Neural Circuits on a Chip

Perfused drop microfluidic device for brain slice culture-based drug discovery

(2016) Jing Liu et al.   BIOMEDICAL MICRODEVICES

Asymmetric axonal edge guidance: a new paradigm for building oriented neuronal networks

(2016) Renaud Renault et al.   LAB ON A CHIP

Feed-Forward Propagation of Temporal and Rate Information between Cortical Populations during Coherent Activation in Engineered In Vitro Networks

(2016) Thomas B. DeMarse et al.   Frontiers in Neural Circuits

Microfluidic neurite guidance to study structure-function relationships in topologically-complex population-based neural networks

(2016) Thibault Honegger et al.   Scientific Reports

Multi-electrode array capable of supporting precisely patterned hippocampal neuronal networks

(2015) Tianyi Zhou et al.   BIOMEDICAL MICRODEVICES

Microelectronics, bioinformatics and neurocomputation for massive neuronal recordings in brain circuits with large scale multielectrode array probes

(2015) Alessandro Maccione et al.   BRAIN RESEARCH BULLETIN

Designs and sensing mechanisms of genetically encoded fluorescent voltage indicators

(2015) François St-Pierre et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

High-speed recording of neural spikes in awake mice and flies with a fluorescent voltage sensor

(2015) Y. Gong et al.   SCIENCE

An in vitro method to manipulate the direction and functional strength between neural populations

(2015) Liangbin Pan et al.   Frontiers in Neural Circuits

Barbed channels enhance unidirectional connectivity between neuronal networks cultured on multi electrode arrays

(2015) Joost le Feber et al.   Frontiers in Neuroscience

Combining Microfluidics, Optogenetics and Calcium Imaging to Study Neuronal Communication In Vitro

(2015) Renaud Renault et al.   PLoS One

High Content Image Analysis Identifies Novel Regulators of Synaptogenesis in a High-Throughput RNAi Screen of Primary Neurons

(2014) Thomas J. F. Nieland et al.   PLoS One

Assembly of Functional Three-Dimensional Neuronal Networks on a Microchip

(2014) Zhuo Huang et al.   Small

Tuning the adhesive geometry of neurons: length and polarity control

(2014) Caterina Tomba et al.   Soft Matter

Hybrid multiphoton volumetric functional imaging of large-scale bioengineered neuronal networks

(2014) Hod Dana et al.   Nature Communications

NeuroArray: A Universal Interface for Patterning and Interrogating Neural Circuitry with Single Cell Resolution

(2014) Wei Li et al.   Scientific Reports

Network dynamics of 3D engineered neuronal cultures: a new experimental model for in-vitro electrophysiology

(2014) Monica Frega et al.   Scientific Reports

β-amyloid induces a dying-back process and remote trans-synaptic alterations in a microfluidic-based reconstructed neuronal network

(2014) Bérangére Deleglise et al.   Acta Neuropathologica Communications

Two Cell Circuits of Oriented Adult Hippocampal Neurons on Self-Assembled Monolayers for Use in the Study of Neuronal Communication in a Defined System

(2013) Darin Edwards et al.   ACS Chemical Neuroscience

Short-Term Memory in Networks of Dissociated Cortical Neurons

(2013) M. R. Dranias et al.   JOURNAL OF NEUROSCIENCE

Neural circuits with long-distance axon tracts for determining functional connectivity

(2013) Min D. Tang-Schomer et al.   JOURNAL OF NEUROSCIENCE METHODS

Control of neural network patterning using collagen gel photothermal etching

(2013) Aoi Odawara et al.   LAB ON A CHIP

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Multi-electrode array technologies for neuroscience and cardiology

(2013) Micha E. Spira et al.   Nature Nanotechnology

Toward a self-wired active reconstruction of the hippocampal trisynaptic loop: DG-CA3

(2013) Gregory J. Brewer et al.   Frontiers in Neural Circuits

Physical principles for scalable neural recording

(2013) Adam H. Marblestone et al.   Frontiers in Computational Neuroscience

Millimeter-Sized Neural Building Blocks for 3D Heterogeneous Neural Network Assembly

(2013) Midori Kato-Negishi et al.   Advanced Healthcare Materials

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

(2013) Jasper Akerboom et al.   Frontiers in Molecular Neuroscience

Surface Coating as a Key Parameter in Engineering Neuronal Network Structures In Vitro

(2012) Yi Sun et al.   Biointerphases

Functional connectivity and dynamics of cortical–thalamic networks co-cultured in a dual compartment device

(2012) Thirukumaran T Kanagasabapathi et al.   Journal of Neural Engineering

Biophysics of microchannel-enabled neuron–electrode interfaces

(2012) Ling Wang et al.   Journal of Neural Engineering

Single Action Potentials and Subthreshold Electrical Events Imaged in Neurons with a Fluorescent Protein Voltage Probe

(2012) Lei Jin et al.   NEURON

Emergent Functional Properties of Neuronal Networks with Controlled Topology

(2012) Emanuele Marconi et al.   PLoS One

Axon diodes for the reconstruction of oriented neuronal networks in microfluidic chambers

(2011) Jean-Michel Peyrin et al.   LAB ON A CHIP

Optogenetics in Neural Systems

(2011) Ofer Yizhar et al.   NEURON

Self-Organizing Circuit Assembly through Spatiotemporally Coordinated Neuronal Migration within Geometric Constraints

(2011) Yi Sun et al.   PLoS One

An Expanded Palette of Genetically Encoded Ca2+ Indicators

(2011) Y. Zhao et al.   SCIENCE

Synapse microarray identification of small molecules that enhance synaptogenesis

(2011) Peng Shi et al.   Nature Communications

Axon guidance of rat cortical neurons by microcontact printed gradients

(2010) Rita Fricke et al.   BIOMATERIALS

Neuronal Density Determines Network Connectivity and Spontaneous Activity in Cultured Hippocampus

(2010) Miriam Ivenshitz et al.   JOURNAL OF NEUROPHYSIOLOGY

Building and manipulating neural pathways with microfluidics

(2010) Yevgeny Berdichevsky et al.   LAB ON A CHIP

Soft lithography for micro- and nanoscale patterning

(2010) Dong Qin et al.   Nature Protocols

Nanofiber Membranes with Controllable Microwells and Structural Cues and Their Use in Forming Cell Microarrays and Neuronal Networks

(2010) Jingwei Xie et al.   Small

Network plasticity in cortical assemblies

(2008) Michela Chiappalone et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Caged neuron MEA: A system for long-term investigation of cultured neural network connectivity

(2008) Jonathan Erickson et al.   JOURNAL OF NEUROSCIENCE METHODS

Microfluidics and multielectrode array-compatible organotypic slice culture method

(2008) Yevgeny Berdichevsky et al.   JOURNAL OF NEUROSCIENCE METHODS

Novel MEA platform with PDMS microtunnels enables the detection of action potential propagation from isolated axons in culture

(2008) Bradley J. Dworak et al.   LAB ON A CHIP

Colloid-guided assembly of oriented 3D neuronal networks

(2008) Sophie Pautot et al.   NATURE METHODS

Logic gates come to life

(2008) Fred Wolf et al.   Nature Physics

Reliable neuronal logic devices from patterned hippocampal cultures

(2008) Ofer Feinerman et al.   Nature Physics

Development of input connections in neural cultures

(2008) J. Soriano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shaping Embodied Neural Networks for Adaptive Goal-directed Behavior

(2008) Zenas C. Chao et al.   PLoS Computational Biology