Synthesis of Hybrid Cyclopeptides through Enzymatic Macrocyclization

Enzymatic Macrocyclization of 1,2,3-Triazole Peptide Mimetics

(2016) Emilia Oueis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Derivatisable Cyanobactin Analogues: A Semisynthetic Approach

(2015) Emilia Oueis et al.   CHEMBIOCHEM

Modularity of RiPP Enzymes Enables Designed Synthesis of Decorated Peptides

(2015) Debosmita Sardar et al.   CHEMISTRY & BIOLOGY

Structural analysis of leader peptide binding enables leader-free cyanobactin processing

(2015) Jesko Koehnke et al.   Nature Chemical Biology

The re-emergence of natural products for drug discovery in the genomics era

(2015) Alan L. Harvey et al.   NATURE REVIEWS DRUG DISCOVERY

Macrocycles: lessons from the distant past, recent developments, and future directions

(2015) Andrei K. Yudin   Chemical Science

An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides

(2014) Wael E. Houssen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The origins of cyanobactin chemistry and biology

(2014) Marcel Jaspars   CHEMICAL COMMUNICATIONS

The structural biology of patellamide biosynthesis

(2014) Jesko Koehnke et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Form and Function in Cyclic Peptide Natural Products: A Pharmacokinetic Perspective

(2013) Andrew T. Bockus et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Macrocyclic Drugs and Synthetic Methodologies toward Macrocycles

(2013) Xufen Yu et al.   MOLECULES

Cyclic Peptides as Therapeutic Agents and Biochemical Tools

(2012) Sang-Hoon Joo   Biomolecules & Therapeutics

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Synthesis of N-methylated cyclic peptides

(2012) Jayanta Chatterjee et al.   Nature Protocols

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain

(2012) Jesko Koehnke et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of natural product diversity in chemical biology

(2011) Jiyong Hong   CURRENT OPINION IN CHEMICAL BIOLOGY

On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds

(2011) Tina R White et al.   Nature Chemical Biology

Biologically active secondary metabolites from marine cyanobacteria

(2010) Joshawna K Nunnery et al.   CURRENT OPINION IN BIOTECHNOLOGY

Modern Natural Products Drug Discovery and Its Relevance to Biodiversity Conservation

(2010) David G. I. Kingston   JOURNAL OF NATURAL PRODUCTS

Circular Logic: Nonribosomal Peptide-like Macrocyclization with a Ribosomal Peptide Catalyst

(2010) John A. McIntosh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

d-Cysteine occurrence in thiostrepton may not necessitate an epimerase

(2009) Sebastian Schoof et al.   CHEMICAL COMMUNICATIONS

Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?

(2009) Hong-Fang Ji et al.   EMBO REPORTS

The exploration of macrocycles for drug discovery — an underexploited structural class

(2008) Edward M. Driggers et al.   NATURE REVIEWS DRUG DISCOVERY