NusG inhibits RNA polymerase backtracking by stabilizing the minimal transcription bubble

Biochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II Arrest

(2016) J. Brooks Crickard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NusG Is a Sequence-specific RNA Polymerase Pause Factor That Binds to the Non-template DNA within the Paused Transcription Bubble

(2016) Alexander V. Yakhnin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of transcribing mammalian RNA polymerase II

(2016) Carrie Bernecky et al.   NATURE

Structures ofE.coliσS-transcription initiation complexes provide new insights into polymerase mechanism

(2016) Bin Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TFE and Spt4/5 open and close the RNA polymerase clamp during the transcription cycle

(2016) Sarah Schulz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts

(2016) N. J. Kramer et al.   SCIENCE

SuhB Associates with Nus Factors To Facilitate 30S Ribosome Biogenesis in Escherichia coli

(2016) Navjot Singh et al.   mBio

Regulation of Transcript Elongation

(2015) Georgiy A. Belogurov et al.   Annual Review of Microbiology

Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble

(2015) Christopher O. Barnes et al.   MOLECULAR CELL

Mechanism of Transcription Termination by RNA Polymerase III Utilizes a Non-template Strand Sequence-Specific Signal Element

(2015) Aneeshkumar G. Arimbasseri et al.   MOLECULAR CELL

The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions

(2015) Shun-ichi Sekine et al.   MOLECULAR CELL

Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble

(2015) Yuhong Zuo et al.   MOLECULAR CELL

Structure of a bacterial RNA polymerase holoenzyme open promoter complex

(2015) Brian Bae et al.   eLife

UvrD facilitates DNA repair by pulling RNA polymerase backwards

(2014) Vitaly Epshtein et al.   NATURE

RNA polymerase pausing and nascent-RNA structure formation are linked through clamp-domain movement

(2014) Pyae P Hein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interactions between RNA polymerase and the "core recognition element" counteract pausing

(2014) I. O. Vvedenskaya et al.   SCIENCE

Mycobacterial RNA Polymerase Requires a U-Tract at Intrinsic Terminators and Is Aided by NusG at Suboptimal Terminators

(2014) A. Czyz et al.   mBio

CBR antimicrobials alter coupling between the bridge helix and the β subunit in RNA polymerase

(2014) Anssi M. Malinen et al.   Nature Communications

Structural Basis of Transcriptional Pausing in Bacteria

(2013) Albert Weixlbaumer et al.   CELL

RNA polymerase and the ribosome: the close relationship

(2013) Katelyn McGary et al.   CURRENT OPINION IN MICROBIOLOGY

Antisense Oligonucleotide-stimulated Transcriptional Pausing Reveals RNA Exit Channel Specificity of RNA Polymerase and Mechanistic Contributions of NusA and RfaH

(2013) Kellie E. Kolb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

X-ray Crystal Structure ofEscherichia coliRNA Polymerase σ70Holoenzyme

(2013) Katsuhiko S. Murakami   JOURNAL OF BIOLOGICAL CHEMISTRY

Phyletic distribution and conservation of the bacterial transcription termination factor Rho

(2013) F. D'Heygere et al.   MICROBIOLOGY-SGM

RNA Polymerase Backtracking in Gene Regulation and Genome Instability

(2012) Evgeny Nudler   CELL

Rho and NusG suppress pervasive antisense transcription in Escherichia coli

(2012) J. M. Peters et al.   GENES & DEVELOPMENT

A Nexus for Gene Expression—Molecular Mechanisms of Spt5 and NusG in the Three Domains of Life

(2012) Finn Werner   JOURNAL OF MOLECULAR BIOLOGY

Nus transcription elongation factors and RNase III modulate small ribosome subunit biogenesis inEscherichia coli

(2012) Mikhail Bubunenko et al.   MOLECULAR MICROBIOLOGY

Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans

(2012) Karen Adelman et al.   NATURE REVIEWS GENETICS

Active site opening and closure control translocation of multisubunit RNA polymerase

(2012) Anssi M. Malinen et al.   NUCLEIC ACIDS RESEARCH

Rho-dependent transcription termination is essential to prevent excessive genome-wide R-loops in Escherichia coli

(2012) J. Krishna Leela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Transcription Initiation

(2012) Y. Zhang et al.   SCIENCE

Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity

(2011) Fuensanta W Martinez-Rucobo et al.   EMBO JOURNAL

σ70-dependent Transcription Pausing in Escherichia coli

(2011) Sarah A. Perdue et al.   JOURNAL OF MOLECULAR BIOLOGY

The β Subunit Gate Loop Is Required for RNA Polymerase Modification by RfaH and NusG

(2011) Anastasia Sevostyanova et al.   MOLECULAR CELL

Termination and antitermination: RNA polymerase runs a stop sign

(2011) Thomas J. Santangelo et al.   NATURE REVIEWS MICROBIOLOGY

E. coli NusG Inhibits Backtracking and Accelerates Pause-Free Transcription by Promoting Forward Translocation of RNA Polymerase

(2010) Kristina M. Herbert et al.   JOURNAL OF MOLECULAR BIOLOGY

Functional regions of the N-terminal domain of the antiterminator RfaH

(2010) Georgiy A. Belogurov et al.   MOLECULAR MICROBIOLOGY

Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif

(2010) Angela Hirtreiter et al.   NUCLEIC ACIDS RESEARCH

Functional analysis of Thermus thermophilus transcription factor NusG

(2010) A. Sevostyanova et al.   NUCLEIC ACIDS RESEARCH

RNA polymerase and transcription elongation factor Spt4/5 complex structure

(2010) B. J. Klein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A NusE:NusG Complex Links Transcription and Translation

(2010) B. M. Burmann et al.   SCIENCE

Cooperation Between Translating Ribosomes and RNA Polymerase in Transcription Elongation

(2010) S. Proshkin et al.   SCIENCE

Complete Structural Model of Escherichia coli RNA Polymerase from a Hybrid Approach

(2010) Natacha Opalka et al.   PLOS BIOLOGY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Two Structurally Independent Domains of E. coli NusG Create Regulatory Plasticity via Distinct Interactions with RNA Polymerase and Regulators

(2009) Rachel Anne Mooney et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulator Trafficking on Bacterial Transcription Units In Vivo

(2009) Rachel A. Mooney et al.   MOLECULAR CELL

Role of the RNA polymerase trigger loop in catalysis and pausing

(2009) Jinwei Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nano positioning system reveals the course of upstream and nontemplate DNA within the RNA polymerase II elongation complex

(2009) Joanna Andrecka et al.   NUCLEIC ACIDS RESEARCH

Mechanism of sequence-specific pausing of bacterial RNA polymerase

(2009) M. L. Kireeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rho directs widespread termination of intragenic and stable RNA transcription

(2009) J. M. Peters et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution

(2009) D. Wang et al.   SCIENCE

Structural basis of transcription inhibition by α-amanitin and implications for RNA polymerase II translocation

(2008) Florian Brueckner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Function of the Bacillus subtilis transcription elongation factor NusG in hairpin-dependent RNA polymerase pausing in the trp leader

(2008) A. V. Yakhnin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Termination Factor Rho and Its Cofactors NusA and NusG Silence Foreign DNA in E. coli

(2008) C. J. Cardinale et al.   SCIENCE