Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NFκB Pathway Suppression

Pioglitazone alleviates inflammation in diabetic mice fed a high-fat diet via inhibiting advanced glycation end-product-induced classical macrophage activation

(2016) Xian Jin et al.   FEBS Journal

Pleiotropic Benefits of Metformin: Macrophage Targeting Its Anti-inflammatory Mechanisms: Figure 1

(2015) Yuichi Hattori et al.   DIABETES

Metformin affects the features of a human hepatocellular cell line (HepG2) by regulating macrophage polarization in a co-culture microenviroment

(2015) Miaojiao Chen et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

AMPK Activation Inhibits Expression of Proinflammatory Mediators Through Downregulation of PI3K/p38 MAPK and NF-κB Signaling in Murine Macrophages

(2015) Bee-Piao Huang et al.   DNA AND CELL BIOLOGY

Attenuation of the macrophage inflammatory activity by TiO2 nanotubes via inhibition of MAPK and NF-κB pathways

(2015) Anisoara Cimpean et al.   International Journal of Nanomedicine

Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway

(2015) Xian Jin et al.   Biomed Research International

Metformin Inhibits Monocyte-to-Macrophage Differentiation via AMPK-Mediated Inhibition of STAT3 Activation: Potential Role in Atherosclerosis

(2015) Sathish Babu Vasamsetti et al.   DIABETES

Macrophage Functions in Atherosclerosis

(2014) Iris Zeller et al.   CIRCULATION RESEARCH

Metformin Suppresses Lipopolysaccharide (LPS)-induced Inflammatory Response in Murine Macrophages via Activating Transcription Factor-3 (ATF-3) Induction

(2014) Juyoung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Macrophage Polarization in Infectious and Inflammatory Diseases

(2014) Adam C. Labonte et al.   MOLECULES AND CELLS

Macrophage subsets in atherosclerosis

(2014) Giulia Chinetti-Gbaguidi et al.   Nature Reviews Cardiology

Metformin affects macrophages’ phenotype and improves the activity of glutathione peroxidase, superoxide dismutase, catalase and decreases malondialdehyde concentration in a partially AMPK-independent manner in LPS-stimulated human monocytes/macrophages

(2014) Łukasz Bułdak et al.   Pharmacological Reports

Dynamic Aspects of Macrophage Polarization during Atherosclerosis Progression and Regression

(2014) Michael Peled et al.   Frontiers in Immunology

Role of advanced glycation end products in cellular signaling

(2014) Christiane Ott et al.   Redox Biology

Monocyte–macrophage polarization balance in pre-diabetic individuals

(2013) Gian Paolo Fadini et al.   ACTA DIABETOLOGICA

5′-AMP–Activated Protein Kinase–Activating Transcription Factor 1 Cascade Modulates Human Monocyte–Derived Macrophages to Atheroprotective Functions in Response to Heme or Metformin

(2013) Xinyi Wan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

An unbalanced monocyte polarisation in peripheral blood and bone marrow of patients with type 2 diabetes has an impact on microangiopathy

(2013) G. P. Fadini et al.   DIABETOLOGIA

AGE-LDL Activates Toll Like Receptor 4 Pathway and Promotes Inflammatory Cytokines Production in Renal Tubular Epithelial Cells

(2013) Ao Cheng et al.   International Journal of Biological Sciences

Metformin inhibits inflammatory response via AMPK–PTEN pathway in vascular smooth muscle cells

(2012) Sun Ae Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Advanced Glycation End Products and Diabetic Cardiovascular Disease

(2012) Anand Prasad et al.   Cardiology in Review

Metformin Inhibits Advanced Glycation End Products (AGEs)-induced Renal Tubular Cell Injury by Suppressing Reactive Oxygen Species Generation via Reducing Receptor for AGEs (RAGE) Expression

(2012) Y. Ishibashi et al.   HORMONE AND METABOLIC RESEARCH

Astragalus membranaceus Inhibits Inflammation via Phospho-P38 Mitogen-Activated Protein Kinase (MAPK) and Nuclear Factor (NF)-κB Pathways in Advanced Glycation End Product-Stimulated Macrophages

(2012) Qiaojing Qin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Monocyte and Macrophage Dynamics During Atherogenesis

(2011) Klaus Ley et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cellular and molecular mechanisms of metformin: an overview

(2011) Benoit Viollet et al.   CLINICAL SCIENCE

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

(2011) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM