Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain

Deletion of fibroblast growth factor 22 (FGF22) causes a depression-like phenotype in adult mice

(2016) Aislinn J. Williams et al.   BEHAVIOURAL BRAIN RESEARCH

IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via Mitochondria at Hippocampal Synapses

(2016) Neta Gazit et al.   NEURON

Excitability governs neural development in a hippocampal region-specific manner

(2015) Erin M. Johnson-Venkatesh et al.   DEVELOPMENT

Distinct sets of FGF receptors sculpt excitatory and inhibitory synaptogenesis

(2015) A. Dabrowski et al.   DEVELOPMENT

Presynaptic active zones in invertebrates and vertebrates

(2015) F. Ackermann et al.   EMBO REPORTS

Mechanism of Activity-Dependent Cargo Loading via the Phosphorylation of KIF3A by PKA and CaMKIIa

(2015) Sotaro Ichinose et al.   NEURON

Neuronal Activity and CaMKII Regulate Kinesin-Mediated Transport of Synaptic AMPARs

(2015) Frédéric J. Hoerndli et al.   NEURON

Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses

(2015) Bo Zhang et al.   NEURON

Insulin-like growth factor 2 mitigates depressive behavior in a rat model of chronic stress

(2015) Yan-Wei Luo et al.   NEUROPHARMACOLOGY

Evaluating the functional state of adult-born neurons in the adult dentate gyrus of the hippocampus: from birth to functional integration

(2015) Andrea Aguilar-Arredondo et al.   REVIEWS IN THE NEUROSCIENCES

Insulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice

(2014) M. Pascual-Lucas et al.   EMBO Molecular Medicine

Insulin-like Growth Factor-II (IGF-II) and IGF-II Analogs with Enhanced Insulin Receptor-a Binding Affinity Promote Neural Stem Cell Expansion

(2014) Amber N. Ziegler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective synaptic targeting of the excitatory and inhibitory presynaptic organizers FGF22 and FGF7

(2014) A. Terauchi et al.   JOURNAL OF CELL SCIENCE

Neuromuscular synaptogenesis: coordinating partners with multiple functions

(2014) Houssam Darabid et al.   NATURE REVIEWS NEUROSCIENCE

Genetic aspects of autism spectrum disorders: insights from animal models

(2014) Swati Banerjee et al.   Frontiers in Cellular Neuroscience

Generating new neurons to circumvent your fears: the role of IGF signaling

(2013) R. C. Agis-Balboa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cellular and molecular mechanisms underlying presynapse formation

(2013) Poh Hui Chia et al.   JOURNAL OF CELL BIOLOGY

Postsynaptic Density Scaffold SAP102 Regulates Cortical Synapse Development through EphB and PAK Signaling Pathway

(2013) Y. Murata et al.   JOURNAL OF NEUROSCIENCE

Reduced Adult Hippocampal Neurogenesis and Working Memory Deficits in the Dgcr8-Deficient Mouse Model of 22q11.2 Deletion-Associated Schizophrenia Can Be Rescued by IGF2

(2013) Y. Ouchi et al.   JOURNAL OF NEUROSCIENCE

Saltatory remodeling of Hox chromatin in response to rostrocaudal patterning signals

(2013) Esteban O Mazzoni et al.   NATURE NEUROSCIENCE

Synapse maturation by activity-dependent ectodomain shedding of SIRPα

(2013) Anna B Toth et al.   NATURE NEUROSCIENCE

Spartin Regulates Synaptic Growth and Neuronal Survival by Inhibiting BMP-Mediated Microtubule Stabilization

(2013) Minyeop Nahm et al.   NEURON

Enhancement of IGF-2-induced neurite outgrowth by IGF-binding protein-2 and osteoglycin in SH-SY5Y human neuroblastoma cells

(2013) Eun Young Jeong et al.   NEUROSCIENCE LETTERS

Prox1 postmitotically defines dentate gyrus cells by specifying granule cell identity over CA3 pyramidal cell fate in the hippocampus

(2012) T. Iwano et al.   DEVELOPMENT

Regulators of synaptic transmission: Roles in the pathogenesis and treatment of epilepsy

(2012) Pablo M. Casillas-Espinosa et al.   EPILEPSIA

The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling

(2012) J. Chen et al.   GENES & DEVELOPMENT

The axonal transport of mitochondria

(2012) W. M. Saxton et al.   JOURNAL OF CELL SCIENCE

I B Kinase/Nuclear Factor  B-Dependent Insulin-Like Growth Factor 2 (Igf2) Expression Regulates Synapse Formation and Spine Maturation via Igf2 Receptor Signaling

(2012) M. J. Schmeisser et al.   JOURNAL OF NEUROSCIENCE

Gene Expression Profiling of Neural Stem Cells and Their Neuronal Progeny Reveals IGF2 as a Regulator of Adult Hippocampal Neurogenesis

(2012) O. Bracko et al.   JOURNAL OF NEUROSCIENCE

The many faces of insulin-like peptide signalling in the brain

(2012) Ana M. Fernandez et al.   NATURE REVIEWS NEUROSCIENCE

IGF-II Promotes Stemness of Neural Restricted Precursors

(2012) Amber N. Ziegler et al.   STEM CELLS

Endocytic trafficking of neurotrophins in neural development

(2012) Maria Ascano et al.   TRENDS IN CELL BIOLOGY

Wnt Signaling in the Vertebrate Central Nervous System: From Axon Guidance to Synaptic Function

(2012) P. C. Salinas   Cold Spring Harbor Perspectives in Biology

Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca2+-Sensor Synaptotagmin-10

(2011) Peng Cao et al.   CELL

Excitation, inhibition, local oscillations, or large-scale loops: what causes the symptoms of schizophrenia?

(2011) John Lisman   CURRENT OPINION IN NEUROBIOLOGY

A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories

(2011) Roberto Carlos Agis-Balboa et al.   EMBO JOURNAL

The Wnt and BMP Families of Signaling Morphogens at the Vertebrate Neuromuscular Junction

(2011) Juan P. Henríquez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A critical role for IGF-II in memory consolidation and enhancement

(2011) Dillon Y. Chen et al.   NATURE

Multiple Forms of Activity-Dependent Competition Refine Hippocampal Circuits In Vivo

(2011) Masahiro Yasuda et al.   NEURON

The Cerebrospinal Fluid Provides a Proliferative Niche for Neural Progenitor Cells

(2011) Maria K. Lehtinen et al.   NEURON

Cadherin-9 Regulates Synapse-Specific Differentiation in the Developing Hippocampus

(2011) Megan E. Williams et al.   NEURON

Neuronal Activity-Regulated Gene Transcription in Synapse Development and Cognitive Function

(2011) A. E. West et al.   Cold Spring Harbor Perspectives in Biology

Genetics and Cell Biology of Building Specific Synaptic Connectivity

(2010) Kang Shen et al.   Annual Review of Neuroscience

Synaptic organizing complexes

(2010) Tabrez J Siddiqui et al.   CURRENT OPINION IN NEUROBIOLOGY

FGF signalling: diverse roles during early vertebrate embryogenesis

(2010) K. Dorey et al.   DEVELOPMENT

Secreted factors as synaptic organizers

(2010) Erin M. Johnson-Venkatesh et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Distinct FGFs promote differentiation of excitatory and inhibitory synapses

(2010) Akiko Terauchi et al.   NATURE

Retrograde BMP Signaling Controls Synaptic Growth at the NMJ by Regulating Trio Expression in Motor Neurons

(2010) Robin W. Ball et al.   NEURON

Long-Distance Control of Synapse Assembly by Target-Derived NGF

(2010) Nikhil Sharma et al.   NEURON

Neuroligin-2 Deletion Selectively Decreases Inhibitory Synaptic Transmission Originating from Fast-Spiking but Not from Somatostatin-Positive Interneurons

(2009) J. R. Gibson et al.   JOURNAL OF NEUROSCIENCE

Activity-Dependent Regulation of Synapses by Retrograde Messengers

(2009) Wade G. Regehr et al.   NEURON

The State of Synapses in Fragile X Syndrome

(2009) Brad E. Pfeiffer et al.   NEUROSCIENTIST

Developmental axon pruning mediated by BDNF-p75NTR–dependent axon degeneration

(2008) Karun K Singh et al.   NATURE NEUROSCIENCE

A Model for Neuronal Competition During Development

(2008) C. D. Deppmann et al.   SCIENCE