Inferring Growth Control Mechanisms in Growing Multi-cellular Spheroids of NSCLC Cells from Spatial-Temporal Image Data

Selecting Radiotherapy Dose Distributions by Means of Constrained Optimization Problems

(2014) J. C. L. Alfonso et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Rapid uptake of glucose and lactate, and not hypoxia, induces apoptosis in three-dimensional tumor tissue culture

(2014) Rachel W. Kasinskas et al.   Integrative Biology

A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane

(2014) Ying Chen et al.   International Journal for Numerical Methods in Biomedical Engineering

How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis

(2014) Dirk Drasdo et al.   JOURNAL OF HEPATOLOGY

Cyclin-Dependent Kinase Inhibitors as Marketed Anticancer Drugs: Where Are We Now? A Short Survey

(2014) Gaëlle Mariaule et al.   MOLECULES

MiR-449c targets c-Myc and inhibits NSCLC cell progression

(2013) Li-Jun Miao et al.   FEBS LETTERS

Development of a High-Throughput Three-Dimensional Invasion Assay for Anti-Cancer Drug Discovery

(2013) Nikki A. Evensen et al.   PLoS One

An Integrated Computational/Experimental Model of Lymphoma Growth

(2013) Hermann B. Frieboes et al.   PLoS Computational Biology

Cellular Potts Modeling of Tumor Growth, Tumor Invasion, and Tumor Evolution

(2013) András Szabó et al.   Frontiers in Oncology

Adenosine-5′-triphosphate up-regulates proliferation of human cardiac fibroblasts

(2012) Jing-Bo Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Three-dimensional cell culture: the missing link in drug discovery

(2012) Susan Breslin et al.   DRUG DISCOVERY TODAY

Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy

(2012) Geeta Mehta et al.   JOURNAL OF CONTROLLED RELEASE

Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): From microscopic measurements to macroscopic predictions of clinical progression

(2012) Paul Macklin et al.   JOURNAL OF THEORETICAL BIOLOGY

Modeling the impact of granular embedding media, and pulling versus pushing cells on growing cell clones

(2012) Dirk Drasdo et al.   NEW JOURNAL OF PHYSICS

Changes in Global Gene Expression Associated with 3D Structure of Tumors: An Ex Vivo Matrix-Free Mesothelioma Spheroid Model

(2012) Heungnam Kim et al.   PLoS One

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

Distinct caspase pathways mediate necrosis and apoptosis in subpopulations of hippocampal neurons after status epilepticus

(2010) Maria-Leonor Lopez-Meraz et al.   EPILEPSIA

Spatio-temporal cell dynamics in tumour spheroid irradiation

(2010) H. Kempf et al.   EUROPEAN PHYSICAL JOURNAL D

Multicellular tumor spheroids: An underestimated tool is catching up again

(2010) Franziska Hirschhaeuser et al.   JOURNAL OF BIOTECHNOLOGY

Biomechanical and Nutrient Controls in the Growth of Mammalian Cell Populations

(2010) STEFAN HOEHME et al.   Mathematical Population Studies

Aerobic growth at nanomolar oxygen concentrations

(2010) D. A. Stolper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration

(2010) S. Hoehme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrin signaling and lung cancer

(2010) Francesca Caccavari et al.   Cell Adhesion & Migration

Genomic and Expression Profiling of Glioblastoma Stem Cell-Like Spheroid Cultures Identifies Novel Tumor-Relevant Genes Associated with Survival

(2009) A. Ernst et al.   CLINICAL CANCER RESEARCH

Homeostatic competition drives tumor growth and metastasis nucleation

(2009) Markus Basan et al.   HFSP Journal

Image Guided Personalization of Reaction-Diffusion Type Tumor Growth Models Using Modified Anisotropic Eikonal Equations

(2009) E. Konukoglu et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

ATP controls cell cycle and induces proliferation in the mouse developing retina

(2009) Alfred Sholl-Franco et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Comparing the growth kinetics of cell populations in two and three dimensions

(2009) M. Radszuweit et al.   PHYSICAL REVIEW E

Modeling the Influence of the E-Cadherin-β-Catenin Pathway in Cancer Cell Invasion: A Multiscale Approach

(2008) Ignacio Ramis-Conde et al.   BIOPHYSICAL JOURNAL

Recent advances in three-dimensional multicellular spheroid culture for biomedical research

(2008) Ruei-Zhen Lin et al.   Biotechnology Journal

Multiphase modelling of tumour growth and extracellular matrix interaction: mathematical tools and applications

(2008) Luigi Preziosi et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Individual-based and continuum models of growing cell populations: a comparison

(2008) Helen Byrne et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Three-dimensional multispecies nonlinear tumor growth—I

(2008) S.M. Wise et al.   JOURNAL OF THEORETICAL BIOLOGY

Emergent vascular network inhomogeneities and resulting blood flow patterns in a growing tumor

(2007) M. Welter et al.   JOURNAL OF THEORETICAL BIOLOGY