Augmentation of histone deacetylase 3 (HDAC3) epigenetic signature at the interface of proinflammation and insulin resistance in patients with type 2 diabetes

Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats

(2015) M. Lundh et al.   DIABETES OBESITY & METABOLISM

Altered immunometabolism at the interface of increased endoplasmic reticulum (ER) stress in patients with type 2 diabetes

(2015) R. Lenin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Conditional deletion of Hdac3 in osteoprogenitor cells attenuates diet-induced systemic metabolic dysfunction

(2015) Meghan E. McGee-Lawrence et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Exercise increases the binding of MEF2A to the Cpt1b promoter in mouse skeletal muscle

(2014) H. Yuan et al.   Acta Physiologica

Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: Study in juvenile diabetic rat

(2014) S. Khan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Insights Into the Role of the Microbiome in Obesity and Type 2 Diabetes

(2014) Annick V. Hartstra et al.   DIABETES CARE

Role of epigenetic mechanisms in the development of chronic complications of diabetes

(2014) Malgorzata Wegner et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions

(2014) M. A. Hoeksema et al.   EMBO Molecular Medicine

Deleted in Breast Cancer 1 (DBC1) Protein Regulates Hepatic Gluconeogenesis

(2014) Veronica Nin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of HDAC3 as a strategy for developing novel diabetes therapeutics

(2014) Bennett C Meier et al.   Epigenomics

Histone deacetylases as targets for treatment of multiple diseases

(2013) Jinhua Tang et al.   CLINICAL SCIENCE

Improving Insulin Sensitivity With HDAC Inhibitor

(2013) J. Ye   DIABETES

Diabetes in South Asians: Is the Phenotype Different?

(2013) R. Unnikrishnan et al.   DIABETES

Association between low SIRT1 expression in visceral and subcutaneous adipose tissues and metabolic abnormalities in women with obesity and type 2 diabetes

(2013) Young Sook Song et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Three single nucleotide variants of the HDAC gene are associated with type 2 diabetes mellitus in a Chinese population: A community-based case–control study

(2013) Zhuanping Zeng et al.   GENE

Effects of short chain fatty acid producing bacteria on epigenetic regulation of FFAR3 in type 2 diabetes and obesity

(2013) Marlene Remely et al.   GENE

Histone deacetylase isoforms regulate innate immune responses by deacetylating mitogen-activated protein kinase phosphatase-1

(2013) Y. Jeong et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes

(2013) J.H. Wang et al.   OSTEOARTHRITIS AND CARTILAGE

Effects of Sodium Butyrate and Its Synthetic Amide Derivative on Liver Inflammation and Glucose Tolerance in an Animal Model of Steatosis Induced by High Fat Diet

(2013) Giuseppina Mattace Raso et al.   PLoS One

High-Fat Diet Reduces the Formation of Butyrate, but Increases Succinate, Inflammation, Liver Fat and Cholesterol in Rats, while Dietary Fibre Counteracts These Effects

(2013) Greta Jakobsdottir et al.   PLoS One

Rapid changes in histone deacetylases and inflammatory gene expression in expert meditators

(2013) Perla Kaliman et al.   PSYCHONEUROENDOCRINOLOGY

Sirtuin-1 is a nutrient-dependent modulator of inflammation

(2013) Maya E. Kotas et al.   Adipocyte

Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

(2012) A. Galmozzi et al.   DIABETES

Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

(2012) M. Lundh et al.   DIABETOLOGIA

Histone Deacetylase 3 Mediates Allergic Skin Inflammation by Regulating Expression of MCP1 Protein

(2012) Youngmi Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

SirT1 Regulates Adipose Tissue Inflammation

(2011) M. P. Gillum et al.   DIABETES

High-sensitivity C-reactive protein: a novel cardiovascular risk predictor in type 2 diabetics with normal lipid profile

(2011) Shilpa B. Asegaonkar et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes

(2011) M. Balasubramanyam et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

High expression of liver histone deacetylase 3 contributes to high-fat-diet-induced metabolic syndrome by suppressing the PPAR-γ and LXR-α-pathways in E3 rats

(2011) Dongmin Li et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Downregulation of the Longevity-Associated Protein Sirtuin 1 in Insulin Resistance and Metabolic Syndrome: Potential Biochemical Mechanisms

(2010) S. V. de Kreutzenberg et al.   DIABETES

HDAC3 Is Negatively Regulated by the Nuclear Protein DBC1

(2010) Claudia C. S. Chini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Statins Control Oxidized LDL-Mediated Histone Modifications and Gene Expression in Cultured Human Endothelial Cells

(2009) Philippe Dje N'Guessan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes

(2009) Charlotte Ling et al.   DIABETES

Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon

(2008) Markus Waldecker et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

(2008) T. Yoshizaki et al.   MOLECULAR AND CELLULAR BIOLOGY