Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease

Alzheimer disease: modeling an Aβ-centered biological network

(2016) D Campion et al.   MOLECULAR PSYCHIATRY

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementia

(2015) Panos Roussos et al.   Alzheimers & Dementia

Pathophysiology of Hypoperfusion of the Precuneus in Early Alzheimer's Disease

(2015) J. Scott Miners et al.   BRAIN PATHOLOGY

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

Understanding multicellular function and disease with human tissue-specific networks

(2015) Casey S Greene et al.   NATURE GENETICS

A survey of human brain transcriptome diversity at the single cell level

(2015) Spyros Darmanis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer’s disease

(2014) Yasuko Kitagishi et al.   Alzheimers Research & Therapy

Genetics of Alzheimer Disease

(2013) A.T. Rao et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease

(2013) Usman A Khan et al.   NATURE NEUROSCIENCE

A preliminary study of the whole-genome expression profile of sporadic and monogenic early-onset Alzheimer's disease

(2013) Anna Antonell et al.   NEUROBIOLOGY OF AGING

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

(2013) Ana Griciuc et al.   NEURON

Review: The genetics of Alzheimer's disease; putting flesh on the bones

(2013) C. Medway et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

A System-Level Transcriptomic Analysis of Schizophrenia Using Postmortem Brain Tissue Samples

(2012) Panos Roussos et al.   ARCHIVES OF GENERAL PSYCHIATRY

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Complement receptor 1 (CR1) and Alzheimer's disease

(2011) Helen Crehan et al.   IMMUNOBIOLOGY

A novel potent tumour promoter aberrantly overexpressed in most human cancers

(2011) Atsushi Takahashi et al.   Scientific Reports

Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target

(2010) Maya K. Desai et al.   AMERICAN JOURNAL OF PATHOLOGY

Analysis of Alzheimer's disease severity across brain regions by topological analysis of gene co-expression networks

(2010) Monika Ray et al.   BMC Systems Biology

Functional Genomics of Brain Aging and Alzheimers Disease: Focus on Selective Neuronal Vulnerability

(2010) Xinkun Wang et al.   CURRENT GENOMICS

Current status on Alzheimer disease molecular genetics: from past, to present, to future

(2010) K. Bettens et al.   HUMAN MOLECULAR GENETICS

Transcriptional profile of Parkinson blood mononuclear cells with LRRK2 mutation

(2010) Eugénie Mutez et al.   NEUROBIOLOGY OF AGING

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

(2009) Paula I. Moreira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Myelin Gene Regulatory Factor Is a Critical Transcriptional Regulator Required for CNS Myelination

(2009) Ben Emery et al.   CELL

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

(2009) Frank Soldner et al.   CELL

Molecular networks as sensors and drivers of common human diseases

(2009) Eric E. Schadt   NATURE

Gain in Brain Immunity in the Oldest-Old Differentiates Cognitively Normal from Demented Individuals

(2009) Pavel Katsel et al.   PLoS One

Cytoskeletal pathologies of Alzheimer disease

(2009) James R. Bamburg et al.   CELL MOTILITY AND THE CYTOSKELETON

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Reassessing the amyloid cascade hypothesis of Alzheimer's disease

(2008) Sanjay W. Pimplikar   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set

(2008) Winnie S. Liang et al.   PHYSIOLOGICAL GENOMICS

Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

(2008) Corneliu Henegar et al.   GENOME BIOLOGY

Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia

(2007) Vahram Haroutunian et al.   NEUROBIOLOGY OF AGING