miR-190 Enhances HIF-Dependent Responses to Hypoxia in Drosophila by Inhibiting the Prolyl-4-hydroxylase Fatiga

MiR-190b, the highest up-regulated miRNA in ERα-positive compared to ERα-negative breast tumors, a new biomarker in breast cancers?

(2015) Geraldine Cizeron-Clairac et al.   BMC CANCER

miR-33a functions as a tumor suppressor in melanoma by targeting HIF-1α

(2015) Jianda Zhou et al.   CANCER BIOLOGY & THERAPY

MicroRNAs in pulmonary arterial hypertension: pathogenesis, diagnosis and treatment

(2015) Julie Bienertova-Vasku et al.   Journal of the American Society of Hypertension

Hypoxia-Inducible Factor-1 in Physiological and Pathophysiological Angiogenesis: Applications and Therapies

(2015) Agnieszka Zimna et al.   Biomed Research International

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

MicroRNA-18a Decreases Choroidal Endothelial Cell Proliferation and Migration by Inhibiting HIF1A Expression

(2015) Wei Jiang   MEDICAL SCIENCE MONITOR

MiR-335 Regulates Hif-1α to Reduce Cell Death in Both Mouse Cell Line and Rat Ischemic Models

(2015) Fu Jia Liu et al.   PLoS One

Upregulation of miR-184 Enhances the Malignant Biological Behavior of Human Glioma Cell Line A172 by Targeting FIH-1

(2014) Qinghua Yuan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Systematic Study of Drosophila MicroRNA Functions Using a Collection of Targeted Knockout Mutations

(2014) Ya-Wen Chen et al.   DEVELOPMENTAL CELL

A feedback regulatory loop between HIF-1α and miR-21 in response to hypoxia in cardiomyocytes

(2014) Yang Liu et al.   FEBS LETTERS

MicroRNA-190 Regulates Hypoxic Pulmonary Vasoconstriction by Targeting a Voltage-Gated K+Channel in Arterial Smooth Muscle Cells

(2014) Shan-Shan Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Circulating miRNA95 and miRNA190 Are Sensitive Markers for the Differential Diagnosis of Thyroid Nodules in a Caucasian Population

(2014) Silvia Cantara et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

miRDB: an online resource for microRNA target prediction and functional annotations

(2014) Nathan Wong et al.   NUCLEIC ACIDS RESEARCH

Up-Regulation of MicroRNA-190b Plays a Role for Decreased IGF-1 That Induces Insulin Resistance in Human Hepatocellular Carcinoma

(2014) Tzu-Min Hung et al.   PLoS One

MicroRNA-Mediated Regulation of Dp53 in the Drosophila Fat Body Contributes to Metabolic Adaptation to Nutrient Deprivation

(2014) Lara Barrio et al.   Cell Reports

microRNA-138 plays a role in hypoxic pulmonary vascular remodelling by targeting Mst1

(2013) Shanshan Li et al.   BIOCHEMICAL JOURNAL

Regulation of erythropoiesis by hypoxia-inducible factors

(2013) Volker H. Haase   BLOOD REVIEWS

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

(2013) Gregg L. Semenza   JOURNAL OF CLINICAL INVESTIGATION

NFκB1 (p50) suppresses SOD2 expression by inhibiting FoxO3a transactivation in a miR190/PHLPP1/Akt-dependent axis

(2013) Kejun Du et al.   MOLECULAR BIOLOGY OF THE CELL

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

NF-κB1 p50 promotes p53 protein translation through miR-190 downregulation of PHLPP1

(2013) Y Yu et al.   ONCOGENE

MiR-17 Partly Promotes Hematopoietic Cell Expansion through Augmenting HIF-1α in Osteoblasts

(2013) Yuxia Yang et al.   PLoS One

MicroRNAs

(2013) M. Bhaskaran et al.   VETERINARY PATHOLOGY

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

The Rectal Cancer microRNAome - microRNA Expression in Rectal Cancer and Matched Normal Mucosa

(2012) J. Gaedcke et al.   CLINICAL CANCER RESEARCH

A genome-wide transgenic resource for conditional expression of Drosophila microRNAs

(2012) F. Bejarano et al.   DEVELOPMENT

The updated biology of hypoxia-inducible factor

(2012) Samantha N Greer et al.   EMBO JOURNAL

The MicroRNA-328 Regulates Hypoxic Pulmonary Hypertension by Targeting at Insulin Growth Factor 1 Receptor and L-Type Calcium Channel-α1C

(2012) Lei Guo et al.   HYPERTENSION

Breast cancer signatures for invasiveness and prognosis defined by deep sequencing of microRNA

(2012) S. Volinia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

(2012) Gregg L. Semenza   TRENDS IN PHARMACOLOGICAL SCIENCES

Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways

(2011) Nadine Rohwer et al.   DRUG RESISTANCE UPDATES

A Hypoxia-Induced Positive Feedback Loop Promotes Hypoxia-Inducible Factor 1  Stability through miR-210 Suppression of Glycerol-3-Phosphate Dehydrogenase 1-Like

(2011) T. J. Kelly et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1  Activity during Prolonged Hypoxia

(2011) U. Bruning et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6

(2011) Ken Saito et al.   NUCLEIC ACIDS RESEARCH

miR-190-Mediated Downregulation of PHLPP Contributes to Arsenic-Induced Akt Activation and Carcinogenesis

(2011) Kevin Beezhold et al.   TOXICOLOGICAL SCIENCES

Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling

(2010) S. Rey et al.   CARDIOVASCULAR RESEARCH

miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity

(2010) M-P Puisségur et al.   CELL DEATH AND DIFFERENTIATION

Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis

(2010) Goutam Ghosh et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

miRBase: integrating microRNA annotation and deep-sequencing data

(2010) A. Kozomara et al.   NUCLEIC ACIDS RESEARCH

Oxygen Sensing in Drosophila: Multiple Isoforms of the Prolyl Hydroxylase Fatiga Have Different Capacity to Regulate HIFα/Sima

(2010) Julieta M. Acevedo et al.   PLoS One

Drosophila Genome-Wide RNAi Screen Identifies Multiple Regulators of HIF–Dependent Transcription in Hypoxia

(2010) Andrés Dekanty et al.   PLoS Genetics

Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

(2010) Doron Betel et al.   GENOME BIOLOGY

Downregulation of MiR-199a Derepresses Hypoxia-Inducible Factor-1α and Sirtuin 1 and Recapitulates Hypoxia Preconditioning in Cardiac Myocytes

(2009) Shweta Rane et al.   CIRCULATION RESEARCH

Regulation of Drosophila embryonic tracheogenesis by dVHL and hypoxia

(2009) Nathan T. Mortimer et al.   DEVELOPMENTAL BIOLOGY

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

Regulation of HIF-1α and VEGF by miR-20b Tunes Tumor Cells to Adapt to the Alteration of Oxygen Concentration

(2009) Zhang Lei et al.   PLoS One

Biology of HIF-1α

(2008) A Weidemann et al.   CELL DEATH AND DIFFERENTIATION

Cell Autonomy of HIF Effects in Drosophila: Tracheal Cells Sense Hypoxia and Induce Terminal Branch Sprouting

(2008) Lázaro Centanin et al.   DEVELOPMENTAL CELL

Profiling of 95 MicroRNAs in Pancreatic Cancer Cell Lines and Surgical Specimens by Real-Time PCR Analysis

(2008) Yuqing Zhang et al.   WORLD JOURNAL OF SURGERY