Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery

Epigenetic control of oligodendrocyte development: adding new players to old keepers

(2016) Jia Liu et al.   CURRENT OPINION IN NEUROBIOLOGY

Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice

(2016) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity

(2016) A. Etxeberria et al.   JOURNAL OF NEUROSCIENCE

Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination

(2016) Feng Mei et al.   JOURNAL OF NEUROSCIENCE

Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage

(2016) Sarah Moyon et al.   Cell Reports

Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination

(2015) Jayshree Samanta et al.   NATURE

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

(2015) Fadi J. Najm et al.   NATURE

Update on Disease-Modifying Treatments for Multiple Sclerosis

(2014) Michael D. Carrithers   CLINICAL THERAPEUTICS

Adapting brain metabolism to myelination and long-range signal transduction

(2014) Johannes Hirrlinger et al.   GLIA

A unified cell biological perspective on axon–myelin injury

(2014) Mikael Simons et al.   JOURNAL OF CELL BIOLOGY

Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis

(2014) Feng Mei et al.   NATURE MEDICINE

Pervasive Axonal Transport Deficits in Multiple Sclerosis Models

(2014) Catherine Diamante Sorbara et al.   NEURON

Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons

(2013) Shailender Singh et al.   ACTA NEUROPATHOLOGICA

The role of myelin and oligodendrocytes in axonal energy metabolism

(2013) Aiman S Saab et al.   CURRENT OPINION IN NEUROBIOLOGY

A regenerative approach to the treatment of multiple sclerosis

(2013) Vishal A. Deshmukh et al.   NATURE

Epigenome-wide differences in pathology-free regions of multiple sclerosis–affected brains

(2013) Jimmy L Huynh et al.   NATURE NEUROSCIENCE

A rapid and reproducible assay for modeling myelination by oligodendrocytes using engineered nanofibers

(2013) Seonok Lee et al.   Nature Protocols

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

(2013) Kaylene M. Young et al.   NEURON

Oligodendroglia: metabolic supporters of axons

(2013) Brett M. Morrison et al.   TRENDS IN CELL BIOLOGY

Axon degeneration: Molecular mechanisms of a self-destruction pathway

(2012) Jack T. Wang et al.   JOURNAL OF CELL BIOLOGY

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

Animal models of multiple sclerosis: the good, the bad and the bottom line

(2012) Richard M Ransohoff   NATURE NEUROSCIENCE

Neuroprotection and repair in multiple sclerosis

(2012) Robin J. M. Franklin et al.   Nature Reviews Neurology

Age-dependent fate and lineage restriction of single NG2 cells

(2011) X. Zhu et al.   DEVELOPMENT

Muscarinic receptor subtypes as potential targets to modulate oligodendrocyte progenitor survival, proliferation, and differentiation

(2011) Federica De Angelis et al.   Developmental Neurobiology

Clemastine causes immune suppression through inhibition of extracellular signal-regulated kinase–dependent proinflammatory cytokines

(2011) Pål Johansen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

(2011) Ivana Nikić et al.   NATURE MEDICINE

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

(2011) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Regenerative medicine in multiple sclerosis: Identifying pharmacological targets of adult neural stem cell differentiation

(2011) Jeffrey K. Huang et al.   NEUROCHEMISTRY INTERNATIONAL

Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

(2011) S. Y. C. Chong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Presynaptic m1 muscarinic receptors are necessary for mGluR long-term depression in the hippocampus

(2010) A. Kamsler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease

(2009) E. C. Tallantyre et al.   BRAIN

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

(2009) Bruce D Trapp et al.   LANCET NEUROLOGY

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Clonally expanded plasma cells in the cerebrospinal fluid of MS patients produce myelin‐specific antibodies

(2008) Hans‐Christian von Büdingen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE