An Oncogenic Virus Promotes Cell Survival and Cellular Transformation by Suppressing Glycolysis

18F-fluorodeoxyglucose Positron Emission Tomography in Kaposi Sarcoma Herpesvirus–Associated Multicentric Castleman Disease: Correlation With Activity, Severity, Inflammatory and Virologic Parameters

(2015) Mark N. Polizzotto et al.   JOURNAL OF INFECTIOUS DISEASES

Kaposi Sarcoma–Associated Herpesvirus-Associated Malignancies: Epidemiology, Pathogenesis, and Advances in Treatment

(2015) Manisha Bhutani et al.   SEMINARS IN ONCOLOGY

Viral Cyclin promotes KSHV-induced cellular transformation and tumorigenesis by overriding contact inhibition

(2014) Tiffany Jones et al.   CELL CYCLE

Metabolism of stromal and immune cells in health and disease

(2014) Bart Ghesquière et al.   NATURE

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides

(2014) Kıvanç Birsoy et al.   NATURE

HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway

(2014) Min Xue et al.   NUCLEIC ACIDS RESEARCH

Glutamate Secretion and Metabotropic Glutamate Receptor 1 Expression during Kaposi's Sarcoma-Associated Herpesvirus Infection Promotes Cell Proliferation

(2014) Mohanan Valiya Veettil et al.   PLoS Pathogens

Kaposi's Sarcoma Herpesvirus MicroRNAs Induce Metabolic Transformation of Infected Cells

(2014) Ohad Yogev et al.   PLoS Pathogens

Control of Nutrient Stress-Induced Metabolic Reprogramming by PKCζ in Tumorigenesis

(2013) Li Ma et al.   CELL

Kaposi sarcoma associated herpesvirus (KSHV) induces AKT hyperphosphorylation, bortezomib-resistance and GLUT-1 plasma membrane exposure in THP-1 monocytic cell line

(2013) Roberta Gonnella et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

HIV-1 Tat Promotes Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) vIL-6-Induced Angiogenesis and Tumorigenesis by Regulating PI3K/PTEN/AKT/GSK-3β Signaling Pathway

(2013) Feng Zhou et al.   PLoS One

KSHV MicroRNAs Mediate Cellular Transformation and Tumorigenesis by Redundantly Targeting Cell Growth and Survival Pathways

(2013) Rosalie Moody et al.   PLoS Pathogens

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Pyruvate Kinase M2: Multiple Faces for Conferring Benefits on Cancer Cells

(2012) M. Tamada et al.   CLINICAL CANCER RESEARCH

Targeting the hallmarks of cancer

(2012) Pierre Hainaut et al.   CURRENT OPINION IN ONCOLOGY

Direct and efficient cellular transformation of primary rat mesenchymal precursor cells by KSHV

(2012) Tiffany Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

Coupling of Glucose Deprivation with Impaired Histone H2B Monoubiquitination in Tumors

(2012) Yasuyo Urasaki et al.   PLoS One

Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma

(2012) A. P. Bhatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer

(2012) Barbara Chaneton et al.   TRENDS IN BIOCHEMICAL SCIENCES

Global Metabolic Profiling of Infection by an Oncogenic Virus: KSHV Induces and Requires Lipogenesis for Survival of Latent Infection

(2012) Tracie Delgado et al.   PLoS Pathogens

Selective growth inhibition by glycogen synthase kinase-3 inhibitors in tumorigenic HeLa hybrid cells is mediated through NF-κB-dependent GLUT3 expression

(2012) M Watanabe et al.   Oncogenesis

FDG PET/CT in Patients With HIV

(2011) Jessica M. Davison et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

(2011) Stephanos Pavlides et al.   CELL CYCLE

Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect

(2011) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration

(2011) Claudio Mauro et al.   NATURE CELL BIOLOGY

Imaging of HIV-Associated Kaposi Sarcoma; F-18-FDG-PET/CT and In-111-Bevacizumabscintigraphy

(2010) Addy van de Luijtgaarden et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA

(2010) Xiufen Lei et al.   NATURE CELL BIOLOGY

Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells

(2010) T. Delgado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry

(2009) A. Hirayama et al.   CANCER RESEARCH

Akt and c-Myc Differentially Activate Cellular Metabolic Programs and Prime Cells to Bioenergetic Inhibition

(2009) Yongjun Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

[18F]Fluorodeoxyglucose Positron Emission Tomography Correlates With Akt Pathway Activity but Is Not Predictive of Clinical Outcome During mTOR Inhibitor Therapy

(2009) Wen Wee Ma et al.   JOURNAL OF CLINICAL ONCOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The tumor microenvironment and metastatic disease

(2008) Sarah Jane Lunt et al.   CLINICAL & EXPERIMENTAL METASTASIS

Activation of Akt through gp130 Receptor Signaling Is Required for Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphatic Reprogramming of Endothelial Cells

(2008) V. A. Morris et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus Latent Gene vFLIP Inhibits Viral Lytic Replication through NF- B-Mediated Suppression of the AP-1 Pathway: a Novel Mechanism of Virus Control of Latency

(2008) F.-C. Ye et al.   JOURNAL OF VIROLOGY

Pyruvate kinase M2 is a phosphotyrosine-binding protein

(2008) Heather R. Christofk et al.   NATURE

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE

p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation

(2008) Keiko Kawauchi et al.   NATURE CELL BIOLOGY

Genetic disruption of KSHV major latent nuclear antigen LANA enhances viral lytic transcriptional program

(2008) Qiuhua Li et al.   VIROLOGY