NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors

Structural integration in hypoxia-inducible factors

(2015) Dalei Wu et al.   NATURE

Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3α

(2015) Angela M. Fala et al.   Scientific Reports

Circadian clock control of endocrine factors

(2014) Karen L. Gamble et al.   Nature Reviews Endocrinology

NPAS1 Represses the Generation of Specific Subtypes of Cortical Interneurons

(2014) Amelia Stanco et al.   NEURON

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

Human Variants in the Neuronal Basic Helix-Loop-Helix/Per-Arnt-Sim (bHLH/PAS) Transcription Factor Complex NPAS4/ARNT2 Disrupt Function

(2014) David C. Bersten et al.   PLoS One

Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi–like features

(2013) Amélie Bonnefond et al.   JOURNAL OF CLINICAL INVESTIGATION

Structure and Dimerization Properties of the Aryl Hydrocarbon Receptor PAS-A Domain

(2013) D. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Allosteric inhibition of hypoxia inducible factor-2 with small molecules

(2013) Thomas H Scheuermann et al.   Nature Chemical Biology

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

(2012) N. Huang et al.   SCIENCE

Endogenous and Exogenous Ligands of Aryl Hydrocarbon Receptor: Current State of Art

(2011) Lucie Stejskalova et al.   CURRENT DRUG METABOLISM

Ligand Displaces Heat Shock Protein 90 from Overlapping Binding Sites within the Aryl Hydrocarbon Receptor Ligand-binding Domain

(2011) Anatoly Soshilov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Npas4 Regulates a Transcriptional Program in CA3 Required for Contextual Memory Formation

(2011) K. Ramamoorthi et al.   SCIENCE

Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor

(2011) Michael S. Denison et al.   TOXICOLOGICAL SCIENCES

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Cross-Disorder Genomewide Analysis of Schizophrenia, Bipolar Disorder, and Depression

(2010) Jie Huang et al.   AMERICAN JOURNAL OF PSYCHIATRY

Structural Overview of the Nuclear Receptor Superfamily: Insights into Physiology and Therapeutics

(2010) Pengxiang Huang et al.   Annual Review of Physiology

Mammalian Per-Arnt-Sim Proteins in Environmental Adaptation

(2010) Brian E. McIntosh et al.   Annual Review of Physiology

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Interacting haplotypes at the NPAS3 locus alter risk of schizophrenia and bipolar disorder

(2008) B S Pickard et al.   MOLECULAR PSYCHIATRY

T cells hang in the balance

(2008) Emily A. Stevens et al.   NATURE

Involvement of estrogen-related receptors in transcriptional response to hypoxia and growth of solid tumors

(2008) A. Ao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA