Dysfunction of respiratory muscles in critically ill patients on the intensive care unit

Diaphragm Muscle Fiber Weakness and Ubiquitin–Proteasome Activation in Critically Ill Patients

(2015) Pleuni E. Hooijman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evolution of Diaphragm Thickness during Mechanical Ventilation. Impact of Inspiratory Effort

(2015) Ewan C. Goligher et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Relationship between Autophagy and Ventilator-induced Diaphragmatic Dysfunction

(2015) Ilan Azuelos et al.   ANESTHESIOLOGY

Inhibition of Forkhead BoxO–Specific Transcription Prevents Mechanical Ventilation–Induced Diaphragm Dysfunction

(2015) Ashley J. Smuder et al.   CRITICAL CARE MEDICINE

Measuring diaphragm thickness with ultrasound in mechanically ventilated patients: feasibility, reproducibility and validity

(2015) Ewan C. Goligher et al.   INTENSIVE CARE MEDICINE

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2015

(2015) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Unaffected contractility of diaphragm muscle fibers in humans on mechanical ventilation

(2014) Pleuni E. Hooijman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Diaphragm Fiber Strength Is Reduced in Critically Ill Patients and Restored by a Troponin Activator

(2014) Pleuni E. Hooijman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Phrenic Nerve Stimulation Increases Human Diaphragm Fiber Force after Cardiothoracic Surgery

(2014) Bumsoo Ahn et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sedation Using Propofol Induces Similar Diaphragm Dysfunction and Atrophy during Spontaneous Breathing and Mechanical Ventilation in Rats

(2014) Christian S. Bruells et al.   ANESTHESIOLOGY

Inhibition of the Ubiquitin–Proteasome Pathway Does Not Protect against Ventilator-induced Accelerated Proteolysis or Atrophy in the Diaphragm

(2014) Ashley J. Smuder et al.   ANESTHESIOLOGY

Effects of Controlled Mechanical Ventilation on Sepsis-Induced Diaphragm Dysfunction in Rats

(2014) Karen Maes et al.   CRITICAL CARE MEDICINE

Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction

(2014) Ira J. Smith et al.   FASEB JOURNAL

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(2014) Daolin Tang et al.   MOLECULAR MEDICINE

Recovery of Diaphragm Function following Mechanical Ventilation in a Rodent Model

(2014) Christian S. Bruells et al.   PLoS One

Does IGFR1 inhibition result in increased muscle mass loss in patients undergoing treatment for pancreatic cancer?

(2014) David R. Fogelman et al.   Journal of Cachexia Sarcopenia and Muscle

Muscle wasting disease: a proposal for a new disease classification

(2014) Stefan D. Anker et al.   Journal of Cachexia Sarcopenia and Muscle

Are we closer to having drugs to treat muscle wasting disease?

(2014) John E. Morley et al.   Journal of Cachexia Sarcopenia and Muscle

Muscle wasting: an overview of recent developments in basic research

(2014) Sandra Palus et al.   Journal of Cachexia Sarcopenia and Muscle

Assessing skeletal muscle mass: historical overview and state of the art

(2014) Steven B. Heymsfield et al.   Journal of Cachexia Sarcopenia and Muscle

Diaphragm Dysfunction on Admission to the Intensive Care Unit. Prevalence, Risk Factors, and Prognostic Impact—A Prospective Study

(2013) Alexandre Demoule et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Monitoring of the Respiratory Muscles in the Critically Ill

(2013) Jonne Doorduin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Neuro-ventilatory efficiency during weaning from mechanical ventilation using neurally adjusted ventilatory assist

(2013) H. Rozé et al.   BRITISH JOURNAL OF ANAESTHESIA

Effect of Intermittent Phrenic Nerve Stimulation During Cardiothoracic Surgery on Mitochondrial Respiration in the Human Diaphragm*

(2013) A. Daniel Martin et al.   CRITICAL CARE MEDICINE

Ultrasound in critically ill patients: focus on diaphragm

(2013) Massimo Zambon et al.   INTENSIVE CARE MEDICINE

Sonographic evaluation of the diaphragm in critically ill patients. Technique and clinical applications

(2013) Dimitrios Matamis et al.   INTENSIVE CARE MEDICINE

Time course of diaphragm function recovery after controlled mechanical ventilation in rats

(2013) Debby Thomas et al.   JOURNAL OF APPLIED PHYSIOLOGY

CrossTalk proposal: Mechanical ventilation-induced diaphragm atrophy is primarily due to inactivity

(2013) Scott K. Powers et al.   JOURNAL OF PHYSIOLOGY-LONDON

Prolonged Mechanical Ventilation Alters the Expression Pattern of Angio-neogenetic Factors in a Pre-Clinical Rat Model

(2013) Christian S. Bruells et al.   PLoS One

Diaphragm ultrasound as a predictor of successful extubation from mechanical ventilation

(2013) Ernest DiNino et al.   THORAX

Mitochondrial Dysfunction and Lipid Accumulation in the Human Diaphragm during Mechanical Ventilation

(2012) Martin Picard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Lipid Overload: Trigger or Consequence of Mitochondrial Oxidative Stress in Ventilator-induced Diaphragmatic Dysfunction?

(2012) Emilia Lecuona et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rapid Onset of Specific Diaphragm Weakness in a Healthy Murine Model of Ventilator-induced Diaphragmatic Dysfunction

(2012) Segolene Mrozek et al.   ANESTHESIOLOGY

Proteasome inhibition and ventilator-induced diaphragmatic dysfunction

(2012) Franco Laghi   CRITICAL CARE MEDICINE

Ventilator-induced diaphragmatic vascular dysfunction*

(2012) Ercheng Zhu et al.   CRITICAL CARE MEDICINE

Bortezomib partially protects the rat diaphragm from ventilator-induced diaphragm dysfunction*

(2012) Anouk Agten et al.   CRITICAL CARE MEDICINE

Mechanical ventilation reduces rat diaphragm blood flow and impairs oxygen delivery and uptake*

(2012) Robert T. Davis et al.   CRITICAL CARE MEDICINE

Both high level pressure support ventilation and controlled mechanical ventilation induce diaphragm dysfunction and atrophy

(2012) Matthew B. Hudson et al.   CRITICAL CARE MEDICINE

Titin and diaphragm dysfunction in mechanically ventilated rats

(2012) Hieronymus W. H. van Hees et al.   INTENSIVE CARE MEDICINE

Diaphragm ultrasonography to estimate the work of breathing during non-invasive ventilation

(2012) Emmanuel Vivier et al.   INTENSIVE CARE MEDICINE

Diaphragm muscle atrophy in the mouse after long-term mechanical ventilation

(2012) Huibin Tang et al.   MUSCLE & NERVE

Molecular Response of the Human Diaphragm on Different Modes of Mechanical Ventilation

(2012) Despina Dermitzaki et al.   RESPIRATION

The Calcium Sensitizer Levosimendan Improves Human Diaphragm Function

(2011) Jonne Doorduin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

N-Acetylcysteine protects the rat diaphragm from the decreased contractility associated with controlled mechanical ventilation*

(2011) Anouk Agten et al.   CRITICAL CARE MEDICINE

Diaphragm dysfunction assessed by ultrasonography: Influence on weaning from mechanical ventilation*

(2011) Won Young Kim et al.   CRITICAL CARE MEDICINE

Nuclear factor-κB signaling contributes to mechanical ventilation-induced diaphragm weakness*

(2011) Ashley J. Smuder et al.   CRITICAL CARE MEDICINE

Intrinsic apoptosis in mechanically ventilated human diaphragm: linkage to a novel Fos/FoxO1/Stat3-Bim axis

(2011) Huibin Tang et al.   FASEB JOURNAL

Neurally adjusted ventilatory assist in patients with critical illness-associated polyneuromyopathy

(2011) Daniel Tuchscherer et al.   INTENSIVE CARE MEDICINE

Endurance exercise attenuates ventilator-induced diaphragm dysfunction

(2011) Ashley J. Smuder et al.   JOURNAL OF APPLIED PHYSIOLOGY

Diaphragm Muscle Weakness in an Experimental Porcine Intensive Care Unit Model

(2011) Julien Ochala et al.   PLoS One

The role of myostatin in muscle wasting: an overview

(2011) Yulia Elkina et al.   Journal of Cachexia Sarcopenia and Muscle

Mechanical Ventilation–induced Diaphragm Disuse in Humans Triggers Autophagy

(2010) Sabah N. A. Hussain et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Increased Proteolysis, Myosin Depletion, and Atrophic AKT-FOXO Signaling in Human Diaphragm Disuse

(2010) Sanford Levine et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rapidly Progressive Diaphragmatic Weakness and Injury during Mechanical Ventilation in Humans

(2010) Samir Jaber et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Adaptive Support Ventilation Prevents Ventilator-induced Diaphragmatic Dysfunction in Piglet

(2010) Boris Jung et al.   ANESTHESIOLOGY

Physiologic Response to Changing Positive End-Expiratory Pressure During Neurally Adjusted Ventilatory Assist in Sedated, Critically Ill Adults

(2010) Christina Passath et al.   CHEST

Neurally adjusted ventilatory assist in patients recovering spontaneous breathing after acute respiratory distress syndrome: Physiological evaluation*

(2010) Nicolas Terzi et al.   CRITICAL CARE MEDICINE

Measurement of monocytic HLA-DR (mHLA-DR) expression in patients with severe sepsis and septic shock: assessment of immune organ failure

(2010) Joerg C. Schefold   INTENSIVE CARE MEDICINE

Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome

(2010) Laurent Papazian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intensive care unit-acquired weakness (ICUAW) and muscle wasting in critically ill patients with severe sepsis and septic shock

(2010) Joerg C. Schefold et al.   Journal of Cachexia Sarcopenia and Muscle

Granulocyte–Macrophage Colony-stimulating Factor to Reverse Sepsis-associated Immunosuppression

(2009) Christian Meisel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Calpain Activation Contributes to Endotoxin-Induced Diaphragmatic Dysfunction

(2009) Gerald S. Supinski et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Apocynin attenuates diaphragm oxidative stress and protease activation during prolonged mechanical ventilation

(2009) Joseph M. McClung et al.   CRITICAL CARE MEDICINE

Ros-mediated activation of NF-κB and Foxo during muscle disuse

(2009) Stephen L. Dodd et al.   MUSCLE & NERVE

Effects of Acute Administration of Corticosteroids during Mechanical Ventilation on Rat Diaphragm

(2008) Karen Maes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Diaphragmatic Motion Studied by M-Mode Ultrasonography

(2008) Alain Boussuges et al.   CHEST

Titration and Implementation of Neurally Adjusted Ventilatory Assist in Critically Ill Patients

(2008) Lukas Brander et al.   CHEST

Consider delayed immunosuppression into the concept of sepsis

(2008) Joerg C. Schefold et al.   CRITICAL CARE MEDICINE

Rapid Disuse Atrophy of Diaphragm Fibers in Mechanically Ventilated Humans

(2008) Sanford Levine et al.   NEW ENGLAND JOURNAL OF MEDICINE