Novel GM-CSF-based vaccines: One small step in GM-CSF gene optimization, one giant leap for human vaccines

The efficacy of a novel vaccine approach using tumor cells that ectopically express a codon-optimized murine GM-CSF in a murine tumor model

(2016) Chu-Chi Lin et al.   VACCINE

Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes–Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer

(2015) Dung T. Le et al.   JOURNAL OF CLINICAL ONCOLOGY

G-CSF and GM-CSF in Neutropenia

(2015) Hrishikesh M. Mehta et al.   JOURNAL OF IMMUNOLOGY

Safety and immunologic correlates of Melanoma GVAX, a GM-CSF secreting allogeneic melanoma cell vaccine administered in the adjuvant setting

(2015) Evan J Lipson et al.   Journal of Translational Medicine

A Review of GM-CSF Therapy in Sepsis

(2015) Brittany Mathias et al.   MEDICINE

Targeting GM-CSF in inflammatory diseases

(2015) Ian P. Wicks et al.   Nature Reviews Rheumatology

Parallels between Cancer and Infectious Disease

(2014) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase II Trial of Neoadjuvant Docetaxel and CG1940/CG8711 Followed by Radical Prostatectomy in Patients With High-Risk Clinically Localized Prostate Cancer

(2013) J. Vuky et al.   ONCOLOGIST

How I treat acquired aplastic anemia

(2012) P. Scheinberg et al.   BLOOD

Cancer-Related Inflammation

(2012) Juliana Candido et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Persistent inflammation and immunosuppression

(2012) Lori F. Gentile et al.   Journal of Trauma and Acute Care Surgery

Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial

(2012) Alfons JM van den Eertwegh et al.   LANCET ONCOLOGY

A randomized controlled study in patients with newly diagnosed severe aplastic anemia receiving antithymocyte globulin (ATG), cyclosporine, with or without G-CSF: a study of the SAA Working Party of the European Group for Blood and Marrow Transplantation

(2011) A. Tichelli et al.   BLOOD

A Live-Attenuated Listeria Vaccine (ANZ-100) and a Live-Attenuated Listeria Vaccine Expressing Mesothelin (CRS-207) for Advanced Cancers: Phase I Studies of Safety and Immune Induction

(2011) D. T. Le et al.   CLINICAL CANCER RESEARCH

Phase I Trial of “bi-shRNAifurin/GMCSF DNA/Autologous Tumor Cell” Vaccine (FANG) in Advanced Cancer

(2011) Neil Senzer et al.   MOLECULAR THERAPY

Assessing oncologic benefit in clinical trials of immunotherapy agents

(2010) R. K. Hales et al.   ANNALS OF ONCOLOGY

Treatment with GM-CSF Secreting Myeloid Leukemia Cell Vaccine Prior to Autologous-BMT Improves the Survival of Leukemia-Challenged Mice

(2010) Jenny Zilberberg et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock

(2010) Caroline Landelle et al.   INTENSIVE CARE MEDICINE

Autologous tumor cell vaccination plus infusion of GM-CSF by a programmable pump in the treatment of recurrent malignant gliomas

(2010) Anne Clavreul et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Enhancing therapy of B16F10 melanoma efficacy through tumor vaccine expressing GPI-anchored IL-21 and secreting GM-CSF in mouse model

(2010) Fengshu Zhao et al.   VACCINE

A novel therapeutic vaccine of GM-CSF/TNFα surface-modified RM-1 cells against the orthotopic prostatic cancer

(2010) Weihua Yin et al.   VACCINE

Granulocyte–Macrophage Colony-stimulating Factor to Reverse Sepsis-associated Immunosuppression

(2009) Christian Meisel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Timed Sequential Treatment With Cyclophosphamide, Doxorubicin, and an Allogeneic Granulocyte-Macrophage Colony-Stimulating Factor–Secreting Breast Tumor Vaccine: A Chemotherapy Dose-Ranging Factorial Study of Safety and Immune Activation

(2009) Leisha A. Emens et al.   JOURNAL OF CLINICAL ONCOLOGY

Synergy Between Dendritic Cells and GM–CSF-secreting Tumor Cells for the Treatment of a Murine Renal Cell Carcinoma

(2009) Gregory Driessens et al.   JOURNAL OF IMMUNOTHERAPY

G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis

(2009) Ann L. Cornish et al.   Nature Reviews Rheumatology

Vaccines for the Treatment of Non-Small Cell Lung Cancer: A Renewed Anticancer Strategy

(2009) C. Gridelli et al.   ONCOLOGIST

Allogeneic Granulocyte Macrophage Colony-Stimulating Factor-Secreting Tumor Immunotherapy Alone or in Sequence with Cyclophosphamide for Metastatic Pancreatic Cancer: A Pilot Study of Safety, Feasibility, and Immune Activation

(2008) D. Laheru et al.   CLINICAL CANCER RESEARCH