Cerebrospinal Fluid Aβ42Levels: When Physiological Become Pathological State

Atherosclerosis in the Evolution of Alzheimer's Disease: Can Treatment Reduce Cognitive Decline?

(2017) Simona Luzzi et al.   JOURNAL OF ALZHEIMERS DISEASE

Biomarkers of Alzheimer's disease and mild cognitive impairment: A current perspective

(2015) Piotr Lewczuk et al.   Advances in Medical Sciences

Ribosylation triggering Alzheimer's disease-like Tau hyperphosphorylation via activation of CaMKII

(2015) Yan Wei et al.   AGING CELL

Amyloid β oligomers induce interleukin-1β production in primary microglia in a cathepsin B- and reactive oxygen species-dependent manner

(2015) Jun Taneo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer’s disease

(2015) Alaina Baker-Nigh et al.   BRAIN

Formaldehyde as a trigger for protein aggregation and potential target for mitigation of age-related, progressive cognitive impairment

(2015) Tao Su et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Alzheimer-associated A  oligomers impact the central nervous system to induce peripheral metabolic deregulation

(2015) J. R. Clarke et al.   EMBO Molecular Medicine

Depressive symptoms accelerate cognitive decline in amyloid-positive MCI patients

(2015) Matthias Brendel et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Amyloid β peptide directly impairs pineal gland melatonin synthesis and melatonin receptor signaling through the ERK pathway

(2015) Erika Cecon et al.   FASEB JOURNAL

Neuroinflammatory Signals in Alzheimer Disease and APP/PS1 Transgenic Mice

(2015) Irene López-González et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Brain Amyloid-  Burden Is Associated with Disruption of Intrinsic Functional Connectivity within the Medial Temporal Lobe in Cognitively Normal Elderly

(2015) Z. Song et al.   JOURNAL OF NEUROSCIENCE

Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

(2015) Erik S Musiek et al.   NATURE NEUROSCIENCE

Amyloid biomarkers in Alzheimer's disease

(2015) Kaj Blennow et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Amyloid-β, Anxiety, and Cognitive Decline in Preclinical Alzheimer Disease

(2015) Robert H. Pietrzak et al.   JAMA Psychiatry

Amyloid β-peptide-dependent activation of human platelets: essential role for Ca2+and ADP in aggregation and thrombus formation

(2014) Ilaria Canobbio et al.   BIOCHEMICAL JOURNAL

Signaling pathway cross talk in Alzheimer’s disease

(2014) Juan A Godoy et al.   Cell Communication and Signaling

Pre-activated blood platelets and a pro-thrombotic phenotype in APP23 mice modeling Alzheimer's disease

(2014) Andrea Jarre et al.   CELLULAR SIGNALLING

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer’s disease

(2014) Jee Hoon Roh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Models of β-amyloid induced Tau-pathology: the long and “folded” road to understand the mechanism

(2014) Ilie-Cosmin Stancu et al.   Molecular Neurodegeneration

Neural compensation in older people with brain amyloid-β deposition

(2014) Jeremy A Elman et al.   NATURE NEUROSCIENCE

Dopaminergic Modulation of Cortical Plasticity in Alzheimer’s Disease Patients

(2014) Giacomo Koch et al.   NEUROPSYCHOPHARMACOLOGY

Blood Platelets in the Progression of Alzheimer’s Disease

(2014) Nina S. Gowert et al.   PLoS One

D-ribosylation induces cognitive impairment through RAGE-dependent astrocytic inflammation

(2014) C Han et al.   Cell Death & Disease

Orexinergic System Dysregulation, Sleep Impairment, and Cognitive Decline in Alzheimer Disease

(2014) Claudio Liguori et al.   JAMA Neurology

The Preclinical Alzheimer Cognitive Composite

(2014) Michael C. Donohue et al.   JAMA Neurology

Synergistic Effect of β-Amyloid and Neurodegeneration on Cognitive Decline in Clinically Normal Individuals

(2014) Elizabeth C. Mormino et al.   JAMA Neurology

Longitudinal change in CSF Tau and Aβ biomarkers for up to 48 months in ADNI

(2013) Jon B. Toledo et al.   ACTA NEUROPATHOLOGICA

The effect of amyloid β on cognitive decline is modulated by neural integrity in cognitively normal elderly

(2013) Miranka Wirth et al.   Alzheimers & Dementia

Formaldehyde induces hyperphosphorylation and polymerization of Tau protein both in vitro and in vivo

(2013) Jing Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Brain amyloid-β oligomers in ageing and Alzheimer’s disease

(2013) Sylvain E. Lesné et al.   BRAIN

Frailty Among Alzheimer’s Disease Patients

(2013) Giacomo Koch et al.   CNS & Neurological Disorders-Drug Targets

Detection of β-amyloid oligomers as a predictor of neurological outcome after brain injury

(2013) Joshua Wayne Gatson et al.   JOURNAL OF NEUROSURGERY

Effect of α-Synuclein on Amyloid β-Induced Toxicity: Relevance to Lewy Body Variant of Alzheimer Disease

(2013) Rosa Resende et al.   NEUROCHEMICAL RESEARCH

Ascending monoaminergic systems alterations in Alzheimer's disease. Translating basic science into clinical care

(2013) Ludwig Trillo et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Proteolytically Inactive Insulin-Degrading Enzyme Inhibits Amyloid Formation Yielding Non-Neurotoxic Aβ Peptide Aggregates

(2013) Matias B. de Tullio et al.   PLoS One

Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine - searching for the connections

(2012) Wojciech Danysz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Brain Insulin Resistance and Deficiency as Therapeutic Targets in Alzheimers Disease

(2012) Suzanne M. de la Monte   Current Alzheimer Research

Cerebrospinal fluid levels of Aβ42 relationship with cholinergic cortical activity in Alzheimer’s disease patients

(2012) Alessandro Martorana et al.   JOURNAL OF NEURAL TRANSMISSION

Remodeling of axo-spinous synapses in the pathophysiology and treatment of depression

(2012) P. Licznerski et al.   NEUROSCIENCE

Heterogeneity of elderly depression: Increased risk of Alzheimer's disease and Aβ protein metabolism

(2012) Yuki Namekawa et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Insulin resistance and Alzheimer's disease

(2011) Suzanne M. De La Monte   BMB Reports

Soluble A  Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors

(2011) S. Li et al.   JOURNAL OF NEUROSCIENCE

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

The Upside of APP at Synapses

(2010) Hyang-Sook Hoe et al.   CNS Neuroscience & Therapeutics

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease

(2009) Robert D. Bell et al.   ACTA NEUROPATHOLOGICA

CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment

(2009) Niklas Mattsson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Picomolar Amyloid-  Positively Modulates Synaptic Plasticity and Memory in Hippocampus

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

CSF biomarkers in relationship to cognitive profiles in Alzheimer disease

(2009) A. E. van der Vlies et al.   NEUROLOGY

CSF biomarkers predict rate of cognitive decline in Alzheimer disease

(2009) M. I. Kester et al.   NEUROLOGY

Dopamine Modulates Cholinergic Cortical Excitability in Alzheimer's Disease Patients

(2009) Alessandro Martorana et al.   NEUROPSYCHOPHARMACOLOGY

SYMPOSIUM: Clearance of Aβ from the Brain in Alzheimer's Disease: Aβ-Degrading Enzymes in Alzheimer's Disease

(2008) James Scott Miners et al.   BRAIN PATHOLOGY

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE