOURNAL OF NEUROVIROLOGY

Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelization and disordered collagen fibrillogenesis

(2009) Themis R. Kyriakides et al.   MATRIX BIOLOGY

Brain volume regulation: osmolytes and aquaporin perspectives

(2009) H. Pasantes-Morales et al.   NEUROSCIENCE

Hypoxia-inducible factor-1α signaling in aquaporin upregulation after traumatic brain injury

(2009) Jamie Y. Ding et al.   NEUROSCIENCE LETTERS

Blood–Brain Barrier Disruption in Humans Is Independently Associated With Increased Matrix Metalloproteinase-9

(2009) Taura L. Barr et al.   STROKE

Agrin Expression during Synaptogenesis Induced by Traumatic Brain Injury

(2008) M. Cristina Falo et al.   JOURNAL OF NEUROTRAUMA

Moderate and severe traumatic brain injury in adults

(2008) Andrew IR Maas et al.   LANCET NEUROLOGY

Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia

(2008) E. Candelario-Jalil et al.   NEUROSCIENCE

Matrix metalloproteinases as modulators of inflammation

(2007) A MANICONE et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Transforming Growth Factor-βs

(2003) Martina Böttner et al.   JOURNAL OF NEUROCHEMISTRY