Secretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 Receptors

Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy

(2014) Norihiko Yokoi et al.   NATURE MEDICINE

Low penetrance of autosomal dominant lateral temporal epilepsy in Italian families withoutLGI1mutations

(2013) Roberto Michelucci et al.   EPILEPSIA

Autoantibodies to Epilepsy-Related LGI1 in Limbic Encephalitis Neutralize LGI1-ADAM22 Interaction and Reduce Synaptic AMPA Receptors

(2013) T. Ohkawa et al.   JOURNAL OF NEUROSCIENCE

A newly discovered LGI1 mutation in Korean family with autosomal dominant lateral temporal lobe epilepsy

(2013) Moon Kyu Lee et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Bluues server: electrostatic properties of wild-type and mutated protein structures

(2012) I. Walsh et al.   BIOINFORMATICS

Domain-dependent clustering and genotype-phenotype analysis of LGI1 mutations in ADPEAF

(2012) Y.-Y. Ho et al.   NEUROLOGY

Low penetrance and effect on protein secretion of LGI1 mutations causing autosomal dominant lateral temporal epilepsy

(2011) Carlo Di Bonaventura et al.   EPILEPSIA

Familial temporal lobe epilepsy with psychic auras associated with a novel LGI1 mutation

(2011) P. Striano et al.   NEUROLOGY

A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins

(2011) Emanuela Leonardi et al.   PLoS One

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia

(2010) Sarosh R. Irani et al.   BRAIN

Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series

(2010) Meizan Lai et al.   LANCET NEUROLOGY

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

OMA 2011: orthology inference among 1000 complete genomes

(2010) A. M. Altenhoff et al.   NUCLEIC ACIDS RESEARCH

Disruption of LGI1–linked synaptic complex causes abnormal synaptic transmission and epilepsy

(2010) Yuko Fukata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lateral temporal lobe epilepsies: Clinical and genetic features

(2009) Roberto Michelucci et al.   EPILEPSIA

Mutations inLGI1gene in Japanese families with autosomal dominant lateral temporal lobe epilepsy: The first report from Asian families

(2009) Jun Kawamata et al.   EPILEPSIA

Distribution of the epilepsy-related Lgi1 protein in rat cortical neurons

(2009) Manuela Malatesta et al.   HISTOCHEMISTRY AND CELL BIOLOGY

LGI1mutations in autosomal dominant and sporadic lateral temporal epilepsy

(2009) Carlo Nobile et al.   HUMAN MUTATION

Structural Characterization of the Ectodomain of a Disintegrin and Metalloproteinase-22 (ADAM22), a Neural Adhesion Receptor Instead of Metalloproteinase

(2009) Heli Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LGI1-associated epilepsy through altered ADAM23-dependent neuronal morphology

(2009) Katherine Owuor et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A Novel Loss-of-Function LGI1 Mutation Linked to Autosomal Dominant Lateral Temporal Epilepsy

(2008) Pasquale Striano et al.   ARCHIVES OF NEUROLOGY

Autosomal dominant lateral temporal epilepsy: Absence of mutations in ADAM22 and Kv1 channel genes encoding LGI1-associated proteins

(2008) Erica Diani et al.   EPILEPSY RESEARCH

Penetrance of LGI1 mutations in autosomal dominant partial epilepsy with auditory features

(2008) M. J. Rosanoff et al.   NEUROLOGY