Antiplasmodial Activity Is an Ancient and Conserved Feature of Tick Defensins

Ixodes ricinus defensins attack distantly-related pathogens

(2015) Miray Tonk et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Robustness of predictions of extremely thermally stable proteins in ancient organisms

(2015) Satoshi Akanuma et al.   EVOLUTION

Molecular characterization of a defensin gene from a hard tick, Dermacentor silvarum

(2015) Juanjuan Wang et al.   Parasites & Vectors

Are ticks venomous animals?

(2014) Alejandro Cabezas-Cruz et al.   Frontiers in Zoology

Identification and partial characterisation of new members of the Ixodes ricinus defensin family

(2014) Miray Tonk et al.   GENE

Experimental Conversion of a Defensin into a Neurotoxin: Implications for Origin of Toxic Function

(2014) Shunyi Zhu et al.   MOLECULAR BIOLOGY AND EVOLUTION

Epistasis Constrains Mutational Pathways of Hemoglobin Adaptation in High-Altitude Pikas

(2014) Danielle M. Tufts et al.   MOLECULAR BIOLOGY AND EVOLUTION

CDD: NCBI's conserved domain database

(2014) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Defensins from the tick Ixodes scapularis are effective against phytopathogenic fungi and the human bacterial pathogen Listeria grayi

(2014) Miray Tonk et al.   Parasites & Vectors

Multitasking antimicrobial peptides in plant development and host defense against biotic/abiotic stress

(2014) Ravinder K. Goyal et al.   PLANT SCIENCE

Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

(2014) Ivan KH Poon et al.   eLife

Plasmodium falciparum encodes a conserved active inhibitor-2 for Protein Phosphatase type 1: perspectives for novel anti-plasmodial therapy

(2013) Aline Fréville et al.   BMC BIOLOGY

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

(2013) Koichiro Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Conservation of Protein Structure over Four Billion Years

(2013) Alvaro Ingles-Prieto et al.   STRUCTURE

Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides

(2013) Kelly C. L. Mulder et al.   Frontiers in Microbiology

The defensin gene family expansion in the tick Ixodes scapularis

(2011) Yanbing Wang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

OPM database and PPM web server: resources for positioning of proteins in membranes

(2011) Mikhail A. Lomize et al.   NUCLEIC ACIDS RESEARCH

Anti-babesial activity of a potent peptide fragment derived from longicin of Haemaphysalis longicornis

(2011) Remil Linggatong Galay et al.   TROPICAL ANIMAL HEALTH AND PRODUCTION

Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology

(2010) W. Delport et al.   BIOINFORMATICS

Analyzing protein structure and function using ancestral gene reconstruction

(2010) Michael J Harms et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Identification and characterization of the parasitic wasp Nasonia defensins: Positive selection targeting the functional region?

(2010) Bin Gao et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Tertiary structure-related activity of tick defensin (persulcatusin) in the taiga tick, Ixodes persulcatus

(2010) Emiko Isogai et al.   EXPERIMENTAL AND APPLIED ACAROLOGY

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

Antimicrobial activity of three tick defensins and four mammalian cathelicidin-derived synthetic peptides against Lyme disease spirochetes and bacteria isolated from the midgut

(2009) Emiko Isogai et al.   EXPERIMENTAL AND APPLIED ACAROLOGY

Drosomycin, an essential component of antifungal defence inDrosophila

(2009) Z-T. Zhang et al.   INSECT MOLECULAR BIOLOGY

Discovery of dual function acridones as a new antimalarial chemotype

(2009) Jane X. Kelly et al.   NATURE

Structure prediction for CASP8 with all-atom refinement using Rosetta

(2009) Srivatsan Raman et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

First divergence time estimate of spiders, scorpions, mites and ticks (subphylum: Chelicerata) inferred from mitochondrial phylogeny

(2008) Ayyamperumal Jeyaprakash et al.   EXPERIMENTAL AND APPLIED ACAROLOGY

Plasmodium falciparum: Development and validation of a measure of intraerythrocytic growth using SYBR Green I in a flow cytometer

(2008) Shinji Izumiyama et al.   EXPERIMENTAL PARASITOLOGY

An Improved General Amino Acid Replacement Matrix

(2008) S. Q. Le et al.   MOLECULAR BIOLOGY AND EVOLUTION

Gene expression, antiparasitic activity, and functional evolution of the drosomycin family

(2008) Caihuan Tian et al.   MOLECULAR IMMUNOLOGY

Porcine β-defensin 2 displays broad antimicrobial activity against pathogenic intestinal bacteria

(2007) Edwin J.A. Veldhuizen et al.   MOLECULAR IMMUNOLOGY