Aging Shapes the Population-Mean and -Dispersion of Gene Expression in Human Brains

Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk

(2016) Mark T.W. Ebbert et al.   Alzheimers & Dementia

A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood

(2016) Jing Zhao et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Whole-Genome Sequencing of a Healthy Aging Cohort

(2016) Galina A. Erikson et al.   CELL

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Global genome splicing analysis reveals an increased number of alternatively spliced genes with aging

(2015) Sofía A. Rodríguez et al.   AGING CELL

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

(2015) Latarsha J. Carithers et al.   BIOPRESERVATION AND BIOBANKING

Novel humanABCC9/SUR2brain-expressed transcripts and an eQTL relevant to hippocampal sclerosis of aging

(2015) Peter T. Nelson et al.   JOURNAL OF NEUROCHEMISTRY

Coexpression networks identify brain region–specific enhancer RNAs in the human brain

(2015) Pu Yao et al.   NATURE NEUROSCIENCE

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

The transcriptional landscape of age in human peripheral blood

(2015) Marjolein J. Peters et al.   Nature Communications

A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project

(2015) Latarsha J. Carithers et al.   Biopreservation and Biobanking

Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

(2015) Jialiang Yang et al.   Scientific Reports

Pathway-Based Factor Analysis of Gene Expression Data Produces Highly Heritable Phenotypes That Associate with Age

(2015) Andrew Anand Brown et al.   G3-Genes Genomes Genetics

Aberrant Gene Expression in Humans

(2015) Yong Zeng et al.   PLoS Genetics

IL7R gene expression network associates with human healthy ageing

(2015) Willemijn M. Passtoors et al.   Immunity & Ageing

The developmental transcriptome of the human brain

(2014) Andrew T.N. Tebbenkamp et al.   CURRENT OPINION IN NEUROLOGY

Transcriptional landscape of the prenatal human brain

(2014) Jeremy A. Miller et al.   NATURE

A common GSAP promoter variant contributes to Alzheimer's disease liability

(2014) Min Zhu et al.   NEUROBIOLOGY OF AGING

Additive, Epistatic, and Environmental Effects Through the Lens of Expression Variability QTL in a Twin Cohort

(2013) G. Wang et al.   GENETICS

A Dramatic Increase of C1q Protein in the CNS during Normal Aging

(2013) A. H. Stephan et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

(2013) Petroula Proitsi et al.   NEUROBIOLOGY OF AGING

TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres

(2013) Jiangguo Lin et al.   NUCLEIC ACIDS RESEARCH

Gene expression changes with age in skin, adipose tissue, blood and brain

(2013) Daniel Glass et al.   GENOME BIOLOGY

Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes

(2012) Atsuhiko T. Naito et al.   CELL

Non-formalin fixative versus formalin-fixed tissue: A comparison of histology and RNA quality

(2012) Daniel Groelz et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Genetic Variants Contribute to Gene Expression Variability in Humans

(2012) A. M. Hulse et al.   GENETICS

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

(2012) Oliver Stegle et al.   Nature Protocols

Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain

(2012) Dena G. Hernandez et al.   NEUROBIOLOGY OF DISEASE

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

A genome-wide association study of aging

(2011) Stefan Walter et al.   NEUROBIOLOGY OF AGING

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

Rare and Common Regulatory Variation in Population-Scale Sequenced Human Genomes

(2011) Stephen B. Montgomery et al.   PLoS Genetics

Joint Genetic Analysis of Gene Expression Data with Inferred Cellular Phenotypes

(2011) Leopold Parts et al.   PLoS Genetics

Chromatin structure as a mediator of aging

(2010) Jason Feser et al.   FEBS LETTERS

Genetic Variability in CLU and Its Association with Alzheimer's Disease

(2010) Rita J. Guerreiro et al.   PLoS One

Aging Mice Show a Decreasing Correlation of Gene Expression within Genetic Modules

(2009) Lucinda K. Southworth et al.   PLoS Genetics

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

(2008) Daniel G Healy et al.   LANCET NEUROLOGY

Functional organization of the transcriptome in human brain

(2008) Michael C Oldham et al.   NATURE NEUROSCIENCE

p73 Regulates Neurodegeneration and Phospho-Tau Accumulation during Aging and Alzheimer's Disease

(2008) Monica K. Wetzel et al.   NEURON

Age-Dependent Variability in Gene Expression in Male Fischer 344 Rat Retina

(2008) Zhen Li et al.   TOXICOLOGICAL SCIENCES