Intrinsic Noise Profoundly Alters the Dynamics and Steady State of Morphogen-Controlled Bistable Genetic Switches

DNA-Binding Kinetics Determines the Mechanism of Noise-Induced Switching in Gene Networks

(2015) Margaret J. Tse et al.   BIOPHYSICAL JOURNAL

Spatiotemporal Analysis of Different Mechanisms for Interpreting Morphogen Gradients

(2015) David M. Richards et al.   BIOPHYSICAL JOURNAL

Critical Timing without a Timer for Embryonic Development

(2015) Daniel E. Tufcea et al.   BIOPHYSICAL JOURNAL

Positional information and reaction-diffusion: two big ideas in developmental biology combine

(2015) J. B. A. Green et al.   DEVELOPMENT

Control of Stochastic and Induced Switching in Biophysical Networks

(2015) Daniel K. Wells et al.   Physical Review X

Classification of transient behaviours in a time-dependent toggle switch model

(2014) Berta Verd et al.   BMC Systems Biology

Encoding of Temporal Signals by the TGF-β Pathway and Implications for Embryonic Patterning

(2014) Benoit Sorre et al.   DEVELOPMENTAL CELL

Constructing the Energy Landscape for Genetic Switching System Driven by Intrinsic Noise

(2014) Cheng Lv et al.   PLoS One

Epigenetic state network approach for describing cell phenotypic transitions

(2014) P. Wang et al.   Interface Focus

Correction: Estimating the Stochastic Bifurcation Structure of Cellular Networks

(2014) Carl Song et al.   PLoS Computational Biology

Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers

(2013) Jian Shu et al.   CELL

Stochastic Stabilization of Phenotypic States: The Genetic Bistable Switch as a Case Study

(2013) Marc Weber et al.   PLoS One

How Cells Know Where They Are

(2013) A. D. Lander   SCIENCE

Quantifying Cell Fate Decisions for Differentiation and Reprogramming of a Human Stem Cell Network: Landscape and Biological Paths

(2013) Chunhe Li et al.   PLoS Computational Biology

Gene Regulatory Logic for Reading the Sonic Hedgehog Signaling Gradient in the Vertebrate Neural Tube

(2012) Nikolaos Balaskas et al.   CELL

A System of Repressor Gradients Spatially Organizes the Boundaries of Bicoid-Dependent Target Genes

(2012) Hongtao Chen et al.   CELL

A gene regulatory motif that generates oscillatory or multiway switch outputs

(2012) J. Panovska-Griffiths et al.   Journal of the Royal Society Interface

Type of noise defines global attractors in bistable molecular regulatory systems

(2012) Joanna Jaruszewicz et al.   JOURNAL OF THEORETICAL BIOLOGY

Noise drives sharpening of gene expression boundaries in the zebrafish hindbrain

(2012) Lei Zhang et al.   Molecular Systems Biology

Isolating intrinsic noise sources in a stochastic genetic switch

(2012) Jay M Newby   PHYSICAL BIOLOGY

Asymmetric Stochastic Switching Driven by Intrinsic Molecular Noise

(2012) David Frigola et al.   PLoS One

Thermodynamic State Ensemble Models of cis-Regulation

(2012) Marc S. Sherman et al.   PLoS Computational Biology

Mutual Repression Enhances the Steepness and Precision of Gene Expression Boundaries

(2012) Thomas R. Sokolowski et al.   PLoS Computational Biology

Cellular Decision Making and Biological Noise: From Microbes to Mammals

(2011) Gábor Balázsi et al.   CELL

Predicting embryonic patterning using mutual entropy fitness and in silico evolution

(2010) P. Francois et al.   DEVELOPMENT

Kinetic paths, time scale, and underlying landscapes: A path integral framework to study global natures of nonequilibrium systems and networks

(2010) Jin Wang et al.   JOURNAL OF CHEMICAL PHYSICS

Emerging properties of animal gene regulatory networks

(2010) Eric H. Davidson   NATURE

Understanding gene circuits at cell-fate branch points for rational cell reprogramming

(2010) Joseph X. Zhou et al.   TRENDS IN GENETICS

Cell Lineage Determination in State Space: A Systems View Brings Flexibility to Dogmatic Canonical Rules

(2010) Sui Huang   PLOS BIOLOGY

Stem Cell States, Fates, and the Rules of Attraction

(2009) Tariq Enver et al.   Cell Stem Cell

Visualization of Individual Scr mRNAs during Drosophila Embryogenesis Yields Evidence for Transcriptional Bursting

(2009) Adam Paré et al.   CURRENT BIOLOGY

The large deviation approach to statistical mechanics

(2009) Hugo Touchette   PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS

Canalization of Gene Expression in the Drosophila Blastoderm by Gap Gene Cross Regulation

(2009) Manu et al.   PLOS BIOLOGY

Uncoupling Time and Space in the Collinear Regulation of Hox Genes

(2009) Patrick Tschopp et al.   PLoS Genetics

Reaction Coordinates for the Flipping of Genetic Switches

(2008) Marco J. Morelli et al.   BIOPHYSICAL JOURNAL

Multistable Decision Switches for Flexible Control of Epigenetic Differentiation

(2008) Raúl Guantes et al.   PLoS Computational Biology