The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations

Nonsense-mediated mRNA decay in humans at a glance

(2016) Tatsuaki Kurosaki et al.   JOURNAL OF CELL SCIENCE

Tm7sf2 may participate in the healing of burn wounds

(2016) NA LEI et al.   Molecular Medicine Reports

The Biology of Proteostasis in Aging and Disease

(2015) Johnathan Labbadia et al.   Annual Review of Biochemistry

A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins

(2015) Joseph L. Goldstein et al.   CELL

Establishment of NE asymmetry—targeting of membrane proteins to the inner nuclear membrane

(2015) Rosemarie Ungricht et al.   CURRENT OPINION IN CELL BIOLOGY

Diffusion and retention are major determinants of protein targeting to the inner nuclear membrane

(2015) Rosemarie Ungricht et al.   JOURNAL OF CELL BIOLOGY

The Torsin Activator LULL1 Is Required for Efficient Growth of Herpes Simplex Virus 1

(2015) Elizabeth M. Turner et al.   JOURNAL OF VIROLOGY

Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways

(2015) Matthew A Mitsche et al.   eLife

Surveillance of Nuclear Pore Complex Assembly by ESCRT-III/Vps4

(2014) Brant M. Webster et al.   CELL

The E3 Ubiquitin Ligase MARCH6 Degrades Squalene Monooxygenase and Affects 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase and the Cholesterol Synthesis Pathway

(2014) N. Zelcer et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum

(2014) Xiaochun Li et al.   NATURE

Protein quality control at the inner nuclear membrane

(2014) Anton Khmelinskii et al.   NATURE

Quality control of inner nuclear membrane proteins by the Asi complex

(2014) O. Foresti et al.   SCIENCE

Lamin B receptor

(2014) Ada L. Olins et al.   Nucleus

LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

(2013) Irina Solovei et al.   CELL

Controlling Cholesterol Synthesis beyond 3-Hydroxy-3-methylglutaryl-CoA Reductase (HMGCR)

(2013) Laura J. Sharpe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arresting a Torsin ATPase Reshapes the Endoplasmic Reticulum

(2013) April E. Rose et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Torsin ATPases by LAP1 and LULL1

(2013) C. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Alternative nuclear transport for cellular protein quality control

(2012) April Rose et al.   TRENDS IN CELL BIOLOGY

Growing sphere of influence: Cdc48/p97 orchestrates ubiquitin-dependent extraction from chromatin

(2012) Nico P. Dantuma et al.   TRENDS IN CELL BIOLOGY

Cholesterol-Dependent Degradation of Squalene Monooxygenase, a Control Point in Cholesterol Synthesis beyond HMG-CoA Reductase

(2011) Saloni Gill et al.   Cell Metabolism

Lamin B Receptor Regulates the Growth and Maturation of Myeloid Progenitors via its Sterol Reductase Domain: Implications for Cholesterol Biosynthesis in Regulating Myelopoiesis

(2011) G. Subramanian et al.   JOURNAL OF IMMUNOLOGY

Reduced Lymphocyte Longevity and Homeostatic Proliferation in Lamin B Receptor-Deficient Mice Results in Profound and Progressive Lymphopenia

(2011) A. M. Verhagen et al.   JOURNAL OF IMMUNOLOGY

Protein quality control in the ER: balancing the ubiquitin checkbook

(2011) Jasper H.L. Claessen et al.   TRENDS IN CELL BIOLOGY

Mutations causing Greenberg dysplasia but not Pelger anomaly uncouple enzymatic from structural functions of a nuclear membrane protein

(2011) Peter Clayton et al.   Nucleus

A classical NLS and the SUN domain contribute to the targeting of SUN2 to the inner nuclear membrane

(2010) Yagmur Turgay et al.   EMBO JOURNAL

Border Control at the Nucleus: Biogenesis and Organization of the Nuclear Membrane and Pore Complexes

(2009) Martin W. Hetzer et al.   DEVELOPMENTAL CELL

The Otubain YOD1 Is a Deubiquitinating Enzyme that Associates with p97 to Facilitate Protein Dislocation from the ER

(2009) Robert Ernst et al.   MOLECULAR CELL

Disruption of the gene encoding 3β-hydroxysterol Δ14-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis

(2008) Anna M. Bennati et al.   FEBS Journal

The lamin B receptor under transcriptional control of C/EBPε is required for morphological but not functional maturation of neutrophils

(2008) Tatiana V. Cohen et al.   HUMAN MOLECULAR GENETICS

One step at a time: endoplasmic reticulum-associated degradation

(2008) Shruthi S. Vembar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pathologic, radiographic and molecular findings in three fetuses diagnosed with HEM/Greenberg skeletal dysplasia

(2008) Anastasia Konstantinidou et al.   PRENATAL DIAGNOSIS