Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis
Authors
Keywords
-
Journal
eLife
Volume 5, Issue -, Pages -
Publisher
eLife Sciences Organisation, Ltd.
Online
2016-02-25
DOI
10.7554/elife.12204
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cancer statistics, 2015
- (2015) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Sestrin2 facilitates death receptor-induced apoptosis in lung adenocarcinoma cells through regulation of XIAP degradation
- (2015) Boxiao Ding et al. CELL CYCLE
- GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2
- (2015) Jiangbin Ye et al. GENES & DEVELOPMENT
- p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb
- (2015) S. Agarwal et al. MOLECULAR CANCER RESEARCH
- Sestrin2 is a leucine sensor for the mTORC1 pathway
- (2015) R. L. Wolfson et al. SCIENCE
- Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains
- (2015) Hanseong Kim et al. Nature Communications
- Sestrin2 inhibits mTORC1 through modulation of GATOR complexes
- (2015) Jeong Sig Kim et al. Scientific Reports
- Sestrins Function as Guanine Nucleotide Dissociation Inhibitors for Rag GTPases to Control mTORC1 Signaling
- (2014) Min Peng et al. CELL
- Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1
- (2014) Seung-Hyun Ro et al. FEBS Journal
- mTORC1-mediated translational elongation limits intestinal tumour initiation and growth
- (2014) William J. Faller et al. NATURE
- Rapamycin Inhibition of Polyposis and Progression to Dysplasia in a Mouse Model
- (2014) Karin M. Hardiman et al. PLoS One
- Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species
- (2014) S.-H. Ro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hepatoprotective role of Sestrin2 against chronic ER stress
- (2014) Hwan-Woo Park et al. Nature Communications
- The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1
- (2014) Lynne Chantranupong et al. Cell Reports
- Sestrins Inhibit mTORC1 Kinase Activation through the GATOR Complex
- (2014) Anita Parmigiani et al. Cell Reports
- Sox9 Induction, Ectopic Paneth Cells, and Mitotic Spindle Axis Defects in Mouse Colon Adenomatous Epithelium Arising From Conditional Biallelic Apc Inactivation
- (2013) Ying Feng et al. AMERICAN JOURNAL OF PATHOLOGY
- Sestrins Orchestrate Cellular Metabolism to Attenuate Aging
- (2013) Jun Hee Lee et al. Cell Metabolism
- The Unfolded Protein Response and Chemical Chaperones Reduce Protein Misfolding and Colitis in Mice
- (2013) Stewart Siyan Cao et al. GASTROENTEROLOGY
- Endothelial PAS Domain Protein 1 Activates the Inflammatory Response in the Intestinal Epithelium to Promote Colitis in Mice
- (2013) Xiang Xue et al. GASTROENTEROLOGY
- Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress
- (2013) R. M. Young et al. GENES & DEVELOPMENT
- mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice
- (2013) Stefan Thiem et al. JOURNAL OF CLINICAL INVESTIGATION
- Nelfinavir and bortezomib inhibit mTOR activity via ATF4-mediated sestrin-2 regulation
- (2013) Ansgar Brüning et al. Molecular Oncology
- Intestinal HIF2 promotes tissue-iron accumulation in disorders of iron overload with anemia
- (2013) E. R. Anderson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Maintenance of Metabolic Homeostasis by Sestrin2 and Sestrin3
- (2012) Jun Hee Lee et al. Cell Metabolism
- Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage
- (2012) Soo Han Bae et al. Cell Metabolism
- Oxidative stress and redox signaling mechanisms of inflammatory bowel disease: updated experimental and clinical evidence
- (2012) Hong Zhu et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth
- (2012) Sergei I. Grivennikov et al. NATURE
- Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells
- (2012) Toran Sanli et al. PLoS One
- Molecular Genetics of Colorectal Cancer
- (2011) Eric R. Fearon Annual Review of Pathology-Mechanisms of Disease
- Crohn's disease: NOD2, autophagy and ER stress converge
- (2011) T. Fritz et al. GUT
- Pathogenesis and biomarkers of carcinogenesis in ulcerative colitis
- (2011) Sigrun Thorsteinsdottir et al. Nature Reviews Gastroenterology & Hepatology
- Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression
- (2010) Eek Joong Park et al. CELL
- A ‘metastasis-prone’ signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics
- (2010) Yi Hong et al. CLINICAL & EXPERIMENTAL METASTASIS
- Inflammation and Colon Cancer
- (2010) Janoš Terzić et al. GASTROENTEROLOGY
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Correction: Modeling Oncogenic Signaling in Colon Tumors by Multidirectional Analyses of Microarray Data Directed for Maximization of Analytical Reliability
- (2010) Magdalena Skrzypczak et al. PLoS One
- Sestrin as a Feedback Inhibitor of TOR That Prevents Age-Related Pathologies
- (2010) J. H. Lee et al. SCIENCE
- The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein
- (2010) Zhaohui Feng et al. TRENDS IN CELL BIOLOGY
- Cross-Species Comparison of Human and Mouse Intestinal Polyps Reveals Conserved Mechanisms in Adenomatous Polyposis Coli (APC)-Driven Tumorigenesis
- (2008) Claudia Gaspar et al. AMERICAN JOURNAL OF PATHOLOGY
- Sestrin 2 Is Not a Reductase for Cysteine Sulfinic Acid of Peroxiredoxins
- (2008) Hyun Ae Woo et al. ANTIOXIDANTS & REDOX SIGNALING
- Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis
- (2008) Veronique Nogueira et al. CANCER CELL
- Mouse models for the study of colon carcinogenesis
- (2008) D. W. Rosenberg et al. CARCINOGENESIS
- XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
- (2008) Arthur Kaser et al. CELL
- p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
- (2008) Andrei V. Budanov et al. CELL
- Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis
- (2008) Umut Ozcan et al. MOLECULAR CELL
- Transcriptional control of human p53-regulated genes
- (2008) Todd Riley et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search