Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation

New Approaches for Immunization and Therapy against Human Metapneumovirus

(2015) Sherry C. Wen et al.   Clinical and Vaccine Immunology

Generation of monoclonal antibodies specific of the postfusion conformation of the Pneumovirinae fusion (F) protein

(2015) Laura Rodríguez et al.   JOURNAL OF VIROLOGICAL METHODS

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

(2015) Hadi M Yassine et al.   NATURE MEDICINE

The Pneumovirinae fusion (F) protein: A common target for vaccines and antivirals

(2015) José A. Melero et al.   VIRUS RESEARCH

Human Metapneumovirus Is Capable of Entering Cells by Fusion with Endosomal Membranes

(2015) Reagan G. Cox et al.   PLoS Pathogens

FEM: feature-enhanced map

(2015) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Human metapneumovirus: review of an important respiratory pathogen

(2014) Swagatika Panda et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Human metapneumovirus pneumonia in patients with hematological malignancies

(2014) Cendrine Godet et al.   JOURNAL OF CLINICAL VIROLOGY

Adjuvant effect of the human metapneumovirus (HMPV) matrix protein in HMPV subunit vaccines

(2014) L. Aerts et al.   JOURNAL OF GENERAL VIROLOGY

Respiratory Syncytial Virus and Other Respiratory Viral Infections in Older Adults With Moderate to Severe Influenza-like Illness

(2014) Ann R. Falsey et al.   JOURNAL OF INFECTIOUS DISEASES

Human Metapneumovirus SH and G Glycoproteins Inhibit Macropinocytosis-Mediated Entry into Human Dendritic Cells and Reduce CD4+ T Cell Activation

(2014) C. Le Nouen et al.   JOURNAL OF VIROLOGY

Roles of the Putative Integrin-Binding Motif of the Human Metapneumovirus Fusion (F) Protein in Cell-Cell Fusion, Viral Infectivity, and Pathogenesis

(2014) Y. Wei et al.   JOURNAL OF VIROLOGY

Polyclonal and monoclonal antibodies specific for the six-helix bundle of the human respiratory syncytial virus fusion glycoprotein as probes of the protein post-fusion conformation

(2014) Concepción Palomo et al.   VIROLOGY

Activation of paramyxovirus membrane fusion and virus entry

(2014) Theodore S Jardetzky et al.   Current Opinion in Virology

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Cross-neutralization of four paramyxoviruses by a human monoclonal antibody

(2013) Davide Corti et al.   NATURE

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

(2013) J. S. McLellan et al.   SCIENCE

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

(2013) J. S. McLellan et al.   SCIENCE

Human Metapneumovirus (HMPV) Binding and Infection Are Mediated by Interactions between the HMPV Fusion Protein and Heparan Sulfate

(2012) A. Chang et al.   JOURNAL OF VIROLOGY

The Human Metapneumovirus Fusion Protein Mediates Entry via an Interaction with RGD-Binding Integrins

(2012) R. G. Cox et al.   JOURNAL OF VIROLOGY

Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site

(2012) Xiaolin Wen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Respiratory Syncytial Virus Fusion Glycoprotein Expressed in Insect Cells Form Protein Nanoparticles That Induce Protective Immunity in Cotton Rats

(2012) Gale Smith et al.   PLoS One

Neutralizing antibodies against the preactive form of respiratory syncytial virus fusion protein offer unique possibilities for clinical intervention

(2012) M. Magro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein

(2012) B. D. Welch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Human Metapneumovirus: Lessons Learned over the First Decade

(2011) V. Schildgen et al.   CLINICAL MICROBIOLOGY REVIEWS

Residues of the Human Metapneumovirus Fusion (F) Protein Critical for Its Strain-Related Fusion Phenotype: Implications for the Virus Replication Cycle

(2011) V. Mas et al.   JOURNAL OF VIROLOGY

Recombinant Sendai Viruses Expressing Fusion Proteins with Two Furin Cleavage Sites Mimic the Syncytial and Receptor-Independent Infection Properties of Respiratory Syncytial Virus

(2011) J. Rawling et al.   JOURNAL OF VIROLOGY

Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

(2011) J. S. McLellan et al.   JOURNAL OF VIROLOGY

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

(2011) K. A. Swanson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F

(2010) J. S. McLellan et al.   JOURNAL OF VIROLOGY

Soluble recombinant human metapneumovirus G protein is immunogenic but not protective

(2010) Alex B. Ryder et al.   VACCINE

Structure of the Newcastle disease virus F protein in the post-fusion conformation

(2010) Kurt Swanson et al.   VIROLOGY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Integrin  v 1 promotes infection by human metapneumovirus

(2009) G. Cseke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of antibody neutralization epitopes on the fusion protein of human metapneumovirus

(2008) N. D. Ulbrandt et al.   JOURNAL OF GENERAL VIROLOGY

Low-pH-Induced Membrane Fusion Mediated by Human Metapneumovirus F Protein Is a Rare, Strain-Dependent Phenomenon

(2008) S. Herfst et al.   JOURNAL OF VIROLOGY

Role of Cellular Glycosaminoglycans and Charged Regions of Viral G Protein in Human Metapneumovirus Infection

(2008) S. Thammawat et al.   JOURNAL OF VIROLOGY

Efficient Multiplication of Human Metapneumovirus in Vero Cells Expressing the Transmembrane Serine Protease TMPRSS2

(2008) Y. Shirogane et al.   JOURNAL OF VIROLOGY

Human Metapneumovirus Small Hydrophobic Protein Inhibits NF- B Transcriptional Activity

(2008) X. Bao et al.   JOURNAL OF VIROLOGY

Insertion of the Two Cleavage Sites of the Respiratory Syncytial Virus Fusion Protein in Sendai Virus Fusion Protein Leads to Enhanced Cell-Cell Fusion and a Decreased Dependency on the HN Attachment Protein for Activity

(2008) J. Rawling et al.   JOURNAL OF VIROLOGY

Immunogenicity and efficacy of two candidate human metapneumovirus vaccines in cynomolgus macaques

(2008) Sander Herfst et al.   VACCINE