Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations

K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac

(2015) Y. Y. Dong et al.   SCIENCE

Electrostatics at the membrane define MscL channel mechanosensitivity and kinetics

(2014) Dalian Zhong et al.   FASEB JOURNAL

Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel

(2014) Stephen G. Brohawn et al.   NATURE

Feeling the hidden mechanical forces in lipid bilayer is an original sense

(2014) A. Anishkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel

(2013) S. G. Brohawn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chimeras Reveal a Single Lipid-Interface Residue that Controls MscL Channel Kinetics as well as Mechanosensitivity

(2013) Li-Min Yang et al.   Cell Reports

Sensing and Responding to Membrane Tension: The Bacterial MscL Channel as a Model System

(2012) Irene Iscla et al.   BIOPHYSICAL JOURNAL

The dynamics of protein-protein interactions between domains of MscL at the cytoplasmic-lipid interface

(2012) Irene Iscla et al.   Channels

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K+ Ion Channel

(2012) S. G. Brohawn et al.   SCIENCE

Three Routes To Modulate the Pore Size of the MscL Channel/Nanovalve

(2011) Li-Min Yang et al.   ACS Nano

An in vivo screen reveals protein-lipid interactions crucial for gating a mechanosensitive channel

(2010) Irene Iscla et al.   FASEB JOURNAL

An improved open-channel structure of MscL determined from FRET confocal microscopy and simulation

(2010) Ben Corry et al.   JOURNAL OF GENERAL PHYSIOLOGY

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Conserved motifs in mechanosensitive channels MscL and MscS

(2009) Daniel Balleza et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

An open-pore structure of the mechanosensitive channel MscL derived by determining transmembrane domain interactions upon gating

(2009) Yuezhou Li et al.   FASEB JOURNAL

Gating of the Mechanosensitive Channel Protein MscL: The Interplay of Membrane and Protein

(2008) Jonggu Jeon et al.   BIOPHYSICAL JOURNAL

On the Structure of the N-Terminal Domain of the MscL Channel: Helical Bundle or Membrane Interface

(2008) Irene Iscla et al.   BIOPHYSICAL JOURNAL