Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility

Prions efficiently cross the intestinal barrier after oral administration: Study of the bioavailability, and cellular and tissue distribution in vivo

(2016) Akihiko Urayama et al.   Scientific Reports

Microfold Cells Actively Translocate Mycobacterium tuberculosis to Initiate Infection

(2016) Vidhya R. Nair et al.   Cell Reports

RANKL regulates differentiation of microfold cells in mouse nasopharynx-associated lymphoid tissue (NALT)

(2015) Mami Mutoh et al.   CELL AND TISSUE RESEARCH

Immediate and Ongoing Detection of Prions in the Blood of Hamsters and Deer following Oral, Nasal, or Blood Inoculations

(2015) Alan M. Elder et al.   JOURNAL OF VIROLOGY

Oral Norovirus Infection Is Blocked in Mice Lacking Peyer's Patches and Mature M Cells

(2015) Abimbola O. Kolawole et al.   JOURNAL OF VIROLOGY

The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis

(2015) David S. Donaldson et al.   JOURNAL OF VIROLOGY

The lymph nodes draining the small intestine and colon are anatomically separate and immunologically distinct

(2015) S A Houston et al.   Mucosal Immunology

Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria

(2015) D Rios et al.   Mucosal Immunology

An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells

(2015) Jonathan J. Powell et al.   Nature Nanotechnology

Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity

(2015) Takuhiro Matsumura et al.   Nature Communications

Comprehensive Gene Expression Profiling of Peyer's Patch M Cells, Villous M-Like Cells, and Intestinal Epithelial Cells

(2014) K. Terahara et al.   JOURNAL OF IMMUNOLOGY

Efficient Norovirus and Reovirus Replication in the Mouse Intestine Requires Microfold (M) Cells

(2014) M. B. Gonzalez-Hernandez et al.   JOURNAL OF VIROLOGY

Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23

(2014) D S Donaldson et al.   Mucosal Immunology

Visualization of the entire differentiation process of murine M cells: suppression of their maturation in cecal patches

(2014) S Kimura et al.   Mucosal Immunology

Variant CJD

(2014) Abigail B Diack et al.   Prion

Luminal Bacteria Recruit CD103+ Dendritic Cells into the Intestinal Epithelium to Sample Bacterial Antigens for Presentation

(2013) Julia Farache et al.   IMMUNITY

Evidence of subclinical prion disease in aged mice following exposure to bovine spongiform encephalopathy

(2013) K. L. Brown et al.   JOURNAL OF GENERAL VIROLOGY

Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium

(2013) N A Mabbott et al.   Mucosal Immunology

The functional maturation of M cells is dramatically reduced in the Peyer’s patches of aged mice

(2013) A Kobayashi et al.   Mucosal Immunology

Follicular Dendritic Cells Emerge from Ubiquitous Perivascular Precursors

(2012) Nike Julia Krautler et al.   CELL

Salmonella Transforms Follicle-Associated Epithelial Cells into M Cells to Promote Intestinal Invasion

(2012) Amin Tahoun et al.   Cell Host & Microbe

Genetic Depletion of Complement Receptors CD21/35 Prevents Terminal Prion Disease in a Mouse Model of Chronic Wasting Disease

(2012) Brady Michel et al.   JOURNAL OF IMMUNOLOGY

B Cell-Specific S1PR1 Deficiency Blocks Prion Dissemination between Secondary Lymphoid Organs

(2012) S. W. F. Mok et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Brucella abortus Exploits a Cellular Prion Protein on Intestinal M Cells as an Invasive Receptor

(2012) G. Nakato et al.   JOURNAL OF IMMUNOLOGY

Rapid Transepithelial Transport of Prions following Inhalation

(2012) A. E. Kincaid et al.   JOURNAL OF VIROLOGY

Peyer's Patch M Cells Derived from Lgr5+ Stem Cells Require SpiB and Are Induced by RankL in Cultured "Miniguts"

(2012) W. de Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcription factor Spi-B–dependent and –independent pathways for the development of Peyer’s patch M cells

(2012) S Sato et al.   Mucosal Immunology

M cell-depletion blocks oral prion disease pathogenesis

(2012) D S Donaldson et al.   Mucosal Immunology

The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells

(2012) Takashi Kanaya et al.   NATURE IMMUNOLOGY

Orally Administered Prion Protein Is Incorporated by M Cells and Spreads into Lymphoid Tissues with Macrophages in Prion Protein Knockout Mice

(2011) Ikuro Takakura et al.   AMERICAN JOURNAL OF PATHOLOGY

Peyer's Patch Dendritic Cells Sample Antigens by Extending Dendrites Through M Cell-Specific Transcellular Pores

(2011) Hugues Lelouard et al.   GASTROENTEROLOGY

Convergent and Divergent Development among M Cell Lineages in Mouse Mucosal Epithelium

(2011) Jing Wang et al.   JOURNAL OF IMMUNOLOGY

Follicular Dendritic Cell-Specific Prion Protein (PrPc) Expression Alone Is Sufficient to Sustain Prion Infection in the Spleen

(2011) Laura McCulloch et al.   PLoS Pathogens

Prion Uptake in the Gut: Identification of the First Uptake and Replication Sites

(2011) Pekka Kujala et al.   PLoS Pathogens

Characterization of the role of dendritic cells in prion transfer to primary neurons

(2010) Christelle Langevin et al.   BIOCHEMICAL JOURNAL

Transcytosis of Murine-Adapted Bovine Spongiform Encephalopathy Agents in an In Vitro Bovine M Cell Model

(2010) K. Miyazawa et al.   JOURNAL OF VIROLOGY

Generating a Prion with Bacterially Expressed Recombinant Prion Protein

(2010) F. Wang et al.   SCIENCE

RANKL Is Necessary and Sufficient to Initiate Development of Antigen-Sampling M Cells in the Intestinal Epithelium

(2009) K. A. Knoop et al.   JOURNAL OF IMMUNOLOGY

The Effects of Host Age on Follicular Dendritic Cell Status Dramatically Impair Scrapie Agent Neuroinvasion in Aged Mice

(2009) K. L. Brown et al.   JOURNAL OF IMMUNOLOGY

Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response

(2009) Koji Hase et al.   NATURE

Prions hijack tunnelling nanotubes for intercellular spread

(2009) Karine Gousset et al.   NATURE CELL BIOLOGY

Resistance of Chemokine Receptor 6-Deficient Mice to Yersinia Enterocolitica Infection

(2008) Sabine Westphal et al.   AMERICAN JOURNAL OF PATHOLOGY

Lymphotoxin-Dependent Prion Replication in Inflammatory Stromal Cells of Granulomas

(2008) Mathias Heikenwalder et al.   IMMUNITY

Bacterial Colitis Increases Susceptibility to Oral Prion Disease

(2008) Christina J. Sigurdson et al.   JOURNAL OF INFECTIOUS DISEASES