Reactive oxygen species drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels

Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms

(2016) Song Lin Chua et al.   Nature Communications

PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix

(2015) Shan Yu et al.   CELL RESEARCH

Systematic Nomenclature for GGDEF and EAL Domain-Containing Cyclic Di-GMP Turnover Proteins of Escherichia coli: TABLE 1

(2015) Regine Hengge et al.   JOURNAL OF BACTERIOLOGY

The Cyclic AMP-Vfr Signaling Pathway in Pseudomonas aeruginosa Is Inhibited by Cyclic Di-GMP

(2015) Henrik Almblad et al.   JOURNAL OF BACTERIOLOGY

In vitro and in vivo generation and characterization of Pseudomonas aeruginosa biofilm–dispersed cells via c-di-GMP manipulation

(2015) Song Lin Chua et al.   Nature Protocols

Constitutive production of c-di-GMP is associated with mutations in a variant ofPseudomonas aeruginosawith altered membrane composition

(2015) Andrea Blanka et al.   Science Signaling

Multiple diguanylate cyclase-coordinated regulation of pyoverdine synthesis inPseudomonas aeruginosa

(2015) Yicai Chen et al.   Environmental Microbiology Reports

C-di-GMP regulates Pseudomonas aeruginosa stress response to tellurite during both planktonic and biofilm modes of growth

(2015) Song Lin Chua et al.   Scientific Reports

Constitutive production of c-di-GMP is associated with mutations in a variant ofPseudomonas aeruginosawith altered membrane composition

(2015) Andrea Blanka et al.   Science Signaling

Cyclic Di-GMP-Mediated Repression of Swarming Motility by Pseudomonas aeruginosa PA14 Requires the MotAB Stator

(2014) S. L. Kuchma et al.   JOURNAL OF BACTERIOLOGY

Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis

(2014) Rasmus Lykke Marvig et al.   NATURE GENETICS

Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles

(2014) Song Lin Chua et al.   Nature Communications

Pseudomonas aeruginosa eradicates Staphylococcus aureus by manipulating the host immunity

(2014) Erwan Pernet et al.   Nature Communications

The Pseudomonas aeruginosa Type III Translocon Is Required for Biofilm Formation at the Epithelial Barrier

(2014) Cindy S. Tran et al.   PLoS Pathogens

Extracellular DNA Shields against Aminoglycosides in Pseudomonas aeruginosa Biofilms

(2013) Wen-Chi Chiang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bis-(3′-5′)-Cyclic Dimeric GMP Regulates Antimicrobial Peptide Resistance in Pseudomonas aeruginosa

(2013) Song Lin Chua et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Gac/Rsm and cyclic-di-GMP signalling networks coordinately regulate iron uptake inPseudomonas aeruginosa

(2013) Emanuela Frangipani et al.   ENVIRONMENTAL MICROBIOLOGY

Biofilm Formation Avoids Complement Immunity and Phagocytosis of Streptococcus pneumoniae

(2013) Mirian Domenech et al.   INFECTION AND IMMUNITY

ROS production in phagocytes: why, when, and where?

(2013) Sophie Dupré-Crochet et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger

(2013) U. Romling et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Extracellular Matrix Component Psl Provides Fast-Acting Antibiotic Defense in Pseudomonas aeruginosa Biofilms

(2013) Nicole Billings et al.   PLoS Pathogens

Fluorescence-Based Reporter for Gauging Cyclic Di-GMP Levels in Pseudomonas aeruginosa

(2012) Morten T. Rybtke et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Multiple antibiotic-resistant Pseudomonas aeruginosa and lung function decline in patients with cystic fibrosis

(2012) Clement L. Ren et al.   Journal of Cystic Fibrosis

Self-produced exopolysaccharide is a signal that stimulates biofilm formation in Pseudomonas aeruginosa

(2012) Y. Irie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomics of Adaptation during Experimental Evolution of the Opportunistic Pathogen Pseudomonas aeruginosa

(2012) Alex Wong et al.   PLoS Genetics

Oxidative stress and antioxidant therapy in cystic fibrosis

(2011) Francesco Galli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Evolutionary dynamics of bacteria in a human host environment

(2011) L. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GGDEF proteins YeaI, YedQ, and YfiN reduce early biofilm formation and swimming motility in Escherichia coli

(2010) Viviana Sanchez-Torres et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Metabolic Network Analysis of Pseudomonas aeruginosa during Chronic Cystic Fibrosis Lung Infection

(2010) M. A. Oberhardt et al.   JOURNAL OF BACTERIOLOGY

Pseudomonas aeruginosa biofilm matrix polysaccharide Psl is regulated transcriptionally by RpoS and post-transcriptionally by RsmA

(2010) Yasuhiko Irie et al.   MOLECULAR MICROBIOLOGY

Pseudomonas aeruginosauses a cyclic-di-GMP-regulated adhesin to reinforce the biofilm extracellular matrix

(2010) Bradley R. Borlee et al.   MOLECULAR MICROBIOLOGY

Parallel Evolution in Pseudomonas aeruginosa over 39,000 Generations In Vivo

(2010) H. K. Huse et al.   mBio

Antibiotic Resistance in Pseudomonas aeruginosa Strains with Increased Mutation Frequency Due to Inactivation of the DNA Oxidative Repair System

(2009) L. F. Mandsberg et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pseudomonas aeruginosa Rugose Small-Colony Variants Have Adaptations That Likely Promote Persistence in the Cystic Fibrosis Lung

(2009) M. Starkey et al.   JOURNAL OF BACTERIOLOGY

Principles of c-di-GMP signalling in bacteria

(2009) Regine Hengge   NATURE REVIEWS MICROBIOLOGY

Pseudomonas aeruginosabiofilms in the respiratory tract of cystic fibrosis patients

(2009) Thomas Bjarnsholt et al.   PEDIATRIC PULMONOLOGY

Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

(2009) M Kolpen et al.   THORAX

Assembly and Development of the Pseudomonas aeruginosa Biofilm Matrix

(2009) Luyan Ma et al.   PLoS Pathogens

Inverse regulatory coordination of motility and curli-mediated adhesion in Escherichia coli

(2008) C. Pesavento et al.   GENES & DEVELOPMENT