Evolution of an ancient protein function involved in organized multicellularity in animals

Aurora Kinases Phosphorylate Lgl to Induce Mitotic Spindle Orientation in Drosophila Epithelia

(2015) Graham P. Bell et al.   CURRENT BIOLOGY

The Evolution of the GPCR Signaling System in Eukaryotes: Modularity, Conservation, and the Transition to Metazoan Multicellularity

(2014) Alex de Mendoza et al.   Genome Biology and Evolution

Dlg1 controls planar spindle orientation in the neuroepithelium through direct interaction with LGN

(2014) Mehdi Saadaoui et al.   JOURNAL OF CELL BIOLOGY

The Genomic and Cellular Foundations of Animal Origins

(2013) Daniel J. Richter et al.   Annual Review of Genetics

Discs Large Links Spindle Orientation to Apical-Basal Polarity in Drosophila Epithelia

(2013) Dan T. Bergstralh et al.   CURRENT BIOLOGY

Molecular pathways regulating mitotic spindle orientation in animal cells

(2013) M. S. Lu et al.   DEVELOPMENT

Epithelial junctions maintain tissue architecture by directing planar spindle orientation

(2013) Yu-ichiro Nakajima et al.   NATURE

Evolutionary biochemistry: revealing the historical and physical causes of protein properties

(2013) Michael J. Harms et al.   NATURE REVIEWS GENETICS

Divergent evolution of protein conformational dynamics in dihydrofolate reductase

(2013) Gira Bhabha et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors

(2013) M. J. Harms et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulated aggregative multicellularity in a close unicellular relative of metazoa

(2013) Arnau Sebé-Pedrós et al.   eLife

Structure of an Enzyme-Derived Phosphoprotein Recognition Domain

(2012) Christopher A. Johnston et al.   PLoS One

Cell Division Orientation in Animals

(2011) Taryn E. Gillies et al.   CURRENT BIOLOGY

Cell differentiation and morphogenesis in the colony-forming choanoflagellate Salpingoeca rosetta

(2011) Mark J. Dayel et al.   DEVELOPMENTAL BIOLOGY

Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development

(2011) Xavier Morin et al.   DEVELOPMENTAL CELL

Tre1 GPCR Signaling Orients Stem Cell Divisions in the Drosophila Central Nervous System

(2011) Shigeki Yoshiura et al.   DEVELOPMENTAL CELL

Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules

(2011) Jinwei Zhu et al.   EMBO JOURNAL

Robust Spindle Alignment in Drosophila Neuroblasts by Ultrasensitive Activation of Pins

(2011) Nicholas R. Smith et al.   MOLECULAR CELL

Asymmetric cell divisions promote Notch-dependent epidermal differentiation

(2011) Scott E. Williams et al.   NATURE

Asymmetric cell division in land plants and algae: the driving force for differentiation

(2011) Ive De Smet et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Conversion of the enzyme guanylate kinase into a mitotic-spindle orienting protein by a single mutation that inhibits GMP-induced closing

(2011) C. A. Johnston et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Survey of Branch Support Methods Demonstrates Accuracy, Power, and Robustness of Fast Likelihood-based Approximation Schemes

(2011) Maria Anisimova et al.   SYSTEMATIC BIOLOGY

Evolution of the MAGUK protein gene family in premetazoan lineages

(2010) Alex de Mendoza et al.   BMC EVOLUTIONARY BIOLOGY

Analyzing protein structure and function using ancestral gene reconstruction

(2010) Michael J Harms et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Six major steps in animal evolution: are we derived sponge larvae?

(2010) Claus Nielsen   EVOLUTION & DEVELOPMENT

Robustness of Ancestral Sequence Reconstruction to Phylogenetic Uncertainty

(2010) Victor Hanson-Smith et al.   MOLECULAR BIOLOGY AND EVOLUTION

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

Identification of an Aurora-A/PinsLINKER/ Dlg Spindle Orientation Pathway using Induced Cell Polarity in S2 Cells

(2009) Christopher A. Johnston et al.   CELL

Apical/Basal Spindle Orientation Is Required for Neuroblast Homeostasis and Neuronal Differentiation in Drosophila

(2009) Clemens Cabernard et al.   DEVELOPMENTAL CELL

Protein Dynamism and Evolvability

(2009) N. Tokuriki et al.   SCIENCE

The Origins of Multicellularity and the Early History of the Genetic Toolkit For Animal Development

(2008) Antonis Rokas   Annual Review of Genetics

The molecular origins of multicellular transitions

(2008) Antonis Rokas   CURRENT OPINION IN GENETICS & DEVELOPMENT

Evolution of Hormone Signaling in Elasmobranchs by Exploitation of Promiscuous Receptors

(2008) S. M. Carroll et al.   MOLECULAR BIOLOGY AND EVOLUTION