Antivirulence Bispecific Monoclonal Antibody-Mediated Protection against Pseudomonas aeruginosa Ventilator-Associated Pneumonia in a Rabbit Model

Pseudomonas aeruginosa Ventilator-Associated Pneumonia Rabbit Model for Preclinical Drug Development

(2021) Nhu T.Q. Nguyen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Infectious Diseases Society of America’s 10 × ’20 Initiative (Ten New Systemic Antibacterial Agents FDA-approved by 2020): Is 20 × ’20 a Possibility?

(2019) George H Talbot et al.   CLINICAL INFECTIOUS DISEASES

Neutrophil Extracellular Traps Confine Pseudomonas aeruginosa Ocular Biofilms and Restrict Brain Invasion

(2019) Ajitha Thanabalasuriar et al.   Cell Host & Microbe

Treatment Efficacy of MEDI3902 in Pseudomonas aeruginosa Bloodstream Infection and Acute Pneumonia Rabbit Models

(2019) Hoan N. Le et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

MEDI3902 Correlates of Protection against Severe Pseudomonas aeruginosa Pneumonia in a Rabbit Acute Pneumonia Model

(2018) Hoan N. Le et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pseudomonas aeruginosa PcrV and Psl, the molecular targets of bispecific antibody MEDI3902, are conserved among diverse global clinical isolates

(2018) D E Tabor et al.   JOURNAL OF INFECTIOUS DISEASES

Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature

(2017) Ajitha Thanabalasuriar et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-6 Family Cytokines

(2017) Stefan Rose-John   Cold Spring Harbor Perspectives in Biology

Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis

(2016) Lonneke A. van Vught et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Osteopontin is increased in cystic fibrosis and can skew the functional balance between ELR-positive and ELR-negative CXC-chemokines

(2015) Sandra Jovic et al.   Journal of Cystic Fibrosis

Cytosolic phospholipase A2α enhances mouse mortality induced by Pseudomonas aeruginosa pulmonary infection via interleukin 6

(2014) Laurent Guillemot et al.   BIOCHIMIE

Mechanisms of Oncostatin M-Induced Pulmonary Inflammation and Fibrosis

(2014) A. Mozaffarian et al.   JOURNAL OF IMMUNOLOGY

A multifunctional bispecific antibody protects against Pseudomonas aeruginosa

(2014) A. DiGiandomenico et al.   Science Translational Medicine

Assessment of an Anti-Alpha-Toxin Monoclonal Antibody for Prevention and Treatment of Staphylococcus aureus-Induced Pneumonia

(2013) L. Hua et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Type III Secretion of ExoU Is Critical during Early Pseudomonas aeruginosa Pneumonia

(2013) H. A. Howell et al.   mBio

Identification of broadly protective human antibodies toPseudomonas aeruginosaexopolysaccharide Psl by phenotypic screening

(2012) Antonio DiGiandomenico et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Leukemia Inhibitory Factor Signaling Is Required for Lung Protection during Pneumonia

(2012) L. J. Quinton et al.   JOURNAL OF IMMUNOLOGY

An Official American Thoracic Society Workshop Report: Features and Measurements of Experimental Acute Lung Injury in Animals

(2011) Gustavo Matute-Bello et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Interleukin-23-Mediated Inflammation in Pseudomonas aeruginosa Pulmonary Infection

(2011) Patricia J. Dubin et al.   INFECTION AND IMMUNITY

Microbial Etiologies of Hospital‐Acquired Bacterial Pneumonia and Ventilator‐Associated Bacterial Pneumonia

(2010) Ronald N. Jones   CLINICAL INFECTIOUS DISEASES

Development of animal models for the acute respiratory distress syndrome

(2009) J. A. Bastarache et al.   Disease Models & Mechanisms

Animal models of acute lung injury

(2008) Gustavo Matute-Bello et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Depletion of phagocytes in the reticuloendothelial system causes increased inflammation and mortality in rabbits with Pseudomonas aeruginosa pneumonia

(2008) Kiyoyasu Kurahashi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The role of chemokines in neutrophil biology

(2007) Yoshiro Kobayashi   Frontiers in Bioscience-Landmark