PEDF and its roles in physiological and pathological conditions: implication in diabetic and hypoxia-induced angiogenic diseases
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
PEDF and its roles in physiological and pathological conditions: implication in diabetic and hypoxia-induced angiogenic diseases
Authors
Keywords
-
Journal
CLINICAL SCIENCE
Volume 128, Issue 11, Pages 805-823
Publisher
Portland Press Ltd.
Online
2015-03-20
DOI
10.1042/cs20130463
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration
- (2016) Shozo Sonoda et al. Aging-US
- Pigment Epithelium-Derived Factor Blocks Tumor Extravasation by Suppressing Amoeboid Morphology and Mesenchymal Proteolysis
- (2015) Omar Ladhani et al. NEOPLASIA
- A NovelIFITM5Mutation in Severe Atypical Osteogenesis Imperfecta Type VI Impairs Osteoblast Production of Pigment Epithelium-Derived Factor
- (2014) Charles R Farber et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Normal Bone Density and Fat Mass in HeterozygousSERPINF1Mutation Carriers
- (2014) Hadil Al-Jallad et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Elevated Circulating Pigment Epithelium-Derived Factor Predicts the Progression of Diabetic Nephropathy in Patients With Type 2 Diabetes
- (2014) Elaine Hui et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Clinical correlates of serum pigment epithelium-derived factor in type 2 diabetes patients
- (2014) Alicia J. Jenkins et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- Hormonal regulation of pigment epithelium-derived factor (PEDF) expression in the endometrium
- (2014) Dana Chuderland et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Regulatory and Functional Connection of Microphthalmia-Associated Transcription Factor and Anti-Metastatic Pigment Epithelium Derived Factor in Melanoma
- (2014) Asunción Fernández-Barral et al. NEOPLASIA
- PEDF expression regulates the proangiogenic and proinflammatory phenotype of the lung endothelium
- (2013) Eui Seok Shin et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Pigment epithelium-derived factor (PEDF) binds to caveolin-1 and inhibits the pro-inflammatory effects of caveolin-1 in endothelial cells
- (2013) Takanori Matsui et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- VEGF Secreted by Hypoxic Muller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy
- (2013) M. Rodrigues et al. DIABETES
- Determination of mesenchymal stem cell fate by pigment epithelium-derived factor (PEDF) results in increased adiposity and reduced bone mineral content
- (2013) Arijeet K. Gattu et al. FASEB JOURNAL
- Inhibition of Corneal Neovascularization with the Combination of Bevacizumab and Plasmid Pigment Epithelium-Derived Factor-Synthetic Amphiphile INTeraction-18 (p-PEDF-SAINT-18) Vector in a Rat Corneal Experimental Angiogenesis Model
- (2013) Chien-Neng Kuo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Liver, but not adipose tissue PEDF gene expression is associated with insulin resistance
- (2013) J M Moreno-Navarrete et al. INTERNATIONAL JOURNAL OF OBESITY
- Pigment Epithelium-derived Factor (PEDF) Prevents Retinal Cell Death via PEDF Receptor (PEDF-R)
- (2013) Preeti Subramanian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Mouse Model for Human Osteogenesis Imperfecta Type VI
- (2013) Rosalind Bogan et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Significance of Plasma Levels of Pigment Epithelium-Derived Factor as Determined by Multidetector Row Computed Tomography in Patients with Mild Chronic Kidney Disease and/or Coronary Artery Disease
- (2013) Y Shiga et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Unknown
- (2013) Yanling Liu et al. MOLECULAR MEDICINE
- WNT signaling in bone homeostasis and disease: from human mutations to treatments
- (2013) Roland Baron et al. NATURE MEDICINE
- PEDF Expression Is Inhibited by Insulin Treatment in Adipose Tissue via Suppressing 11β-HSD1
- (2013) Yinli Zhou et al. PLoS One
- Pigment Epithelium-Derived Factor Enhances Differentiation and Mineral Deposition of Human Mesenchymal Stem Cells
- (2013) Feng Li et al. STEM CELLS
- Insulin resistance is associated with elevated serum pigment epithelium–derived factor (PEDF) levels in morbidly obese patients
- (2012) Arijeet K. Gattu et al. ACTA DIABETOLOGICA
- Association between plasma levels of pigment epithelium-derived factor and renal dysfunction in patients with coronary artery disease
- (2012) Tadaaki Arimura et al. Cardiology Journal
- The Future of Peptide-based Drugs
- (2012) David J. Craik et al. Chemical Biology & Drug Design
- Angiogenesis in Pulmonary Fibrosis
- (2012) Chandru Hanumegowda et al. CHEST
- Therapeutic Potential of a Monoclonal Antibody Blocking the Wnt Pathway in Diabetic Retinopathy
- (2012) K. Lee et al. DIABETES
- Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice
- (2012) Paul J Grippo et al. GUT
- Matrix metalloprotein-9 activation under cell-to-cell interaction between endothelial cells and monocytes: possible role of hypoxia and tumor necrosis factor-α
- (2012) Yuko Yamamoto et al. HEART AND VESSELS
- Lack of Circulating Pigment Epithelium-Derived Factor Is a Marker of Osteogenesis Imperfecta Type VI
- (2012) Frank Rauch et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Imbalanced levels of angiogenic and angiostatic factors in vitreous, plasma and postmortem retinal tissue of patients with proliferative diabetic retinopathy
- (2012) Nithyakalyani Mohan et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- Estrogen-Induced Retinal Endothelial Cell Proliferation: Possible Involvement of Pigment Epithelium-Derived Factor and Phosphoinositide 3-Kinase/Mitogen-Activated Protein Kinase Pathways
- (2012) Kalpana Parvathaneni et al. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
- PEDF-derived peptide inhibits corneal angiogenesis by suppressing VEGF expression
- (2012) Takanori Matsui et al. MICROVASCULAR RESEARCH
- Vitreous Levels of Proteins Implicated in Angiogenesis Are Modulated in Patients with Retinal or Choroidal Neovascularization
- (2012) Matthias Huber et al. OPHTHALMOLOGICA
- Hypoxia Negatively Regulates Antimetastatic PEDF in Melanoma Cells by a Hypoxia Inducible Factor-Independent, Autophagy Dependent Mechanism
- (2012) Asunción Fernández-Barral et al. PLoS One
- Long-Term Retinal PEDF Overexpression Prevents Neovascularization in a Murine Adult Model of Retinopathy
- (2012) Virginia Haurigot et al. PLoS One
- Characterisation of the vitreous proteome in proliferative diabetic retinopathy
- (2012) Hao Wang et al. Proteome Science
- Pigment Epithelium-Derived Factor Associates With Neuropathy and Fibrosis in Pancreatic Cancer
- (2011) Tamar Samkharadze et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Exome Sequencing Identifies Truncating Mutations in Human SERPINF1 in Autosomal-Recessive Osteogenesis Imperfecta
- (2011) Jutta Becker et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Correlation between Ficolin-3 and Vascular Endothelial Growth Factor-to-Pigment Epithelium-Derived Factor Ratio in the Vitreous of Eyes with Proliferative Diabetic Retinopathy
- (2011) Bingqing Zheng et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Overexpression of Pigment Epithelium–Derived Factor Inhibits Retinal Inflammation and Neovascularization
- (2011) Kyoungmin Park et al. AMERICAN JOURNAL OF PATHOLOGY
- Pigment Epithelium-Derived Factor Regulates Early Pancreatic Fibrotic Responses and Suppresses the Profibrotic Cytokine Thrombospondin-1
- (2011) John C. Schmitz et al. AMERICAN JOURNAL OF PATHOLOGY
- Blood vessel formation in the tissue-engineered bone with the constitutively active form of HIF-1α mediated BMSCs
- (2011) Duohong Zou et al. BIOMATERIALS
- PEDF inhibits IL8 production in prostate cancer cells through PEDF receptor/phospholipase A2 and regulation of NFκB and PPARγ
- (2011) Jennifer Hirsch et al. CYTOKINE
- Defective Glycogenesis Contributes Toward the Inability to Suppress Hepatic Glucose Production in Response to Hyperglycemia and Hyperinsulinemia in Zucker Diabetic Fatty Rats
- (2011) T. P. Torres et al. DIABETES
- Pigment Epithelium-Derived Factor Regulates Lipid Metabolism via Adipose Triglyceride Lipase
- (2011) M. L. Borg et al. DIABETES
- Microphthalmia-associated transcription factor acts through PEDF to regulate RPE cell migration
- (2011) Xiaoyin Ma et al. EXPERIMENTAL CELL RESEARCH
- A PEDF-Derived Peptide Inhibits Retinal Neovascularization and Blocks Mobilization of Bone Marrow-Derived Endothelial Progenitor Cells
- (2011) Richard Longeras et al. Experimental Diabetes Research
- Pigment epithelium-derived factor as an anticancer drug and new treatment methods following the discovery of its receptors: a patent perspective
- (2011) Katrina B Manalo et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Lack of expression ofSERPINF1, the gene coding for pigment epithelium-derived factor, causes progressively deforming osteogenesis imperfecta with normal type I collagen
- (2011) Giacomo Venturi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Identification of a Novel Inhibitor of the Canonical Wnt Pathway
- (2011) K. Park et al. MOLECULAR AND CELLULAR BIOLOGY
- Pigment Epithelium-Derived Factor Is an Intrinsic Antifibrosis Factor Targeting Hepatic Stellate Cells
- (2010) Tsung-Chuan Ho et al. AMERICAN JOURNAL OF PATHOLOGY
- NF- B balances vascular regression and angiogenesis via chromatin remodeling and NFAT displacement
- (2010) A. B. Aurora et al. BLOOD
- Growth suppression of cervical carcinoma by pigment epithelium-derived factor via anti-angiogenesis
- (2010) Jun Yang et al. CANCER BIOLOGY & THERAPY
- Phosphomimetic Mutants of Pigment Epithelium-Derived Factor with Enhanced Antiangiogenic Activity as Potent Anticancer Agents
- (2010) A. Konson et al. CANCER RESEARCH
- Exercise Training Stimulates Ischemia-Induced Neovascularization via Phosphatidylinositol 3-Kinase/Akt-Dependent Hypoxia-Induced Factor-1α Reactivation in Mice of Advanced Age
- (2010) Xian Wu Cheng et al. CIRCULATION
- The Role of Wnt Signaling in Physiological and Pathological Angiogenesis
- (2010) Elisabetta Dejana CIRCULATION RESEARCH
- The Role of PEDF in Tumor Growth and Metastasis
- (2010) D. Hoshina et al. CURRENT MOLECULAR MEDICINE
- Inhibition of Connective Tissue Growth Factor Overexpression in Diabetic Retinopathy by SERPINA3K via Blocking the WNT/ -Catenin Pathway
- (2010) B. Zhang et al. DIABETES
- Pigment epithelium-derived factor binds to cell-surface F1-ATP synthase
- (2010) Luigi Notari et al. FEBS Journal
- Pigment Epithelium-derived Factor and Its Phosphomimetic Mutant Induce JNK-dependent Apoptosis and p38-mediated Migration Arrest
- (2010) Alexander Konson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Placenta Growth Factor (PlGF), a Novel Inducer of Plasminogen Activator Inhibitor-1 (PAI-1) in Sickle Cell Disease (SCD)
- (2010) Nitin Patel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Natural Angiogenesis Inhibitor Signals through Erk5 Activation of Peroxisome Proliferator-activated Receptor γ (PPARγ)
- (2010) Dauren Biyashev et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Matrix Metalloproteinase-9 Mediates Hypoxia-Induced Vascular Leakage in the Brain via Tight Junction Rearrangement
- (2010) Alexander T Bauer et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Small hairpin loop RNA targeting HIF-1α down-regulates VEGF and up-regulates PEDF in human retinal pigment epithelial cells under hypoxic condition
- (2010) Qing Xiao et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Adenoviral Gene Delivery of Pigment Epithelium-Derived Factor Protects Striatal Neurons from Quinolinic Acid-Induced Excitotoxicity
- (2010) Tomomi Sanagi et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- HIF-1alpha and HIF-2alpha Are Differentially Activated in Distinct Cell Populations in Retinal Ischaemia
- (2010) Freya M. Mowat et al. PLoS One
- Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency
- (2010) Rodolfo Gonzalez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression and Purification of Functional Epitope of Pigment Epithelium-Derived Factor in E. coli with Inhibiting Effect on Endothelial Cells
- (2010) Qing Gong et al. PROTEIN JOURNAL
- Modulation of Thrombospondin 1 and Pigment Epithelium–Derived Factor Levels in Vitreous Fluid of Patients With Diabetes
- (2009) Shoujian Wang ARCHIVES OF OPHTHALMOLOGY
- PEDF regulates osteoclasts via osteoprotegerin and RANKL
- (2009) Toru Akiyama et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2
- (2009) Z Zhang et al. CELL DEATH AND DIFFERENTIATION
- Pigment Epithelium-Derived Factor Contributes to Insulin Resistance in Obesity
- (2009) Seamus Crowe et al. Cell Metabolism
- Short Pigment Epithelial-Derived Factor-Derived Peptide Inhibits Angiogenesis and Tumor Growth
- (2009) Y. Mirochnik et al. CLINICAL CANCER RESEARCH
- Dexamethasone Increases Pigment Epithelium-Derived Factor in Perfused Human Eyes
- (2009) Elizabeth M. Perruccio et al. CURRENT EYE RESEARCH
- Protective role of pigment epithelium-derived factor (PEDF) in early phase of experimental diabetic retinopathy
- (2009) Yumiko Yoshida et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Inhibition of corneal neovascularization with plasmid pigment epithelium-derived factor (p-PEDF) delivered by synthetic amphiphile INTeraction-18 (SAINT-18) vector in an experimental model of rat corneal angiogenesis
- (2009) Chien-Neng Kuo et al. EXPERIMENTAL EYE RESEARCH
- Pigment epithelium-derived factor (PEDF) as a therapeutic target in cardiovascular disease
- (2009) Kathrin Rychli et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Laminin Receptor Involvement in the Anti-angiogenic Activity of Pigment Epithelium-derived Factor
- (2009) Adrien Bernard et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nuclear Receptor Co-repressor Is Required to Maintain Proliferation of Normal Intestinal Epithelial Cells in Culture and Down-modulates the Expression of Pigment Epithelium-derived Factor
- (2009) Geneviève Doyon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cytosolic phospholipase A2-α is an early apoptotic activator in PEDF-induced endothelial cell apoptosis
- (2008) Tsung-Chuan Ho et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Rational design of minimal hypoxia-inducible enhancers
- (2008) Stefan Kaluz et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Administration of pigment epithelium-derived factor prolongs bleeding time by suppressing plasminogen activator inhibitor-1 activity and platelet aggregation in rats
- (2008) S. Yamagishi et al. CLINICAL AND EXPERIMENTAL MEDICINE
- Increased serum pigment epithelium-derived factor levels in type 1 diabetic patients with diabetic retinopathy
- (2008) Naoto Katakami et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Increased serum pigment epithelium derived factor levels in Type 2 diabetes patients
- (2008) Alicia Jenkins et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Serum levels of pigment epithelium-derived factor (PEDF) are positively associated with visceral adiposity in Japanese patients with type 2 diabetes
- (2008) Kazuo Nakamura et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- PEDF-deficient mice exhibit an enhanced rate of retinal vascular expansion and are more sensitive to hyperoxia-mediated vessel obliteration
- (2008) Qiong Huang et al. EXPERIMENTAL EYE RESEARCH
- Ethanol Exposure Depletes Hepatic Pigment Epithelium-Derived Factor, a Novel Lipid Regulator
- (2008) Chuhan Chung et al. GASTROENTEROLOGY
- Pigment Epithelium-derived Factor Binds to Hyaluronan
- (2008) S. Patricia Becerra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expression and purification of functional recombinant human pigment epithelium-derived factor (PEDF) secreted by the yeast Pichia pastoris
- (2008) Francisco Sánchez-Sánchez et al. JOURNAL OF BIOTECHNOLOGY
- Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL)
- (2008) Chuhan Chung et al. JOURNAL OF HEPATOLOGY
- Pigment epithelium-derived factor mitigates inflammation and oxidative stress in retinal pericytes exposed to oxidized low-density lipoprotein
- (2008) Sarah X Zhang et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Pigment Epithelium-Derived Factor and Interleukin-6 Control Prostate Neuroendocrine Differentiation via Feed-Forward Mechanism
- (2008) Norm D. Smith et al. JOURNAL OF UROLOGY
- Role of Soluble Vascular Endothelial Growth Factor Receptor-1 in the Vitreous in Proliferative Diabetic Retinopathy
- (2008) Nozomu Matsunaga et al. OPHTHALMOLOGY
- PROINFLAMMATORY CYTOKINES AND ANGIOGENIC AND ANTI-ANGIOGENIC FACTORS IN VITREOUS OF PATIENTS WITH PROLIFERATIVE DIABETIC RETINOPATHY AND EALES’ DISEASE
- (2008) PONNALAGU MURUGESWARI et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started