Impact of Dendrimer Terminal Group Chemistry on Blockage of the Anthrax Toxin Channel: A Single Molecule Study

pH controlled gating of toxic protein pores by dendrimers

(2016) Taraknath Mandal et al.   Nanoscale

Chloroquine Analog Interaction with C2- and Iota-Toxin in Vitro and in Living Cells

(2016) Angelika Kronhardt et al.   Toxins

Dendrimers in Medicine: Therapeutic Concepts and Pharmaceutical Challenges

(2015) Lin-ping Wu et al.   BIOCONJUGATE CHEMISTRY

Conductance hysteresis in the voltage-dependent anion channel

(2015) Shay M. Rappaport et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Dendrimers in Nanoscale Confinement: The Interplay between Conformational Change and Nanopore Entrance

(2015) Emel Ficici et al.   NANO LETTERS

Atomic structure of anthrax protective antigen pore elucidates toxin translocation

(2015) Jiansen Jiang et al.   NATURE

Cationic PAMAM Dendrimers as Pore-Blocking Binary Toxin Inhibitors

(2014) Philip Förstner et al.   BIOMACROMOLECULES

Alpha-Synuclein Lipid-Dependent Membrane Binding and Translocation through the α-Hemolysin Channel

(2014) Philip A. Gurnev et al.   BIOPHYSICAL JOURNAL

Review: A History of Cyclodextrins

(2014) Grégorio Crini   CHEMICAL REVIEWS

Designing inhibitors of anthrax toxin

(2014) Ekaterina M Nestorovich et al.   Expert Opinion on Drug Discovery

Acidification Asymmetrically Affects Voltage-dependent Anion Channel Implicating the Involvement of Salt Bridges

(2014) Oscar Teijido et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deswelling and Electrolyte Dissipation in Free Diffusion of Charged PAMAM Dendrimers

(2014) Emilio Garcia-Fernandez et al.   Journal of Physical Chemistry Letters

Tailored Cyclodextrin Pore Blocker Protects Mammalian Cells from Clostridium difficile Binary Toxin CDT

(2014) Maurice Roeder et al.   Toxins

Anthrax toxin-induced rupture of artificial lipid bilayer membranes

(2013) Brian J. Nablo et al.   JOURNAL OF CHEMICAL PHYSICS

Single-molecule interrogation of a bacterial sugar transporter allows the discovery of an extracellular inhibitor

(2013) Lingbing Kong et al.   Nature Chemistry

Designed Azolopyridinium Salts Block Protective Antigen Pores In Vitro and Protect Cells from Anthrax Toxin

(2013) Christoph Beitzinger et al.   PLoS One

Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin

(2013) Laurence Abrami et al.   Cell Reports

Interactions of High-Affinity Cationic Blockers with the Translocation Pores of B. anthracis, C. botulinum, and C. perfringens Binary Toxins

(2012) Sergey M. Bezrukov et al.   BIOPHYSICAL JOURNAL

Probing Tubulin-Blocked State of VDAC by Varying Membrane Surface Charge

(2012) Philip A. Gurnev et al.   BIOPHYSICAL JOURNAL

Obstructing Toxin Pathways by Targeted Pore Blockage

(2012) Ekaterina M. Nestorovich et al.   CHEMICAL REVIEWS

Membrane Lipid Composition Regulates Tubulin Interaction with Mitochondrial Voltage-dependent Anion Channel

(2012) Tatiana K. Rostovtseva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structured water in polyelectrolyte dendrimers: Understanding small angle neutron scattering results through atomistic simulation

(2012) Bin Wu et al.   JOURNAL OF CHEMICAL PHYSICS

Anthrax Lethal Factor Cleavage of Nlrp1 Is Required for Activation of the Inflammasome

(2012) Jonathan L. Levinsohn et al.   PLoS Pathogens

Nanoparticle Size and Surface Charge Determine Effects of PAMAM Dendrimers on Human Platelets in Vitro

(2011) Marina A. Dobrovolskaia et al.   MOLECULAR PHARMACEUTICS

Tailored ß-Cyclodextrin Blocks the Translocation Pores of Binary Exotoxins from C. Botulinum and C. Perfringens and Protects Cells from Intoxication

(2011) Ekaterina M. Nestorovich et al.   PLoS One

A Receptor-based Switch that Regulates Anthrax Toxin Pore Formation

(2011) Rosemarie M. Pilpa et al.   PLoS Pathogens

Counterion Condensation and Effective Charge of PAMAM Dendrimers

(2011) Ute Böhme et al.   Polymers

Blockage of Anthrax PA63 Pore by a Multicharged High-Affinity Toxin Inhibitor

(2010) Ekaterina M. Nestorovich et al.   BIOPHYSICAL JOURNAL

Effect of counterion valence on the pH responsiveness of polyamidoamine dendrimer structure

(2010) Yun Liu et al.   JOURNAL OF CHEMICAL PHYSICS

Conformations of high-generation dendritic polyelectrolytes

(2010) Sebastian Huißmann et al.   JOURNAL OF MATERIALS CHEMISTRY

The effects of pH, salt and bond stiffness on charged dendrimers

(2010) Sebastian Huißmann et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Anthrax Toxin Receptor Drives Protective Antigen Oligomerization and Stabilizes the Heptameric and Octameric Oligomer by a Similar Mechanism

(2010) Alexander F. Kintzer et al.   PLoS One

Diffusion of flexible, charged, nanoscopic molecules in solution: Size and pH dependence for PAMAM dendrimer

(2009) Prabal K. Maiti et al.   JOURNAL OF CHEMICAL PHYSICS

The Protective Antigen Component of Anthrax Toxin Forms Functional Octameric Complexes

(2009) Alexander F. Kintzer et al.   JOURNAL OF MOLECULAR BIOLOGY

PAMAM Dendrimers Undergo pH Responsive Conformational Changes without Swelling

(2009) Yi Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vivo Efficacy of  -Cyclodextrin Derivatives against Anthrax Lethal Toxin

(2008) M. Moayeri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Preventing Voltage-dependent Gating of Anthrax Toxin Channels Using Engineered Disulfides

(2008) Damon S. Anderson et al.   JOURNAL OF GENERAL PHYSIOLOGY

Structural Investigation of PAMAM Dendrimers in Aqueous Solutions Using Small-Angle Neutron Scattering: Effect of Generation

(2008) Lionel Porcar et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Counterion Distribution and ζ-Potential in PAMAM Dendrimer

(2008) Prabal K. Maiti et al.   MACROMOLECULES