Drosophila Wnt and STAT Define Apoptosis-Resistant Epithelial Cells for Tissue Regeneration after Irradiation

Epithelial Tumors Originate in Tumor Hotspots, a Tissue-Intrinsic Microenvironment

(2016) Yoichiro Tamori et al.   PLOS BIOLOGY

DuringDrosophiladisc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay

(2015) Tomonori Katsuyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tie-mediated signal from apoptotic cells protects stem cells in Drosophila melanogaster

(2015) Yalan Xing et al.   Nature Communications

Low Levels of p53 Protein and Chromatin Silencing of p53 Target Genes Repress Apoptosis in Drosophila Endocycling Cells

(2014) Bingqing Zhang et al.   PLoS Genetics

Dying Cells Protect Survivors from Radiation-Induced Cell Death in Drosophila

(2014) Amber Bilak et al.   PLoS Genetics

JAK/STAT signaling is required for hinge growth and patterning in the Drosophila wing disc

(2013) Aidee Ayala-Camargo et al.   DEVELOPMENTAL BIOLOGY

Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines

(2013) Hanneke Stegeman et al.   Molecular Cancer

The Development of a Monoclonal Antibody Recognizing the Drosophila melanogaster Phosphorylated Histone H2A Variant (γ-H2AV)

(2013) Cathleen M. Lake et al.   G3-Genes Genomes Genetics

Tissue Homeostasis in the Wing Disc of Drosophila melanogaster: Immediate Response to Massive Damage during Development

(2013) Salvador C. Herrera et al.   PLoS Genetics

Identification of a radiosensitivity signature using integrative metaanalysis of published microarray data for NCI-60 cancer cells

(2012) Han Sang Kim et al.   BMC GENOMICS

Activated STAT regulates growth and induces competitive interactions independently of Myc, Yorkie, Wingless and ribosome biogenesis

(2012) A. B. Rodrigues et al.   DEVELOPMENT

Inducible progenitor-derived Wingless regulates adult midgut regeneration inDrosophila

(2012) Julia B Cordero et al.   EMBO JOURNAL

Autocrine and paracrine unpaired signaling regulate intestinal stem cell maintenance and division

(2012) D. Osman et al.   JOURNAL OF CELL SCIENCE

Genome-Wide Expression Analysis Identifies a Modulator of Ionizing Radiation-Induced p53-Independent Apoptosis in Drosophila melanogaster

(2012) Petra van Bergeijk et al.   PLoS One

STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH+/CD133+ stem cell-like human colon cancer cells

(2011) Li Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells

(2011) Na Xu et al.   DEVELOPMENTAL BIOLOGY

Maintenance of imaginal disc plasticity and regenerative potential in Drosophila by p53

(2011) Brent S. Wells et al.   DEVELOPMENTAL BIOLOGY

Dynamic Coordination of Innate Immune Signaling and Insulin Signaling Regulates Systemic Responses to Localized DNA Damage

(2011) Jason Karpac et al.   DEVELOPMENTAL CELL

Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells

(2011) A. Edwards et al.   Disease Models & Mechanisms

E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila

(2010) Anita Wichmann et al.   DEVELOPMENTAL BIOLOGY

A Gene Expression Signature for Chemoradiosensitivity of Colorectal Cancer Cells

(2010) Melanie Spitzner et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

DNA damage signaling in response to double-strand breaks during mitosis

(2010) Simona Giunta et al.   JOURNAL OF CELL BIOLOGY

Heterochromatin silencing of p53 target genes by a small viral protein

(2010) Conrado Soria et al.   NATURE

Regulation of Drosophila melanogaster pro-apoptotic gene hid

(2009) Amber Bilak et al.   APOPTOSIS

Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

(2009) Huaqi Jiang et al.   CELL

Tissue Damage-Induced Intestinal Stem Cell Division in Drosophila

(2009) Alla Amcheslavsky et al.   Cell Stem Cell

Wingless signaling and the control of cell shape in Drosophila wing imaginal discs

(2009) Thomas J. Widmann et al.   DEVELOPMENTAL BIOLOGY

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

(2009) N. Buchon et al.   GENES & DEVELOPMENT

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

(2009) Sabrina L. Spencer et al.   NATURE

G-TRACE: rapid Gal4-based cell lineage analysis in Drosophila

(2009) Cory J Evans et al.   NATURE METHODS

Tumour-initiating cells: challenges and opportunities for anticancer drug discovery

(2009) Bin-Bing S. Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Genome-Wide RNAi Screen Identifies Genes Involved in Intestinal Pathogenic Bacterial Infection

(2009) S. J. F. Cronin et al.   SCIENCE

Radiosensitivity of Cancer-Initiating Cells and Normal Stem Cells (or what the Heisenberg Uncertainly Principle has to do with Biology)

(2009) Wendy Ann Woodward et al.   SEMINARS IN RADIATION ONCOLOGY

Paracrine Unpaired Signaling through the JAK/STAT Pathway Controls Self-renewal and Lineage Differentiation of Drosophila Intestinal Stem Cells

(2009) G. Lin et al.   Journal of Molecular Cell Biology

Regulation of apoptosis in Drosophila

(2008) H Steller   CELL DEATH AND DIFFERENTIATION

Regulation of apoptosis of rbf mutant cells during Drosophila development

(2008) Miho Tanaka-Matakatsu et al.   DEVELOPMENTAL BIOLOGY

Epigenetic Blocking of an Enhancer Region Controls Irradiation-Induced Proapoptotic Gene Expression in Drosophila Embryos

(2008) Yanping Zhang et al.   DEVELOPMENTAL CELL

Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells

(2008) Guonan Lin et al.   NATURE

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS

Regulation of DNA repair throughout the cell cycle

(2008) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

STAT92E is a positive regulator of Drosophila inhibitor of apoptosis 1 (DIAP/1) and protects against radiation-induced apoptosis

(2008) A. Betz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

E2F and p53 Induce Apoptosis Independently during Drosophila Development but Intersect in the Context of DNA Damage

(2008) Nam-Sung Moon et al.   PLoS Genetics