The Adenosinergic System in Diabetic Retinopathy

Role of Microglia Adenosine A2AReceptors in Retinal and Brain Neurodegenerative Diseases

(2014) Ana R. Santiago et al.   MEDIATORS OF INFLAMMATION

Adenosine A2A Receptor Up-Regulates Retinal Wave Frequency via Starburst Amacrine Cells in the Developing Rat Retina

(2014) Pin-Chien Huang et al.   PLoS One

Association between Related Purine Metabolites and Diabetic Retinopathy in Type 2 Diabetic Patients

(2014) Jianfei Xia et al.   International Journal of Endocrinology

Potential roles of adenosine deaminase-2 in diabetic retinopathy

(2013) Nehal M. Elsherbiny et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Modulation of p75NTR prevents diabetes- and proNGF-induced retinal inflammation and blood–retina barrier breakdown in mice and rats

(2013) Barbara A. Mysona et al.   DIABETOLOGIA

Antagonistic Interaction between Adenosine A2A Receptors and Na+/K+-ATPase- 2 Controlling Glutamate Uptake in Astrocytes

(2013) M. Matos et al.   JOURNAL OF NEUROSCIENCE

Adenosine and Dopamine Receptors Coregulate Photoreceptor Coupling via Gap Junction Phosphorylation in Mouse Retina

(2013) H. Li et al.   JOURNAL OF NEUROSCIENCE

ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy

(2013) Nehal M. Elsherbiny et al.   LIFE SCIENCES

BDNF protects retinal neurons from hyperglycemia through the TrkB/ERK/MAPK pathway

(2013) YU LIU et al.   Molecular Medicine Reports

Effect of Diabetes/Hyperglycemia on the Rat Retinal Adenosinergic System

(2013) Joana Vindeirinho et al.   PLoS One

Neurotrophins and Neurotrophin Receptors in Proliferative Diabetic Retinopathy

(2013) Ahmed M. Abu El-Asrar et al.   PLoS One

Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives

(2013) Rafael Simó et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Global Prevalence and Major Risk Factors of Diabetic Retinopathy

(2012) J. W. Y. Yau et al.   DIABETES CARE

Nucleoside transporters: biological insights and therapeutic applications

(2012) Jung-Suk Choi et al.   Future Medicinal Chemistry

Deletion of Ecto-5'-Nucleotidase (CD73) Reveals Direct Action Potential-Dependent Adenosine Release

(2012) B. P. Klyuch et al.   JOURNAL OF NEUROSCIENCE

Contribution of TNF receptor 1 to retinal neural cell death induced by elevated glucose

(2012) G.N. Costa et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Elevated glucose concentration changes the content and cellular localization of AMPA receptors in the retina but not in the hippocampus

(2012) A.F. Castilho et al.   NEUROSCIENCE

A2A Adenosine Receptor (A2AAR) as a Therapeutic Target in Diabetic Retinopathy

(2011) Ahmed S. Ibrahim et al.   AMERICAN JOURNAL OF PATHOLOGY

Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1

(2011) Katherine E. Trueblood et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Molecular Biology of Nucleoside Transporters and their Distributions and Functions in the Brain

(2011) Fiona E. Parkinson et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Adenosine Augments IL-10 Production by Microglial Cells through an A2B Adenosine Receptor-Mediated Process

(2011) B. Koscso et al.   JOURNAL OF IMMUNOLOGY

Purinergic signaling involved in Müller cell function in the mammalian retina

(2011) Antje Wurm et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA Activity

(2011) Jae-Geun Lee et al.   Diabetes & Metabolism Journal

High glucose and interleukin-1β downregulate interleukin-1 type I receptor (IL-1RI) in retinal endothelial cells by enhancing its degradation by a lysosome-dependent mechanism

(2010) Célia Aveleira et al.   CYTOKINE

TNF-  Signals Through PKC /NF- B to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability

(2010) C. A. Aveleira et al.   DIABETES

Diabetic retinopathy

(2010) Ning Cheung et al.   LANCET

High glucose and oxidative/nitrosative stress conditions induce apoptosis in retinal endothelial cells by a caspase-independent pathway

(2009) Ermelindo C. Leal et al.   EXPERIMENTAL EYE RESEARCH

Effects of resveratrol on nucleotide degrading enzymes in streptozotocin-induced diabetic rats

(2009) Roberta Schmatz et al.   LIFE SCIENCES

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

Immunocytochemical localization of NTPDases1 and 2 in the neural retina of mouse and zebrafish

(2009) María Jimena Ricatti et al.   SYNAPSE

Purinergic signaling in special senses

(2009) Gary D. Housley et al.   TRENDS IN NEUROSCIENCES

Diabetes changes ionotropic glutamate receptor subunit expression level in the human retina

(2008) Ana R. Santiago et al.   BRAIN RESEARCH

Purinergic receptor activation inhibits osmotic glial cell swelling in the diabetic rat retina

(2008) Antje Wurm et al.   EXPERIMENTAL EYE RESEARCH

High glucose changes extracellular adenosine triphosphate levels in rat retinal cultures

(2008) G. Costa et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

(2008) György Haskó et al.   NATURE REVIEWS DRUG DISCOVERY

Nucleotides in ocular secretions: Their role in ocular physiology

(2008) Almudena Crooke et al.   PHARMACOLOGY & THERAPEUTICS

Immunological mechanisms in the pathogenesis of diabetic retinopathy

(2008) Anthony P. Adamis et al.   Seminars in Immunopathology

The A3 adenosine receptor: An enigmatic player in cell biology

(2007) Stefania Gessi et al.   PHARMACOLOGY & THERAPEUTICS

Adenosine in the central nervous system: release mechanisms and extracellular concentrations

(2003) Serena Latini et al.   JOURNAL OF NEUROCHEMISTRY