Review
Biology
Sean P. F. Foley, John Scott Parrish
Summary: Pleural space infections have been a well-recognized clinical syndrome for over 4000 years and continue to cause significant morbidity and mortality worldwide. Our understanding of the causative pathophysiology has greatly expanded over the last few decades, as have our treatment options. This paper aims to review recent updates in our understanding of pleural space infections and provide updates on treatment modalities.
Article
Cardiac & Cardiovascular Systems
Amit Chopra, Llewellyn Foulke, Marc A. Judson
Summary: A sarcoidosis associated pleural effusion (SAPE) is a pleural effusion caused by active granulomatous inflammation from sarcoidosis. SAPE commonly occurs at the initial presentation of sarcoidosis or within the first year, with dyspnea being the most common presenting symptom. Clinical features and pleural fluid analysis are essential for diagnosing SAPE. Corticosteroids are the preferred treatment and have rapid effectiveness, with a low rate of recurrence.
RESPIRATORY MEDICINE
(2022)
Article
Biology
Pham Thi Huyen, Meiyu Li, Lei Li, Sike Ma, Yan Zhao, Jing Yan, Zhexiang Wang, Meng Zhao, Xuguo Sun
Summary: This study demonstrates that the multidimensional evaluation of deep learning and entropy weight method provides high accuracy in the complementary diagnosis of pleural effusion diseases. Cell morphology biomarkers WBC, MNC %, PNC %, MTC % have higher clinical value among pleural fluid biomarkers.
COMPUTATIONAL BIOLOGY AND CHEMISTRY
(2021)
Article
Microbiology
Seo-Hee Kim, Eun Lee, Eun-Song Song, Yun-Young Lee
Summary: This study investigated the clinical implications of pleural effusion in children with Mycoplasma pneumoniae pneumonia, revealing that the presence of pleural effusion may indicate a more severe clinical course and poor treatment response. The results could assist in creating therapeutic plans and predicting the clinical course of Mycoplasma pneumoniae pneumonia in children.
Article
Microbiology
Fabio Aguiar-Alves, Hoan N. Le, Vuvi G. Tran, Emmanuelle Gras, Trang T. T. Vu, Oliver X. Dong, Josiane Silva Quetz, Lily Cheng, Li Yu, Bret R. Sellman, Charles K. Stover, Antonio DiGiandomenico, Binh An Diep
Summary: The use of MEDI3902 antibody for prophylactic treatment has been shown to protect rabbits from Pseudomonas aeruginosa infection and reduce lung lesions and bacteremia. Compared to MEDI3902 treatment, rabbits treated with irrelevant control IgG exhibited severe pneumonia and systemic pathophysiological changes. These results suggest that MEDI3902 prophylaxis can decrease the severity of P. aeruginosa ventilator-associated pneumonia.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2022)
Article
Critical Care Medicine
Deirdre B. Fitzgerald, Grant W. Waterer, Charley Budgeon, Ranjan Shrestha, Edward T. Fysh, Sanjeevan Muruganandan, Christopher Stanley, Tajalli Saghaie, Arash Badiei, Calvin Sidhu, Hilman Harryanto, Victor Duong, Maree Azzopardi, David Manners, Norris S. H. Lan, Natalia D. Popowicz, Carolyn J. Peddle-McIntyre, Najib M. Rahman, Catherine A. Read, Ai Ling Tan, Seng Khee Gan, Kevin Murray, Y. C. Gary Lee
Summary: The use of systemic corticosteroids did not show any preliminary benefits in adults with pleural effusions related to pneumonia, including no differences in time to normalization of vital signs, inflammatory markers, or leukocyte counts, as well as no differences in pleural drainage procedures and radiographic outcomes.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Nursing
Eman Arafa Hassan, Suad Elsayed Abdelmotalb Elsaman
Summary: Compliance with the ventilator bundle was found to be associated with a decreased risk of ventilator-associated events (VAEs) occurrence. Mechanically ventilated patients had a lower likelihood of experiencing VAEs when receiving the ventilator bundle.
Article
Critical Care Medicine
Gauthier Blonz, Achille Kouatchet, Nicolas Chudeau, Emmanuel Pontis, Julien Lorber, Anthony Lemeur, Lucie Planche, Jean-Baptiste Lascarrou, Gwenhael Colin
Summary: The study analyzed data from 188 patients hospitalized for severe COVID-19 in ICUs, showing a high incidence of VAP with a significant proportion of enterobacteria, and higher risk in male patients. Complications such as abscess and empyema were not exceptional in VAP cases.
Article
Infectious Diseases
Amira Mohamed, Enas Daef, Amany Nafie, Lamia Shaban, Maggie Ibrahim
Summary: This study aimed to investigate the frequency of carbapenem-resistance and the rates of MDR, XDR, and PDR in CR-GNB infections in VAP. The study found a high presence of carbapenem-resistance genes in the isolates, with bla(NDM) being the most predominant gene. All isolates exhibited high resistance to most antibiotics.
Article
Medicine, General & Internal
Ines Gragueb-Chatti, Herve Hyvernat, Marc Leone, Geoffray Agard, Noemie Peres, Christophe Guervilly, Mohamed Boucekine, Dany Hamidi, Laurent Papazian, Jean Dellamonica, Alexandre Lopez, Sami Hraiech
Summary: In patients with COVID-19 associated respiratory failure, approximately 46% of those who experienced a first episode of VAP had recurrences. These recurrences were mainly relapses and were associated with longer durations of MV and ICU stays, but not with increased mortality.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Pharmacology & Pharmacy
Jiayi Deng, Fanglin Li, Ningjie Zhang, Yanjun Zhong
Summary: Ventilator-associated pneumonia (VAP) is a common acquired infection in the intensive care unit, and COVID-19 patients on mechanical ventilation have a high risk of developing VAP. Prevention is more important than treatment, with measures such as minimizing exposure to mechanical ventilation and early release. Empirical antibiotics are the main treatment, but attention should be paid to the antimicrobial spectrum and duration.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Immunology
Ling Zhu, Yuqiu Hao, Wei Li, Bingqing Shi, Hongna Dong, Peng Gao
Summary: The objective of this study was to use metagenomic next-generation sequencing (mNGS) to profile the bacterial pathogen of pleural infection in aspiration pneumonia for therapeutic decision-making. The results showed that mNGS detection of pleural effusion clarified the microbial spectrum of aspiration pneumonia and allowed for targeted antibiotic administration.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Immunology
Vu Quoc Dat, Lam Minh Yen, Huynh Thi Loan, Vu Dinh Phu, Nguyen Thien Binh, Ronald B. Geskus, Dong Huu Khanh Trinh, Nguyen Thi Hoang Mai, Nguyen Hoan Phu, Nguyen Phu Huong Lan, Tran Phuong Thuy, Nguyen Vu Trung, Nguyen Trung Cap, Dao Tuyet Trinh, Nguyen Thi Hoa, Nguyen Thi Thu Van, Vy Thi Thu Luan, Tran Thi Quynh Nhu, Hoang Bao Long, Nguyen Thi Thanh Ha, Ninh Thi Thanh Van, James Campbell, Ehsan Ahmadnia, Evelyne Kestelyn, Duncan Wyncoll, Guy E. Thwaites, Nguyen Van Hao, Le Thanh Chien, Nguyen Van Kinh, Nguyen Van Vinh Chau, H. Rogier van Doorn, C. Louise Thwaites, Behzad Nadjm
Summary: The study found that continuous cuff pressure control (CPC) using an automated electronic device did not reduce the incidence of ventilator-associated respiratory infection (VARI) in intubated patients compared to intermittent CPC.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Biology
Christina R. MacRosty, Amber Wright, Agathe Ceppe, Sohini Ghosh, A. Cole Burks, Jason A. Akulian
Summary: Malignant pleural effusion is associated with poor prognosis. Resolving pleural fluid accumulation in patients with malignant pleural effusion is associated with a survival benefit, independent of other treatment factors. Understanding the mechanism of fluid resolution and tumor-immune interplay is essential for improved management of this condition.
Article
Medicine, General & Internal
Lubna Almogarry, Alzahra Y. Alradhi, Abdullah Alshamrani
Summary: Pleural effusion is a common presentation of pleural diseases, with the two predominant types in children being exudative and transudative effusions. Bacterial infection is the most prevalent cause of exudative effusion in children. In some cases, it can be difficult to confirm the effusion. We described two patients with similar symptoms who were initially managed as parapneumonic effusion but showed no improvement with antibiotics. After reviewing the cases, it was found that important aspects of the history and examination had been overlooked. Caution should be taken with parapneumonic effusion, and thorough history and examination are necessary for accurate diagnosis. Lymphocytic-predominant effusion without tuberculosis infection should raise concerns for potential malignancy. Early referral should be considered if antibiotic treatment is ineffective.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Nursing
Heather Baid, Jessica Hargreaves
NURSING IN CRITICAL CARE
(2015)
Article
Education, Scientific Disciplines
Heather Baid, Nicky Lambert
NURSE EDUCATION TODAY
(2010)
Article
Nursing
Heather Baid
NURSING IN CRITICAL CARE
(2011)
Editorial Material
Nursing
Heather Baid
NURSING IN CRITICAL CARE
(2018)
Article
Nursing
Heather Baid, Janet Richardson, Julie Scholes, Clair Hebron
Summary: The study aimed to explore the concept of sustainability in critical care practice from the perspective of practitioners, defining it as maintaining financial, environmental, and social resources across all levels of critical care systems. The most significant social process enabling sustainability was identified as satisficing, which allows practitioners to fulfill their sense of normative, responsible, sustainable, and flourishing practice within resource constraints.
NURSING IN CRITICAL CARE
(2021)
Editorial Material
Nursing
Heather Baid, Josef Trapani
NURSING IN CRITICAL CARE
(2021)
Editorial Material
Nursing
Heather Baid, Eleanor Damm
INTENSIVE AND CRITICAL CARE NURSING
(2021)
Article
Education, Scientific Disciplines
Carmen Alvarez-Nieto, Janet Richardson, M. Angeles Navarro-Peran, Naomi Tutticci, Norma Huss, Marie Elf, Anna Anaker, Jennie Aronsson, Heather Baid, Isabel M. Lopez-Medina
Summary: This study investigates the attitudes and awareness of nursing students towards climate change and sustainability, as well as the inclusion of these topics in their curriculum. The results show that nursing students have increasingly positive attitudes towards sustainability and climate change, and recognize the importance of education in these areas. This highlights the need to integrate these competencies into nursing curricula.
NURSE EDUCATION TODAY
(2022)
Editorial Material
Critical Care Medicine
Federico Barbariol, Heather Baid
INTENSIVE CARE MEDICINE
(2023)
Editorial Material
Nursing
Heather Baid, Fredrika Sundberg
NURSING IN CRITICAL CARE
(2023)
Editorial Material
Medicine, General & Internal
Heather Baid, Eleanor Damm, Louise Trent, Forbes McGain
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Meeting Abstract
Nursing
Raymund Vincent Javier, Heather Baid
NURSING IN CRITICAL CARE
(2021)
Review
Anesthesiology
Valentina Della Torre, Flavio E. Nacul, Peter Rosseel, Heather Baid, Kaushik Bhowmick, Piotr Szawarski, Tapas K. Sahoo, Tughan Utku, Adrian Wong, Manu L. N. G. Malbrain
Summary: Human factors and ergonomics (HFE) is a scientific discipline that studies the interrelationship between humans, equipment, and the work environment, with the main goal of optimizing human interaction with the work environment and technical equipment to maximize patient safety and care efficiency. This paper highlights the importance of HFE in assisting intensivists and ICU teams in delivering high-quality care to patients in crisis situations.
ANAESTHESIOLOGY INTENSIVE THERAPY
(2021)
