Structural and biochemical basis for induced self-propagation of NLRC4
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Structural and biochemical basis for induced self-propagation of NLRC4
Authors
Keywords
-
Journal
SCIENCE
Volume 350, Issue 6259, Pages 399-404
Publisher
American Association for the Advancement of Science (AAAS)
Online
2015-10-09
DOI
10.1126/science.aac5489
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Structural Biology of Innate Immunity
- (2015) Qian Yin et al. Annual Review of Immunology
- The NAIP/NLRC4 inflammasomes
- (2015) Russell E Vance CURRENT OPINION IN IMMUNOLOGY
- Structure of the apoptosome: mechanistic insights into activation of an initiator caspase fromDrosophila
- (2015) Yuxuan Pang et al. GENES & DEVELOPMENT
- Semi-automated selection of cryo-EM particles in RELION-1.3
- (2015) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization
- (2015) L. Zhang et al. SCIENCE
- Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation
- (2014) Xin Cai et al. CELL
- Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
- (2014) Alvin Lu et al. CELL
- An inherited mutation inNLRC4causes autoinflammation in human and mice
- (2014) Akiko Kitamura et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes
- (2014) Jeannette L. Tenthorey et al. MOLECULAR CELL
- Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation
- (2014) Neil Romberg et al. NATURE GENETICS
- An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome
- (2014) Scott W Canna et al. NATURE GENETICS
- Prion-like polymerization as a signaling mechanism
- (2014) Xin Cai et al. TRENDS IN IMMUNOLOGY
- Changes in Apaf-1 Conformation That Drive Apoptosome Assembly
- (2013) Shujun Yuan et al. BIOCHEMISTRY
- Structures of pattern recognition receptors reveal molecular mechanisms of autoinhibition, ligand recognition and oligomerization
- (2013) Watchalee Chuenchor et al. CURRENT OPINION IN IMMUNOLOGY
- Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM
- (2013) Xueming Li et al. NATURE METHODS
- Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation
- (2013) J. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal Structure of NLRC4 Reveals Its Autoinhibition Mechanism
- (2013) Z. Hu et al. SCIENCE
- Validation of Cryo-EM Structure of IP3R1 Channel
- (2013) Stephen C. Murray et al. STRUCTURE
- High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy
- (2013) Shaoxia Chen et al. ULTRAMICROSCOPY
- Inflammasomes and Their Roles in Health and Disease
- (2012) Mohamed Lamkanfi et al. Annual Review of Cell and Developmental Biology
- Recognition of Bacteria by Inflammasomes
- (2012) Jakob von Moltke et al. Annual Review of Immunology
- Formation and Structure of a NAIP5-NLRC4 Inflammasome Induced by Direct Interactions with Conserved N- and C-terminal Regions of Flagellin
- (2012) Els F. Halff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
- (2012) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- Inflammasomes in health and disease
- (2012) Till Strowig et al. NATURE
- A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?
- (2012) Haitao Wen et al. NATURE IMMUNOLOGY
- Regulation of inflammasome signaling
- (2012) Vijay A K Rathinam et al. NATURE IMMUNOLOGY
- Sensing and reacting to microbes through the inflammasomes
- (2012) Luigi Franchi et al. NATURE IMMUNOLOGY
- Prevention of overfitting in cryo-EM structure determination
- (2012) Sjors H W Scheres et al. NATURE METHODS
- The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
- (2011) Beckley K. Davis et al. Annual Review of Immunology
- Tilt-Pair Analysis of Images from a Range of Different Specimens in Single-Particle Electron Cryomicroscopy
- (2011) Richard Henderson et al. JOURNAL OF MOLECULAR BIOLOGY
- A Bayesian View on Cryo-EM Structure Determination
- (2011) Sjors H.W. Scheres JOURNAL OF MOLECULAR BIOLOGY
- The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
- (2011) Yue Zhao et al. NATURE
- Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
- (2011) Eric M. Kofoed et al. NATURE
- Crystal Structure of Full-Length Apaf-1: How the Death Signal Is Relayed in the Mitochondrial Pathway of Apoptosis
- (2011) Thomas Frank Reubold et al. STRUCTURE
- Structure of the Drosophila Apoptosome at 6.9 Å Resolution
- (2011) Shujun Yuan et al. STRUCTURE
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Crystal Structure of the Caenorhabditis elegans Apoptosome Reveals an Octameric Assembly of CED-4
- (2010) Shiqian Qi et al. CELL
- Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
- (2010) E. A. Miao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Wheel of Life, Wheel of Death: A Mechanistic Insight into Signaling by STAND Proteins
- (2009) Olivier Danot et al. STRUCTURE
- Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin
- (2008) Karla L Lightfield et al. NATURE IMMUNOLOGY
- Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics
- (2008) Leonardo G. Trabuco et al. STRUCTURE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started