Two Different Virulence-Related Regulatory Pathways in Borrelia burgdorferi Are Directly Affected by Osmotic Fluxes in the Blood Meal of Feeding Ixodes Ticks

Interaction of the Lyme disease spirochete with its tick vector

(2016) Melissa J. Caimano et al.   CELLULAR MICROBIOLOGY

Spirochetal motility and chemotaxis in the natural enzootic cycle and development of Lyme disease

(2015) MD A. Motaleb et al.   CURRENT OPINION IN MICROBIOLOGY

Cyclic di-GMP Modulates Gene Expression in Lyme Disease Spirochetes at the Tick-Mammal Interface To Promote Spirochete Survival during the Blood Meal and Tick-to-Mammal Transmission

(2015) Melissa J. Caimano et al.   INFECTION AND IMMUNITY

The EMBL-EBI bioinformatics web and programmatic tools framework

(2015) Weizhong Li et al.   NUCLEIC ACIDS RESEARCH

The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation

(2015) Dan Drecktrah et al.   PLoS Pathogens

Stage-specific global alterations in the transcriptomes of Lyme disease spirochetes during tick feeding and following mammalian host adaptation

(2014) Radha Iyer et al.   MOLECULAR MICROBIOLOGY

Global Repression of Host-Associated Genes of the Lyme Disease Spirochete through Post-Transcriptional Modulation of the Alternative Sigma Factor RpoS

(2014) Daniel P. Dulebohn et al.   PLoS One

Borreliahost adaptation Regulator (BadR) regulatesrpoSto modulate host adaptation and virulence factors inBorrelia burgdorferi

(2013) Christine L. Miller et al.   MOLECULAR MICROBIOLOGY

Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity

(2012) Tao Lin et al.   PLoS One

The Hybrid Histidine Kinase Hk1 Is Part of a Two-Component System That Is Essential for Survival of Borrelia burgdorferi in Feeding Ixodes scapularis Ticks

(2011) Melissa J. Caimano et al.   INFECTION AND IMMUNITY

The diguanylate cyclase, Rrp1, regulates critical steps in the enzootic cycle of the Lyme disease spirochetes

(2011) Jessica L. Kostick et al.   MOLECULAR MICROBIOLOGY

Cyclic di-GMP is Essential for the Survival of the Lyme Disease Spirochete in Ticks

(2011) Ming He et al.   PLoS Pathogens

Gene Regulation inBorrelia burgdorferi

(2010) D. Scott Samuels   Annual Review of Microbiology

Bacterial Osmoregulation: A Paradigm for the Study of Cellular Homeostasis

(2010) Janet M. Wood   Annual Review of Microbiology

Rrp2, a  54-Dependent Transcriptional Activator of Borrelia burgdorferi, Activates rpoS in an Enhancer-Independent Manner

(2009) J. S. Blevins et al.   JOURNAL OF BACTERIOLOGY

Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks

(2009) Star M. Dunham-Ems et al.   JOURNAL OF CLINICAL INVESTIGATION

Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator ofBorrelia burgdorfericore cellular functions

(2009) Elizabeth A. Rogers et al.   MOLECULAR MICROBIOLOGY