Article
Engineering, Mechanical
Lumin Yang, Renjie Li, Xiaozhu Liao, Tao Li, Yunsong Kong, Xiaoduo Zhao, Rui Wang, Zhengfeng Ma, Zengjie Fan, Yong-min Liang, Shuanhong Ma, Feng Zhou
Summary: Osteoarthritis (OA), caused by articular cartilage degeneration, is closely associated with joint lubrication dysfunction. Injecting biolubricants into the joint cavity is considered an effective strategy for arthritis treatment. In this study, a biocompatible chitosan-based nanoparticles (NPs) biolubricant (CS-PMPC@DS NPs) with dual functions of lubrication and anti-inflammatory effects was developed. By grafting zwitterionic poly-electrolyte brush poly(2-methacryloyloxyethyl phosphorylcholine, PMPC) onto the NPs via atom transfer radical polymerization (ATRP) strategy, and encapsulating the anti-inflammatory drug (diclofenac sodium, DS) in them, the obtained biolubricant exhibited superior lubrication performance in both artificial joint materials and cartilage contacts, showing great potential for OA treatment.
TRIBOLOGY INTERNATIONAL
(2023)
Review
Materials Science, Multidisciplinary
Siew Kei Lau, Wai Fen Yong
Summary: This review discusses the application of various polymers and nanomaterials in the surface modification of membranes, with a focus on the unique properties of zwitterionic polymers. These modified membranes resist foulants through mechanisms such as hydration layer formation and steric repulsion effect.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Chemistry, Applied
Baoluo He, Peng Wang, Biwen Wang, Yixuan Du, Le Ji, Shujuan Liu, Qian Ye, Feng Zhou
Summary: In this study, zwitterionic molecule-functionalized GLM nanodroplets were successfully prepared, showing excellent antibacterial and antifouling properties. The functionalized nanocomposite coating could be synthesized by blending with self-polishing coating. Moreover, ZDS@GLM nanodroplets could endow the PDMS coating with self-healing properties.
PROGRESS IN ORGANIC COATINGS
(2022)
Article
Engineering, Chemical
Xinyu Zhang, Zhenglun Lin, Daoji Wu, Ming Xie, Jingtao Xu, Xian Bao, Xiaoxiang Cheng, Ying Wang, Feiyong Chen
Summary: This research demonstrates the fabrication of a robust antifouling RO membrane using the codeposition of Noria with zwitterionic copolymers. The modified membrane shows improved hydrophilicity, reduced roughness, and lower negative charge, leading to an excellent antifouling property during both simulated and actual water treatment processes.
Article
Chemistry, Physical
Jingqi Niu, Hanhan Wang, Jiao Chen, Xueqian Chen, Xia Han, Honglai Liu
Summary: Inspired by marine mussels, dopamine chemistry and zwitterionic structures were combined to design copolymers with both adhesion and antifouling properties, which can be applied in surface modification and oil-water separation. The copolymers show excellent resistance to protein adsorption and repelling oil attachment, with enhanced performance in water due to the hydrophilic surface.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Nanoscience & Nanotechnology
Xinyu Zhang, Jiayu Tian, Ruiyang Xu, Xiaoxiang Cheng, Xuewu Zhu, Ching Yoong Loh, Kaifang Fu, Ruidong Zhang, Daoji Wu, Huixue Ren, Ming Xie
Summary: Breaking the trade-off between filtration performance and antifouling property, this study proposes a novel design route for thin-film nanocomposite nanofiltration membranes, by grafting well-defined zwitterionic copolymers onto polyamide surfaces. The modified membranes exhibit enhanced hydrophilicity, larger surface area, and thinner polyamide layer, resulting in tripled water permeability while maintaining high rejection rate. The modified membrane also demonstrates exceptional antifouling properties in both static and dynamic fouling tests.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Engineering, Biomedical
Jiandong Han, Kexin Zhang, Qixing Cai, Peng Dong, Daping Quan, Ying Bai
Summary: A novel surface grafting approach using surface radical chain-transfer reaction was developed to enhance the antifouling properties of hydrogel-based biomaterials. The grafting of zwitterionic poly(2-methacryloyloxyethyl phosphorylcholine) brushes onto the surface of poly(2-hydroxyethyl methacrylate-co-glycidyl methacrylate) hydrogel reduced protein adhesion and bacterial attachment. This surface-modified hydrogel shows potential for preventing biofouling in biomedical applications, particularly ophthalmic implants and devices. This approach also provides a universal platform for surface functionalization via thiol-epoxy click chemistry and surface radical chain-transfer reaction.
BIOMEDICAL MATERIALS
(2023)
Article
Engineering, Chemical
Shuo-Hsi Tang, Antoine Venault, Yi-Hsin Liu, Yung Chang
Summary: This study demonstrates the successful grafting of poly(sulfobetaine methacrylate) onto glass surface using dopamine, providing the glass with low water contact angle, fogging and frost resistance, antifouling properties, as well as hemocompatibility. The grafted glass materials showed excellent transparency, inhibited frost formation and efficiently resisted biofouling, making them potential candidates for biomedical applications.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2023)
Article
Environmental Sciences
Xiaojiao Li, Kanupriya Nayak, Manfred Stamm, Bijay P. Tripathi
Summary: A simple methodology for preparing nano-porous polysulfone membranes with zwitterionic functionalized silica nanogels is reported, showing high BSA protein rejection and antifouling properties. The zwitterionic membranes exhibited improved water permeation and dye rejection while maintaining high water uptake and protein rejection rates.
Article
Biochemistry & Molecular Biology
Irish Valerie B. Maggay, Hana Nur Aini, Mary Madelaine G. Lagman, Shuo-Hsi Tang, Ruth R. Aquino, Yung Chang, Antoine Venault
Summary: This study introduces a zwitterionic material to modify polysulfone membranes, reducing fouling and improving permeability. The addition of the copolymer reduces bacterial and blood cell attachment by more than 85% and increases the flux recovery ratio. These zwitterionic membranes have potential biomedical applications.
Article
Polymer Science
Esther Roeven, Luc Scheres, Maarten M. J. Smulders, Han Zuilhof
Summary: This study demonstrates two different routes to synthesize polymer-dendrimer hybrids with advantageous self-assembly properties onto silicon oxide surfaces. The first route yields network-like structures with crosslinked PLL and ZIDs, while a more defined linear PLL-ZID macromolecule is formed through a controlled CuAAC click reaction. The potential use of these hybrids as antifouling coatings and for selective detection of target analytes is confirmed through various testing methods.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Engineering, Chemical
Dao Thi Thanh Huyen, Saikat Sinha Ray, Young -Nam Kwon
Summary: This study focuses on the modification of a commercially available polyamide thin-film composite membrane with a zwitterionic material to enhance its fouling resistance. The modified membrane shows improved salt rejection and reduced permeability compared to the pristine membrane. Fouling tests demonstrate that the modified membrane has a lower fouling ratio and higher recovery ratio. The enhanced antifouling characteristics are attributed to the improved hydrophilicity resulting from the zwitterionic brushes and the salting-in effect.
Article
Materials Science, Ceramics
Eva Krakor, Sven Saniternik, Isabel Gessner, Robert Frohnhoven, Michael Wilhelm, Marco Drexelius, Nurgul Tosun, Ines Neundorf, Sanjay Mathur
Summary: Intensive and overuse of antibiotics have led to a rise in antibiotic resistance globally, creating a demand for alternative treatments. Metal ions like copper, silver, and zinc have been used to inhibit microorganism growth for centuries. This study focuses on the synthesis of metal and oxide nanoparticles immobilized on hollow mesoporous silica capsules (HMSCs) for efficient antimicrobial effects against both Gram-positive and Gram-negative bacteria. The results show promising potential for metal-loaded capsules as antibacterial delivery vehicles, providing sustained bacterial inhibition over several hours.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2022)
Article
Engineering, Chemical
Luyao Deng, Shaolu Li, Yiwen Qin, Longjiang Zhang, Haonan Chen, Zaigong Chang, Yunxia Hu
Summary: The TFC NF membrane grafted with zwitterionic PEI shows enhanced hydration capacity, water permeability, ion selectivity, and antifouling properties compared to other membranes. The zwitterionic PEI mitigates the electrostatic attraction between the membrane surface and protein foulants, resulting in lower flux decline and higher flux recovery, demonstrating improved antifouling performance of the membrane.
JOURNAL OF MEMBRANE SCIENCE
(2021)
Article
Chemistry, Physical
Shifeng Wen, Peng Wang, Li Wang
Summary: This study developed a coating with functionalized silica nanoparticles, showing good antifouling performance in experiments. The removal rate of diatoms adhered on the surface was high after the washing process, and the coating maintained good fouling release properties even after wear testing.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Polymer Science
Zun Wang, Kaimin Chen, Chen Hua, Xuhong Guo
Article
Polymer Science
Qiaoling Wang, Kaimin Chen, Yi Qu, Kai Li, Ying Zhang, Enyu Fu
Article
Polymer Science
Xueqian Zhen, Weizhen Li, Jiaming Wu, Xulong Jin, Jiating Wu, Kaimin Chen, Wenjun Gan
Summary: The study found that the addition of PEI increased the storage modulus, while the presence of DMS-E09 led to a monotonous decrease. The introduction of DMS-E09 lowered the value of T(g), partially offset by the presence of PEI.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Chemistry, Applied
Chen Hua, Kaimin Chen, Zun Wang, Xuhong Guo
PROGRESS IN ORGANIC COATINGS
(2020)
Article
Materials Science, Multidisciplinary
Shulong Wang, Weizhen Li, Xulong Jin, Jiating Wu, Kaimin Chen, Wenjun Gan
Summary: A facile method to fabricate three-dimensional thermal conductive composites with multidimensional fillers was reported in this study. The composite materials showed higher thermal conductivity and electrical insulation performance, with a synergistic effect observed between AgNW and BNNS.
JOURNAL OF MATERIALS SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
Enyu Fu, Kaimin Chen, Qiaoling Wang, Ying Zhang, Nana Yan, Li Liu
Summary: Pickering emulsions, known for their solid emulsifiers and stability, have attracted attention. Salt ions, such as Cl- and ClO4-, can induce stable Pickering emulsions under optimized conditions, while PO43- cannot. Increasing salt concentration above a critical point leads to rapid demulsification of the emulsion.
JOURNAL OF MATERIALS SCIENCE
(2021)
Article
Chemistry, Applied
Li Liu, Yu Zhou, Kaimin Chen, Wenjun Gan, Shaoguo Wen, Bo Wang
Summary: Research on waterborne coatings is rapidly growing worldwide. This study addresses the issues of pigment stabilization and antibacterial function in waterborne coatings by encapsulating the pigment and grafting antibacterial polymers.
Article
Engineering, Chemical
Chen Hua, Ziwei Li, Kaimin Chen, Liang Sun, Liang Yu, Xuhong Guo
Summary: Zwitterionic polymer brushes are widely used as hydrophilic and antifouling materials, but they still exhibit adsorption for proteins and other substances in practical application. In this study, a simple and efficient method was employed to prepare zwitterionic spherical polymer brushes and study their interaction with proteins. The findings have important implications for the development of zwitterionic materials with controllable adsorption and desorption of proteins.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Nana Yan, Qiaoling Wang, Kaimin Chen, Yi Qu, Shaoguo Wen
Summary: In this study, fluorescent nanoparticles with different fluorescent molecules were successfully prepared and their fluorescent properties and stability were investigated. The results showed that these nanoparticles exhibited high sensitivity in the detection of Cu2+ and Fe3+ ions.
Article
Polymer Science
Jing Wang, Jihu Wang, Song Wang, Shaoguo Wen, Kaimin Chen, Chen Xie, Chunping Yuan
Summary: The most notable features of polyurea are its fast reaction, energy-saving, and high efficiency. However, waterborne polyurea (WPUA) with hydrophilic groups has reduced solvent resistance, heat resistance, and mechanical properties. Therefore, the development of high-performance WPUA is necessary. In this study, epoxy-modified waterborne polyurea (WPUAE) emulsions were prepared using epoxy resin as a modifier, improving the comprehensive properties of WPUA.
Article
Polymer Science
Qianqian Zhang, Xueke Zhang, Nana Yan, Kaimin Chen
Summary: In this work, temperature-sensitive PS@PNIPA with controlled PNIPA thickness was applied as the Pickering solid emulsifier. The effect of PNIPA thickness on Pickering emulsion formation was studied and the droplet size could be controlled by PS@PNIPA concentration. The emulsification/demulsification process was reversible and repeatable by changing the temperature. Ibuprofen release rate reached 93% and could be tuned by temperature, showing potential applications in chemical release and related fields.
Article
Polymer Science
Liang Yu, Ziwei Li, Chen Hua, Kaimin Chen, Xuhong Guo
Summary: Loading metal nanoparticles into polymer brushes has attracted much attention in catalysis, but the regulation of catalytic performance still requires improvement. Novel diblock polymer brushes, with different block sequences, were prepared and used as nanoreactors to load silver nanoparticles. The different block sequences affected the conformation and catalytic performance, with PSV@PNIPA-b-PSS@Ag showing the ability to control the amount of exposed AgNPs to regulate the reaction rate through hydrogen bonds and physical crosslinking.
Article
Materials Science, Multidisciplinary
Yu Zhou, Kaimin Chen, Li Liu, Shaoguo Wen, Taijiang Gui
Summary: To solve the problems of low polarity, poor dispersion in water, and easy agglomeration of phthalocyanine pigments in waterborne coating applications, the pigments were encapsulated with a copolymer and further grafted with an antibacterial polymer. The encapsulation improved the dispersion of the pigments in water and their compatibility with the resin. The grafting of the antibacterial polymer enhanced the antibacterial properties of the pigments.
Article
Chemistry, Applied
Xueke Zhang, Kaimin Chen, Ziwei Li, Qianqian Zhang, Chenming Xu, Yue Chang, Shaoguo Wen
Summary: In this study, a functional cationic monomer was combined with conventional monomers to prepare cationic polyacrylate latex by emulsion polymerization. The obtained latexes showed good water resistance and mechanical properties, providing a new solution for practical applications.
JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH
(2023)
Article
Materials Science, Biomaterials
Chen Hua, Kaimin Chen, Xuhong Guo
Summary: Glycoproteins are important in biological activities and disease diagnosis, and a facile and eco-friendly method to fabricate spherical polymer brushes with multiple boronic acid groups for glycoprotein separation has been developed. The material shows fast binding speed and high capacity for glycoproteins under physiological conditions, indicating potential for disease diagnosis.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
