Dihydrostreptomycin Directly Binds to, Modulates, and Passes through the MscL Channel Pore

Mechanical coupling of the multiple structural elements of the large-conductance mechanosensitive channel during expansion

(2015) Jie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel method for the study of molecular interaction by using microscale thermophoresis

(2015) Yexuan Mao et al.   TALANTA

Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations

(2015) Irene Iscla et al.   PLoS One

Lipid14: The Amber Lipid Force Field

(2014) Callum J. Dickson et al.   Journal of Chemical Theory and Computation

MicroScale Thermophoresis: Interaction analysis and beyond

(2014) Moran Jerabek-Willemsen et al.   JOURNAL OF MOLECULAR STRUCTURE

Streptomycin potency is dependent on MscL channel expression

(2014) Irene Iscla et al.   Nature Communications

Phosphatidylinositol Is Crucial for the Mechanosensitivity of Mycobacterium tuberculosis MscL

(2013) Dalian Zhong et al.   BIOCHEMISTRY

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald

(2013) Romelia Salomon-Ferrer et al.   Journal of Chemical Theory and Computation

Structure and stability of the C-terminal helical bundle of theE. colimechanosensitive channel of large conductance

(2013) Troy A. Walton et al.   PROTEIN SCIENCE

Sensing and Responding to Membrane Tension: The Bacterial MscL Channel as a Model System

(2012) Irene Iscla et al.   BIOPHYSICAL JOURNAL

The dynamics of protein-protein interactions between domains of MscL at the cytoplasmic-lipid interface

(2012) Irene Iscla et al.   Channels

The gating mechanism of the bacterial mechanosensitive channel MscL revealed by molecular dynamics simulations

(2012) Yasuyuki Sawada et al.   Channels

The MscS and MscL Families of Mechanosensitive Channels Act as Microbial Emergency Release Valves

(2012) Ian R. Booth et al.   JOURNAL OF BACTERIOLOGY

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 1. Generalized Born

(2012) Andreas W. Götz et al.   Journal of Chemical Theory and Computation

Structural Investigation of MscL Gating Using Experimental Data and Coarse Grained MD Simulations

(2012) Evelyne Deplazes et al.   PLoS Computational Biology

Three Routes To Modulate the Pore Size of the MscL Channel/Nanovalve

(2011) Li-Min Yang et al.   ACS Nano

An in vivo screen reveals protein-lipid interactions crucial for gating a mechanosensitive channel

(2010) Irene Iscla et al.   FASEB JOURNAL

An improved open-channel structure of MscL determined from FRET confocal microscopy and simulation

(2010) Ben Corry et al.   JOURNAL OF GENERAL PHYSIOLOGY

YbdG inEscherichia coliis a threshold-setting mechanosensitive channel with MscM activity

(2010) Ulrike Schumann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluating the Performance of the ff99SB Force Field Based on NMR Scalar Coupling Data

(2009) Lauren Wickstrom et al.   BIOPHYSICAL JOURNAL

An open-pore structure of the mechanosensitive channel MscL derived by determining transmembrane domain interactions upon gating

(2009) Yuezhou Li et al.   FASEB JOURNAL

Gating of the Mechanosensitive Channel Protein MscL: The Interplay of Membrane and Protein

(2008) Jonggu Jeon et al.   BIOPHYSICAL JOURNAL

On the Structure of the N-Terminal Domain of the MscL Channel: Helical Bundle or Membrane Interface

(2008) Irene Iscla et al.   BIOPHYSICAL JOURNAL