Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence

TAM Receptor Signaling in Immune Homeostasis

(2015) Carla V. Rothlin et al.   Annual Review of Immunology

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

(2015) Suzanne L. Topalian et al.   CANCER CELL

Blockade of Interferon Beta, but Not Interferon Alpha, Signaling Controls Persistent Viral Infection

(2015) Cherie T. Ng et al.   Cell Host & Microbe

New insights into type I interferon and the immunopathogenesis of persistent viral infections

(2015) Laura M Snell et al.   CURRENT OPINION IN IMMUNOLOGY

Tumor-Infiltrating Dendritic Cells in Cancer Pathogenesis

(2015) Jo Marie Tran Janco et al.   JOURNAL OF IMMUNOLOGY

Overcoming T cell exhaustion in infection and cancer

(2015) Kristen E. Pauken et al.   TRENDS IN IMMUNOLOGY

T-cell exhaustion in the tumor microenvironment

(2015) Y Jiang et al.   Cell Death & Disease

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Direct Infection of Dendritic Cells during Chronic Viral Infection Suppresses Antiviral T Cell Proliferation and Induces IL-10 Expression in CD4 T Cells

(2014) Carmen Baca Jones et al.   PLoS One

Loss of the death receptor CD95 (Fas) expression by dendritic cells protects from a chronic viral infection

(2014) V. Varanasi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering and Reversing Tumor Immune Suppression

(2013) Greg T. Motz et al.   IMMUNITY

Chronic but Not Acute Virus Infection Induces Sustained Expansion of Myeloid Suppressor Cell Numbers that Inhibit Viral-Specific T Cell Immunity

(2013) Brian A. Norris et al.   IMMUNITY

Dendritic cell dysregulation during HIV-1 infection

(2013) Elizabeth Miller et al.   IMMUNOLOGICAL REVIEWS

PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

(2013) Bernd H. Zinselmeyer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39

(2013) Ivan D Mascanfroni et al.   NATURE IMMUNOLOGY

FIDEA: a server for the functional interpretation of differential expression analysis

(2013) Daniel D’Andrea et al.   NUCLEIC ACIDS RESEARCH

Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection

(2013) E. B. Wilson et al.   SCIENCE

Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling

(2013) J. R. Teijaro et al.   SCIENCE

Inflammatory dendritic cells in mice and humans

(2013) Elodie Segura et al.   TRENDS IN IMMUNOLOGY

Monitoring cellular immune markers in HIV infection

(2013) Delphine Sauce et al.   Current Opinion in HIV and AIDS

Macrophage and T Cell Produced IL-10 Promotes Viral Chronicity

(2013) Kirsten Richter et al.   PLoS Pathogens

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Timing and Magnitude of Type I Interferon Responses by Distinct Sensors Impact CD8 T Cell Exhaustion and Chronic Viral Infection

(2012) Yaming Wang et al.   Cell Host & Microbe

Emergence of Distinct Multiarmed Immunoregulatory Antigen-Presenting Cells during Persistent Viral Infection

(2012) Elizabeth B. Wilson et al.   Cell Host & Microbe

Differential Roles for RIG-I-like Receptors and Nucleic Acid-Sensing TLR Pathways in Controlling a Chronic Viral Infection

(2012) J. M. Clingan et al.   JOURNAL OF IMMUNOLOGY

Infected CD8 - dendritic cells are the predominant source of IL-10 during establishment of persistent viral infection

(2012) C. T. Ng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Suppression of HIV by Antigen Specific T Cells Derived from Engineered Hematopoietic Stem Cells

(2012) Scott G. Kitchen et al.   PLoS Pathogens

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Opposing positive and negative regulation of T cell activity during viral persistence

(2010) Laura M Fahey et al.   CURRENT OPINION IN IMMUNOLOGY

Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung

(2010) Paul S. Redford et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Tip-DC Development during Parasitic Infection Is Regulated by IL-10 and Requires CCL2/CCR2, IFN-γ and MyD88 Signaling

(2010) Tom Bosschaerts et al.   PLoS Pathogens

Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B

(2009) Paola Fisicaro et al.   GASTROENTEROLOGY

Monocyte‐Derived Dendritic Cells from HIV Type 1–Infected Individuals Show Reduced Ability to Stimulate T Cells and Have Altered Production of Interleukin (IL)–12 and IL‐10

(2009) Sandrine Buisson et al.   JOURNAL OF INFECTIOUS DISEASES

Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest

(2009) S. F. Emonet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

iNOS-Producing Inflammatory Dendritic Cells Constitute the Major Infected Cell Type during the Chronic Leishmania major Infection Phase of C57BL/6 Resistant Mice

(2009) Carl De Trez et al.   PLoS Pathogens

Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization

(2008) Nobuhiro Nakamoto et al.   GASTROENTEROLOGY

Selective expansion of a subset of exhausted CD8 T cells by  PD-L1 blockade

(2008) S. D. Blackburn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA