The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation

The PGE2EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice

(2016) Ryan P. Ceddia et al.   ENDOCRINOLOGY

The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation

(2016) Xiaowei Wang et al.   INFECTION AND IMMUNITY

MyD88 Mediates Instructive Signaling in Dendritic Cells and Protective Inflammatory Response during Rickettsial Infection

(2016) Jeremy Bechelli et al.   INFECTION AND IMMUNITY

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo

(2016) Isabella Rauch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice

(2016) Yue Zhao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NOD1 and NOD2 signalling links ER stress with inflammation

(2016) A. Marijke Keestra-Gounder et al.   NATURE

The Pathogen-Occupied Vacuoles of Anaplasma phagocytophilum and Anaplasma marginale Interact with the Endoplasmic Reticulum

(2016) Hilary K. Truchan et al.   Frontiers in Cellular and Infection Microbiology

Type I Interferon Contributes to Noncanonical Inflammasome Activation, Mediates Immunopathology, and Impairs Protective Immunity during Fatal Infection with Lipopolysaccharide-Negative Ehrlichiae

(2015) Qin Yang et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular Pathogenesis ofEhrlichia chaffeensisInfection

(2015) Yasuko Rikihisa   Annual Review of Microbiology

Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors

(2015) Kohichi Kawahara et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Prostaglandin E2Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages

(2015) Milena Sokolowska et al.   JOURNAL OF IMMUNOLOGY

Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization

(2015) L. Zhang et al.   SCIENCE

Structural and biochemical basis for induced self-propagation of NLRC4

(2015) Z. Hu et al.   SCIENCE

Cryoelectron Tomography of the NAIP5/NLRC4 Inflammasome: Implications for NLR Activation

(2015) Christoph A. Diebolder et al.   STRUCTURE

The Tick Salivary Protein Sialostatin L2 Inhibits Caspase-1-Mediated Inflammation during Anaplasma phagocytophilum Infection

(2014) G. Chen et al.   INFECTION AND IMMUNITY

Prostaglandin E2-EP3 Signaling Induces Inflammatory Swelling by Mast Cell Activation

(2013) K. Morimoto et al.   JOURNAL OF IMMUNOLOGY

Role of the lipoxygenase pathway in RSV-induced alternatively activated macrophages leading to resolution of lung pathology

(2013) K A Shirey et al.   Mucosal Immunology

TLR2 and Nod2 Mediate Resistance or Susceptibility to Fatal Intracellular Ehrlichia Infection in Murine Models of Ehrlichiosis

(2013) Partho Chattoraj et al.   PLoS One

Reprogramming of Murine Macrophages through TLR2 Confers Viral Resistance via TRAF3-Mediated, Enhanced Interferon Production

(2013) Darren J. Perkins et al.   PLoS Pathogens

Receptor interacting protein-2 contributes to host defense againstAnaplasma phagocytophiluminfection

(2012) Bindu Sukumaran et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Anaplasma phagocytophilum: deceptively simple or simply deceptive?

(2012) Maiara S Severo et al.   Future Microbiology

ASC-dependent RIP2 Kinase Regulates Reduced PGE2 Production in Chronic Periodontitis

(2012) D.J. Taxman et al.   JOURNAL OF DENTAL RESEARCH

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

(2012) Jakob von Moltke et al.   NATURE

The biological basis of severe outcomes inAnaplasma phagocytophiluminfection

(2011) J. Stephen Dumler   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Engineering and Preclinical Evaluation of Attenuated Nontyphoidal Salmonella Strains Serving as Live Oral Vaccines and as Reagent Strains

(2011) Sharon M. Tennant et al.   INFECTION AND IMMUNITY

Subversion of host cell signaling by Orientia tsutsugamushi

(2011) Yan Ge et al.   MICROBES AND INFECTION

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

(2011) Eric M. Kofoed et al.   NATURE

Microreview: Type IV secretion in the obligatory intracellular bacterium Anaplasma phagocytophilum

(2010) Yasuko Rikihisa et al.   CELLULAR MICROBIOLOGY

Orientia tsutsugamushi induced endothelial cell activation via the NOD1-IL-32 pathway

(2010) Kyung-Ah Cho et al.   MICROBIAL PATHOGENESIS

Anaplasma phagocytophilum and Ehrlichia chaffeensis: subversive manipulators of host cells

(2010) Yasuko Rikihisa   NATURE REVIEWS MICROBIOLOGY

MyD88-Dependent Signaling Contributes to Host Defense against Ehrlichial Infection

(2010) Young-Sang Koh et al.   PLoS One

How the Noninflammasome NLRs Function in the Innate Immune System

(2010) J. P. Y. Ting et al.   SCIENCE

The Absence of Toll-Like Receptor 4 Signaling in C3H/HeJ Mice Predisposes Them to Overwhelming Rickettsial Infection and Decreased Protective Th1 Responses

(2008) J. M. Jordan et al.   INFECTION AND IMMUNITY

Prostaglandin E2Attenuates Preoptic Expression of GABAAReceptors via EP3 Receptors

(2008) Hiroyoshi Tsuchiya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rickettsiae Stimulate Dendritic Cells through Toll‐Like Receptor 4, Leading to Enhanced NK Cell Activation In Vivo

(2008) Jeffrey M. Jordan et al.   JOURNAL OF INFECTIOUS DISEASES

Emerging and re-emerging rickettsioses: endothelial cell infection and early disease events

(2008) David H. Walker et al.   NATURE REVIEWS MICROBIOLOGY