Single-cell analysis of transcription kinetics across the cell cycle

Control of Transcript Variability in Single Mammalian Cells

(2015) Nico Battich et al.   CELL

Deterministic Restriction on Pluripotent State Dissolution by Cell-Cycle Pathways

(2015) Kevin Andrew Uy Gonzales et al.   CELL

Bursty Gene Expression in the Intact Mammalian Liver

(2015) Keren Bahar Halpern et al.   MOLECULAR CELL

Single Mammalian Cells Compensate for Differences in Cellular Volume and DNA Copy Number through Independent Global Transcriptional Mechanisms

(2015) Olivia Padovan-Merhar et al.   MOLECULAR CELL

Genome-wide study of mRNA degradation and transcript elongation in Escherichia coli

(2015) H. Chen et al.   Molecular Systems Biology

Combining protein and mRNA quantification to decipher transcriptional regulation

(2015) Heng Xu et al.   NATURE METHODS

Nuclear Retention of mRNA in Mammalian Tissues

(2015) Keren Bahar Halpern et al.   Cell Reports

Transcription factor heterogeneity in pluripotent stem cells: a stochastic advantage

(2014) M.-E. Torres-Padilla et al.   DEVELOPMENT

Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency

(2014) Elsa Abranches et al.   DEVELOPMENT

Dynamic Heterogeneity and DNA Methylation in Embryonic Stem Cells

(2014) Zakary S. Singer et al.   MOLECULAR CELL

Validation of noise models for single-cell transcriptomics

(2014) Dominic Grün et al.   NATURE METHODS

Promoter architecture dictates cell-to-cell variability in gene expression

(2014) Daniel L. Jones et al.   SCIENCE

Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells

(2014) Hiroshi Ochiai et al.   Scientific Reports

Transcription Factors Modulate c-Fos Transcriptional Bursts

(2014) Adrien Senecal et al.   Cell Reports

Kinetic competition during the transcription cycle results in stochastic RNA processing

(2014) Antoine Coulon et al.   eLife

Regulation of Noise in Gene Expression

(2013) Alvaro Sanchez et al.   Annual Review of Biophysics

The Cell-Cycle State of Stem Cells Determines Cell Fate Propensity

(2013) Siim Pauklin et al.   CELL

Biallelic Expression of Nanog Protein in Mouse Embryonic Stem Cells

(2013) Adam Filipczyk et al.   Cell Stem Cell

Single-Cell Analysis Reveals that Expression of Nanog Is Biallelic and Equally Variable as that of Other Pluripotency Factors in Mouse ESCs

(2013) Dina A. Faddah et al.   Cell Stem Cell

A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells

(2013) S. Munoz Descalzo et al.   Molecular Systems Biology

Dynamics extracted from fixed cells reveal feedback linking cell growth to cell cycle

(2013) Ran Kafri et al.   NATURE

Visualizing SNVs to quantify allele-specific expression in single cells

(2013) Marshall J Levesque et al.   NATURE METHODS

Allele-specific detection of single mRNA molecules in situ

(2013) Clinton H Hansen et al.   NATURE METHODS

Measuring mRNA copy number in individual Escherichia coli cells using single-molecule fluorescent in situ hybridization

(2013) Samuel O Skinner et al.   Nature Protocols

Origins and implications of pluripotent stem cell variability and heterogeneity

(2013) Patrick Cahan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Generation and Characterization of a Novel Mouse Embryonic Stem Cell Line with a Dynamic Reporter of Nanog Expression

(2013) Elsa Abranches et al.   PLoS One

Transcript processing and export kinetics are rate-limiting steps in expressing vertebrate segmentation clock genes

(2013) N. P. Hoyle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Determinants and Cellular Constraints in Noisy Gene Expression

(2013) A. Sanchez et al.   SCIENCE

Systematic Identification of Signal-Activated Stochastic Gene Regulation

(2013) G. Neuert et al.   SCIENCE

Live-Cell Visualization of Pre-mRNA Splicing with Single-Molecule Sensitivity

(2013) Robert M. Martin et al.   Cell Reports

Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression

(2013) C. J. Zopf et al.   PLoS Computational Biology

Cell-Cycle Control of Developmentally Regulated Transcription Factors Accounts for Heterogeneity in Human Pluripotent Cells

(2013) Amar M. Singh et al.   Stem Cell Reports

Single-Molecule Imaging of Transcriptionally Coupled and Uncoupled Splicing

(2011) Diana Y. Vargas et al.   CELL

Control of the Embryonic Stem Cell State

(2011) Richard A. Young   CELL

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

General properties of transcriptional time series in Escherichia coli

(2011) Lok-hang So et al.   NATURE GENETICS

Lysogen stability is determined by the frequency of activity bursts from the fate-determining gene

(2010) Chenghang Zong et al.   Molecular Systems Biology

Non-genetic heterogeneity from stochastic partitioning at cell division

(2010) Dann Huh et al.   NATURE GENETICS

Nanog Is the Gateway to the Pluripotent Ground State

(2009) Jose Silva et al.   CELL

Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells

(2009) Tibor Kalmar et al.   PLOS BIOLOGY

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells

(2008) L. V. Sharova et al.   DNA RESEARCH

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS

Single-RNA counting reveals alternative modes of gene expression in yeast

(2008) Daniel Zenklusen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Analytical distributions for stochastic gene expression

(2008) V. Shahrezaei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA